中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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西安光学精密机械研... [12]
半导体研究所 [9]
上海药物研究所 [8]
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期刊论文 [62]
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Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:
Qin, Ying
;
Li, Dekang
;
Qi, Chunting
;
Xiang, Huaijiang
;
Meng, Huyan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/03/06
RIPK1
Necroptosis
Type-II kinase inhibitors
Rational design
Lead optimization
Structure-activity relationship
Anti-inflammation
Preclinical drug discovery
Saikosaponin D improves nonalcoholic fatty liver disease via gut microbiota-bile acid metabolism pathway
期刊论文
OAI收割
Food Science and Human Wellness, 2023
作者:
Li, Lan
;
Yang, Shengye
;
Liang, Xinyu
;
Liu, Yameng
;
Xu, Hualing
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/26
Gut Microbiota
Non-alcoholic Fatty Liver Disease
Ssd
Bile Acids
Farnesoid x Receptor
Ootheca mantidis mitigates renal fibrosis in mice by the suppression of apoptosis via increasing the gut microbe
Akkermansia
muciniphila
and modulating glutamine metabolism
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2023, 卷号: 166, 页码: 15
作者:
Wang, Jue
;
Guo, Xiaozhen
;
Zou, Ziyuan
;
Yu, Minjun
;
Li, Xueling
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/08
Ootheca mantidis
Unilateral ureteral obstruction
Renal interstitial fibrosis
Apoptosis
Akkermansia muciniphila
Glutamine
HIF-1 alpha inhibition in macrophages preserves acute liver failure by reducing IL-1 beta production
期刊论文
OAI收割
FASEB JOURNAL, 2023, 卷号: 37, 期号: 9, 页码: 12
作者:
Kong, Xiangrong
;
Liu, Wei
;
Zhang, Xinwen
;
Zhou, Chendong
;
Sun, Xinyu
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
acute liver failure
cell death
HIF-1 alpha inhibitor
interleukin-1 beta
macrophage
FeCrypto: Instruction Set Architecture for Cryptographic Algorithms Based on FeFET-Based In-Memory Computing
期刊论文
OAI收割
IEEE TRANSACTIONS ON COMPUTER-AIDED DESIGN OF INTEGRATED CIRCUITS AND SYSTEMS, 2023, 卷号: 42, 期号: 9, 页码: 2889-2902
作者:
Liu, Rui
;
Zhang, Xiaoyu
;
Xie, Zhiwen
;
Wang, Xinyu
;
Li, Zerun
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/04
Computing-in-memory (CiM)
cryptographic algorithm
ferroelectric field-effect transistor (FeFET)
instruc-tion set architecture (ISA)
Avoided mode-crossing assisted single soliton formation
期刊论文
OAI收割
OPTICS AND LASER TECHNOLOGY, 2023, 卷号: 161
作者:
Wang, Xinyu
;
Wang, Wei-qiang
;
Xie, Peng
;
Wang, Yang
;
Chu, Sai T.
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/21
Microresonator
AMX
Native mode spaced microcomb
Single soliton
Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 2, 页码: 739-753
作者:
Xie, Zhifu
;
Zhang, Mei
;
Song, Qian
;
Cheng, Long
;
Zhang, Xinwen
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Hypercholesterolemia
Atherosclerosis
Liver
ATP-Citrate lyase (ACLY)
Lipogenesis
Cholesterol efflux
ACLY inhibitor
Chapter Nine - Targeting the super elongation complex for oncogenic transcription driven tumor malignancies: Progress in structure, mechanisms and small molecular inhibitor discovery
专著章节
OAI收割
出自: Advances in Cancer Research, England:Elsevier, 2023, 页码: 387-421
作者:
Wu, Xinyu
;
Xie, Yanqiu
;
Zhao, Kehao
;
Lu, Jing
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/26
Theoretical analysis and experimental verification of large deformation electro-osmosis consolidation treatment of dredged slurry
期刊论文
OAI收割
ENGINEERING GEOLOGY, 2023, 卷号: 312
作者:
Ge, Shangqi
;
Jiang, Wenhao
;
Zheng, Lingwei
;
Xie, Xinyu
;
Xie, Kanghe
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2023/08/02
Dredged slurry
Large deformation
Electro-osmosis consolidation
Finite difference method
Electro-osmosis experiments
Limosilactobacillus reuteri and caffeoylquinic acid synergistically promote adipose browning and ameliorate obesity-associated disorders
期刊论文
OAI收割
MICROBIOME, 2022, 卷号: 10, 期号: 1, 页码: 22
作者:
Liu, Yameng
;
Zhong, Xianchun
;
Lin, Suqin
;
Xu, Hualing
;
Liang, Xinyu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
Obesity
Prebiotic
Probiotics
Short-chain fatty acids
Propionate
Thermogenesis
Browning