中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [299]
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OAI收割 [299]
内容类型
期刊论文 [297]
会议论文 [2]
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2023 [23]
2022 [31]
2021 [27]
2020 [23]
2019 [24]
2018 [25]
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Chemistry [9]
Pharmacolo... [2]
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浏览/检索结果:
共299条,第1-10条
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专题:上海药物研究所
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Interaction between membrane curvature sensitive factors SpoVM and SpoIVA in Bicelle condition
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 694, 页码: 5
作者:
Chen, Jiali
;
Wang, Yifan
;
Lin, Shuru
;
Yu, Quanxiang
;
Qi, Zhengfei
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/02/27
SpoVM
SpoIVA
Purification
Bicelles
Interaction
SpoVMP9A
A novel capsid-XL32-derived adeno-associated virus serotype prompts retinal tropism and ameliorates choroidal neovascularization
期刊论文
OAI收割
BIOMATERIALS, 2024, 卷号: 304, 页码: 13
作者:
Luo, Lin-Lin
;
Xu, Jie
;
Wang, Bing-Qiao
;
Chen, Chen
;
Chen, Xi
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
AAV
Capsid engineering
Phosphosites mutation
Retinal tropism
Neovascularization
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:
Cheng, Jing
;
Yan, Ziqin
;
Jiang, Kailong
;
Liu, Chen
;
Xu, Dehua
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/19
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Dihydro-β-agarofuran-type sesquiterpenoids from the seeds of
Tripterygium
wilfordii
(Thunder God Vine) and evaluation of their anti-osteoclastogenesis and immunosuppressive activities
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 19
作者:
Cao, Guangchao
;
Ning, Ruonan
;
Zhao, Jie
;
Yao, Jiaying
;
Chang, Linyue
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
Tripterygium wilfordii
Dihydro
beta -agarofuran sesquiterpenoid
Osteoclastgenesis
Immunosuppressive
Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids
期刊论文
OAI收割
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2023, 卷号: 185, 页码: 13-25
作者:
Zhao, Chengcheng
;
Jiang, Xiangrui
;
Peng, Liyuan
;
Zhang, Yan
;
Li, Huihui
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/01/16
Heart failure
Hypertrophy
Epoxyeicosatrienoic acids
Soluble epoxide hydrolase
Identification of a carbohydrate recognition motif of purinergic receptors
期刊论文
OAI收割
ELIFE, 2023, 卷号: 12, 页码: 17
作者:
Zhao, Lifen
;
Wei, Fangyu
;
He, Xinheng
;
Dai, Antao
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/19
G-protein coupled receptor
sugar nucleotide
recogonition mechanism
functional motif
Human
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Jiang, Xiangrui
;
Su, Haixia
;
Shang, Weijuan
;
Zhou, Feng
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Characterization of ginsenosides from
Panax japonicus
var.
major
(Zhu-Zi-Shen) based on ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry and desorption electrospray ionization-mass spectrometry imaging
期刊论文
OAI收割
CHINESE MEDICINE, 2023, 卷号: 18, 期号: 1, 页码: 14
作者:
Jiang, Meiting
;
Li, Xiaohang
;
Zhao, Yuying
;
Zou, Yadan
;
Bai, Maoli
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
Panax japonicus var. major
Ginsenoside
UHPLC/QTOF-MS
DESI-MSI
Precursor ions list
Spatial distribution
STING agonist-boosted mRNA immunization via intelligent design of nanovaccines for enhancing cancer immunotherapy
期刊论文
OAI收割
NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 10, 页码: 16
作者:
Zhou, Lei
;
Yi, Wenzhe
;
Zhang, Zehong
;
Shan, Xiaoting
;
Zhao, Zitong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
vaccine
mRNA
STING
cancer immunotherapy
nanoparticles