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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [19]
采集方式
OAI收割 [19]
内容类型
期刊论文 [19]
发表日期
2021 [19]
学科主题
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浏览/检索结果:
共19条,第1-10条
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存缴方式:oaiharvest
发表日期:2021
专题:上海药物研究所
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Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2021, 页码: 24
作者:
Shao, Zhehua
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/06/15
Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Li, Teng-teng
;
Peng, Cheng
;
Wang, Ji-qiu
;
Xu, Zhi-jian
;
Su, Ming-bo
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2022/01/18
DPP4
distal mutation
enzymatic activity
molecular dynamics simulation
structure-function mechanism
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:
Wang, Shuni
;
Yang, Hong
;
Su, Mingbo
;
Lian, Fulin
;
Cong, Zhanqing
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2021/11/04
NSD2
Methyltransferase
HTS
Multiple myeloma
5-Aminonaphthalene derivatives
Inhibitor
New formamidobisabolene-type sesquiterpenoids from a Hainan Sponge Halichondria sp.
期刊论文
OAI收割
TETRAHEDRON, 2021, 卷号: 96, 页码: 7
作者:
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收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/11/04
Sponge
Halichondria sp
Anti-inflammatory activity
Sesquiterpenes
Unusual polyoxygenated casbane diterpenoids from the South China Sea soft coral Sinularia erecta
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 8
作者:
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收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/11/04
Soft coral
Sinularia erecta
Casbane
Stereochemistry
Anti-inflammatory activity
Engineering Chameleon Prodrug Nanovesicles to Increase Antigen Presentation and Inhibit PD-L1 Expression for Circumventing Immune Resistance of Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2021, 页码: 12
作者:
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收藏
  |  
浏览/下载:59/0
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提交时间:2021/11/04
antigen presentation
autophagy inhibition
immune resistance
immunotherapy
prodrug nanovesicles
Catalytic System-Controlled Divergent Reaction Strategies for the Construction of Diversified Spiropyrazolone Skeletons from Pyrazolidinones and Diazopyrazolones
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 8
作者:
Fang, Feifei
;
Hu, Shulei
;
Li, Chunpu
;
Wang, Qian
;
Wang, Run
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/11/04
[n+1] annulation
C(sp(3))-H bond activation
N-N bond activation
pyrazolidinones
spiropyrazolones
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:
Xu, Dandan
;
Sun, Deqiao
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/08/17
Axl
Cancer
Inhibitor
Pyrrolo[2,3-d]pyrimidine
Discovery of a potent, selective, and covalent ZAP-70 kinase inhibitor
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 219, 页码: 12
作者:
Rao, Danni
;
Li, Heng
;
Ren, Xuelian
;
Sun, Yaoliang
;
Wen, Cuiyun
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/08/17
Zeta-chain associated protein kinase 70 kDa (ZAP-70)
Covalent inhibitor
T cell
Autoimmune diseases
Diversity-oriented synthesis of cembranoid derivatives as potential anti-inflammatory agents
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 111, 页码: 8
作者:
Zhang, Cong
;
Li, Heng
;
Liu, Jin
;
Liu, Moting
;
Zhang, Hao
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/08/17
Marine natural product
Cembranoid
Anti-inflammation
molecular docking
structuremodification
Structure Activity Relationship