中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
水生生物研究所 [4]
武汉植物园 [3]
理论物理研究所 [1]
宁波材料技术与工程研... [1]
国家天文台 [1]
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OAI收割 [21]
内容类型
期刊论文 [21]
发表日期
2023 [5]
2021 [3]
2020 [1]
2019 [8]
2018 [4]
学科主题
Astronomy ... [1]
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Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13
作者:
Yang, Hanxi
;
You, Mengyuan
;
Shu, Xiaoyang
;
Zhen, Jingyao
;
Zhu, Mengwei
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Peptidomimetics
Benzothiazolyl ketone
3CLpro inhibitor
Pharmacokinetic properties
SARS-CoV-2
Development of HSP90 inhibitors-SN38 conjugates for cancer treatment
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 137, 页码: 11
作者:
Cao, Yuting
;
Shen, Qianqian
;
Ding, Mengyuan
;
Chen, Yi
;
Lu, Wei
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2023/10/17
HSP90
SN38 conjugate
Drug accumulation
Cancer treatment
Synthesis, and biological evaluation of EGFR/HER2-NAMPT conjugates for tumor treatment
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2023, 页码: 20
作者:
Ding, Mengyuan
;
Shen, Qianqian
;
Lu, Wei
;
Zhu, Shulei
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2023/10/17
EGFR
HER2
NAMPT
Resistance
Selectivity
Molecular docking
Design, synthesis and biological evaluation of covalent peptidomimetic 3CL protease inhibitors containing nitrile moiety
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12
作者:
Zhu, Mengwei
;
Fu, Tiantian
;
You, Mengyuan
;
Cao, Junyuan
;
Yang, Hanxi
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/17
COVID-19
SARS-CoV-2
3CL protease
Nirmatrelvir
Peptidomimetic inhibitors
Quench Protection Modeling of an HTS Magnet for MRI System
期刊论文
OAI收割
IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY, 2021, 卷号: 31
作者:
Shen, Boyang
;
Chen, Xiaoyuan
;
Liu, Huajun
;
Ni, Zhipeng
;
Shi, Yi
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2021/11/01
High-temperature superconductor (HTS)
HTS magnet
Quench
Finite element method (FEM)
H-formulation
Hot spot temperature
Magnetic Exchange Field Modulation of Quantum Hall Ferromagnetism in 2D van der Waals CrCl3/Graphene Heterostructures
期刊论文
OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2021, 卷号: 13, 期号: 8, 页码: 10656-10663
作者:
Wu, Yanfei
;
Cui, Qirui
;
Zhu, Mengyuan
;
Liu, Xinjie
;
Wang, Yi
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/12/01
Early pregnancy loss: Do Per- and polyfluoroalkyl substances matter?
期刊论文
OAI收割
ENVIRONMENT INTERNATIONAL, 2021, 卷号: 287, 页码: -
作者:
Wang, Bin
;
Fu, Jianjie
;
Gao, Ke
;
Liu, Qian
;
Zhuang, Lili
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2022/01/04
Low temperature indirect thermal desorption
Green and sustainable remediation
Lube oil
Removal behaviors
Physicochemical properties
Microbial community recolonization
Palladium-mediated Suzuki-Miyaura Cross-Coupling Reaction of Potassium Boc-protected aminomethyltrifluoroborate with DNA-Conjugated aryl bromides for DNA-Encoded chemical library synthesis
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 卷号: 533, 期号: 2, 页码: 209-214
作者:
Qu, Yi
;
Liu, Sixiu
;
Wen, Huanan
;
Xu, Yanfen
;
An, Yulong
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/12/24
DNA Encoded chemistry
Suzuki-miyaura cross-coupling
Potassium trifluoroborates
Trophic Status Is Associated With Community Structure and Metabolic Potential of Planktonic Microbiota in Plateau Lakes
期刊论文
OAI收割
FRONTIERS IN MICROBIOLOGY, 2019, 卷号: 10, 期号: 1, 页码: 15
作者:
Shen, Mengyuan
;
Li, Qi
;
Ren, Minglei
;
Lin, Yan
;
Wang, Juanping
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/04/07
metagenomics
trophic status
taxonomic diversity
community structure
metabolic potential
planktonic microbiota
lake ecosystem
Cyanobacterial bloom