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Optimization of Brigatinib as New Wild-Type Sparing Inhibitors of EGFR(T790M/C797S) Mutants 期刊论文  OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 7
作者:  Li, Shan;  Zhang, Tao;  Zhu, Su-Jie;  Lei, Chong;  Lai, Mengzhen
  |  收藏  |  浏览/下载：25/0  |  提交时间：2022/06/15
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:  Xie, Hong-Xu;  Zhang, Juan;  Li, Yue;  Zhang, Jin-He
  |  收藏  |  浏览/下载：67/0  |  提交时间：2021/11/04
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:  Yu, Ming-cheng;  Yang, Feng;  Ding, Xiao-yu;  Sun, Nan-nan;  Jiang, Zheng-yuan
  |  收藏  |  浏览/下载：92/0  |  提交时间：2020/12/24
Asperbutenolide A, an unusual aromatic butenolide dimer with diverse bioactivities from a marine-derived fungus Aspergillus terreus SCAU011 期刊论文  OAI收割
TETRAHEDRON LETTERS, 2020, 卷号: 61, 期号: 32, 页码: 6
作者:  Bao, Jie;  Li, Xiu-Xiu;  He, Fei;  Zhang, Xiaoyong;  Zhu, Kongkai
  |  收藏  |  浏览/下载：19/0  |  提交时间：2020/12/24
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant 期刊论文  OAI收割
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287
作者:  Hu, Xianglong;  Xun, Qiuju;  Zhang, Tao;  Zhu, Su-Jie;  Li, Qian
  |  收藏  |  浏览/下载：79/0  |  提交时间：2020/07/01
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma 期刊论文  OAI收割
JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908
作者:  Dong, Liang-qing;  Peng, Li-hua;  Ma, Li-jie;  Liu, Dong-bing;  Zhang, Shu
  |  收藏  |  浏览/下载：79/0  |  提交时间：2020/07/01
High-throughput screening campaign identifies a small molecule agonist of the relaxin family peptide receptor 4 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Lin, Guang-yao;  Lin, Lin;  Cai, Xiao-qing;  Dai, An-tao;  Zhu, Yue
  |  收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01
Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFR(L858R/T790M/C797S)) 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7302-7308
作者:  Shen, Jiayi;  Zhang, Tao;  Zhu, Su-Jie;  Sun, Min;  Tong, Linjiang
  |  收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01
Discovery of JND3229 as a New EGFR(C797S) Mutant Inhibitor with In Vivo Monodrug Efficacy 期刊论文  OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 11, 页码: 1123-1127
作者:  Lu, Xiaoyun;  Zhang, Tao;  Zhu, Su-Jie;  Xun, Qiuju;  Tong, Lingjiang
  |  收藏  |  浏览/下载：107/0  |  提交时间：2019/01/08
Benzbromarone aggravates hepatic steatosis in obese individuals 期刊论文  OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2018, 卷号: 1864, 期号: 6, 页码: 2067-2077
作者:  Sun, Peng;  Zhu, Jing-Jie;  Wang, Ting;  Huang, Qi;  Zhou, Yu-Ren
  |  收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08