机构

• 上海药物研究所 [20]
• 理论物理研究所 [11]
• 大连化学物理研究所 [6]
• 国家空间科学中心 [4]
• 金属研究所 [2]
• 青岛生物能源与过程研... [2]
• 更多

采集方式

• OAI收割 [48]
• iSwitch采集 [2]

内容类型

• 期刊论文 [49]
• 会议论文 [1]

发表日期

• 2024 [1]
• 2023 [1]
• 2022 [1]
• 2021 [1]
• 2020 [2]
• 2019 [6]
• 更多

学科主题

• Physics [11]
• Astronomy ... [1]
• Materials ... [1]
• Multidisci... [1]
• Optics [1]

筛选

浏览/检索结果: 共50条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Characteristics and causes of a catastrophic snow avalanche that occurred on January 17, 2023, in Tibet 期刊论文  OAI收割 LANDSLIDES, 2024, 页码: 7 作者:  Chen, Ningsheng;  Li, Anhui;  Tian, Shufeng;  Rahman, Mahfuzur;  Huang, Na   |  收藏  |  浏览/下载：121/0  |  提交时间：2024/03/25 无   Discovery of toxoflavin,a potent IRE1α inhibitor acting through structure-dependent oxidative inhibition 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 234 作者:  Liu Changmei;  Nie Litong;  Jiang Haini;  Xu Lei;  Zhang Kunzhi   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/05/22 endoplasmic reticulum stress  toxoflavin  reactive oxygen species  IRE1α  XBP1   Sugemalimab versus placebo after concurrent or sequential chemoradiotherapy in patients with locally advanced, unresectable, stage III non-small-cell lung cancer in China (GEMSTONE-301): interim results of a randomised, double-blind, multicentre, phase 3 trial 期刊论文  OAI收割 LANCET ONCOLOGY, 2022, 卷号: 23 作者:  Zhou, Qing;  Chen, Ming;  Jiang, Ou;  Pan, Yi;  Hu, Desheng   |  收藏  |  浏览/下载：52/0  |  提交时间：2022/03/21 Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文  OAI收割 PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664 作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin   |  收藏  |  浏览/下载：47/0  |  提交时间：2021/12/01 IDH1-R132H inhibitors  synthesis  biological activity  docking  3-(indol-3-yl)-4-(pyrazolo-[3  4-c]pyridazin-3-yl)-maleimides   Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19 作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue   |  收藏  |  浏览/下载：41/0  |  提交时间：2020/12/21 Metabolic pathways  Isocitrate dehydrogenase 2  Conformational restriction  Macrocyclic derivatives  Inhibitors   Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19 作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/12/21 Metabolic pathways  Isocitrate dehydrogenase 2  Conformational restriction  Macrocyclic derivatives  Inhibitors   Mitochondrial Uncoupling Coordinated With PDH Activation Safely Ameliorates Hyperglycemia via Promoting Glucose Oxidation 期刊论文  OAI收割 DIABETES, 2019, 卷号: 68, 期号: 12, 页码: 2197-2209 作者:  Jiang, Haowen;  Jin, Jia;  Duan, Yanan;  Xie, Zhifu;  Li, Yufeng   |  收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01 Selective Late-Stage Oxygenation of Sulfides with Ground-State Oxygen by Uranyl Photocatalysis 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 页码: 9 作者:  Li, Yiming   |  收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01 oxygen  oxygenation  photocatalysis  sulfides  uranyl catalysis   Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62 作者:  Tong, Lexian;  Song, Pinrao;  Jiang, Kailong;  Xu, Lei;  Jin, Tingting   |  收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01 CHK1 kinase inhibitor  Selectivity  Monotherapy  Hematologic malignancies   Discovery of novel indoleaminopyrimidine NIK inhibitors based on molecular docking-based support vector regression (SVR) model 期刊论文  OAI收割 CHEMICAL PHYSICS LETTERS, 2019, 卷号: 718, 页码: 38-45 作者:  Ye, Qing;  Li, Qiu;  Gao, Anhui;  Ying, Huazhou;  Cheng, Gang   |  收藏  |  浏览/下载：10/0  |  提交时间：2020/07/01