中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [19]
采集方式
OAI收割 [19]
内容类型
期刊论文 [19]
发表日期
2021 [19]
学科主题
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浏览/检索结果:
共19条,第1-10条
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发表日期:2021
专题:上海药物研究所
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Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 52, 页码: 12
作者:
Ding, Hong
;
Pei, Yuan
;
Li, Yuanqing
;
Xu, Wen
;
Mei, Lianghe
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
Epigenetics
Histone acetyltransferase
P300/CBP
Ovarian cancer
Concise synthesis of N-phosphorylated amides through three-component reactions
期刊论文
OAI收割
GREEN CHEMISTRY, 2021, 页码: 5
作者:
Zhu, Yuan-Yuan
;
Zhang, Tao
;
Zhou, Linlin
;
Yang, Shang-Dong
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/12/16
Exploring biological basis of Syndrome differentiation in coronary heart disease patients with two distinct Syndromes by integrated multi-omics and network pharmacology strategy
期刊论文
OAI收割
Chinese Medicine, 2021, 卷号: 16, 期号: 1
作者:
Wu,Gaosong
;
Zhao,Jing
;
Zhao,Jing
;
Song,Nixue
;
Zheng,Ningning
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2021/12/01
Coronary heart disease
Syndrome differentiation
Traditional Chinese Medicine
Proteomics
Metabolomics
Network pharmacology
Kynurenine derivative 3-HAA is an agonist ligand for transcription factor YY1
期刊论文
OAI收割
Journal of Hematology & Oncology, 2021, 卷号: 14, 期号: 1
作者:
Shi,Zhaopeng
;
Gan,Guifang
;
Xu,Xiang
;
Zhang,Jieying
;
Yuan,Yuan
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/11/04
3-Hydroxyanthronic acid (3-HAA)
Kynurenine
YY1
DUSP6
Hepatocellular carcinoma (HCC)
Tryptophan metabolism
Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Huang, He-ming
;
Fan, Shi-jie
;
Zhou, Xiao-ru
;
Liu, Yan-jun
;
Li, Xiao
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/11/04
nonalcoholic steatohepatitis
inflammation
histone deacetylase inhibitor
givinostat
epigenetics
PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation
期刊论文
OAI收割
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 7, 页码: 10
作者:
Yang, Jun
;
Wang, Juan
;
Liu, Yuan
;
Zhang, Yu
;
Huang, Wenjing
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/08/17
Four new diterpenoids from the twigs and leaves of Phyllanthus acidus
期刊论文
OAI收割
TETRAHEDRON, 2021, 卷号: 91, 页码: 6
作者:
Yuan, Yu-Rong
;
Li, Yan-Wen
;
Huang, Yi-Qi
;
Liu, Qun-fang
;
Ren, Yu-Hao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/08/17
Phyllanthus acidus
Cleistanthane-type diterpenoid
ECD calculation
Biosynthetic pathway
Cytotoxicity
Stimuli-activatable nanomaterials for phototherapy of cancer
期刊论文
OAI收割
BIOMEDICAL MATERIALS, 2021, 卷号: 16, 期号: 4, 页码: 11
作者:
Zhou, Mengjiao
;
Liu, Xiao
;
Chen, Fangmin
;
Yang, Lili
;
Yuan, Minjian
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/06/11
cancer treatment
photodynamic therapy
photothermal therapy
intelligent nanomaterials
stimuli-responsiveness
Cinnacetals A and B: Two highly oxidated and modified isoryanodane diterpenoids from Cinnamomum cassia
期刊论文
OAI收割
TETRAHEDRON LETTERS, 2021, 卷号: 73, 页码: 5
作者:
Huang, Yi-Qi
;
Zhou, Bin
;
Yuan, Yu-Rong
;
Ren, Yu-Hao
;
Li, Dong-Li
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/08/17
Cinnamomum cassia
Isoryanodane diterpenoid
X-ray crystallography
ECD calculation
Biosynthetic pathway
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:
Yang, Xiangbo
;
Wang, Zhijia
;
Pei, Yuan
;
Song, Ning
;
Xu, Lei
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/08/17
SHP2 degradation
Proteolysis targeting chimera (PROTAC)
Thalidomide-based heterobifunctional molecules
E3 ubiquitin ligase
CRBN