机构

• 上海药物研究所 [221]

采集方式

• OAI收割 [221]

内容类型

• 期刊论文 [221]

发表日期

• 2024 [5]
• 2023 [23]
• 2022 [19]
• 2021 [27]
• 2020 [14]
• 2019 [15]
• 更多

学科主题

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浏览/检索结果: 共221条，第1-10条 帮助 限定条件 内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Discovery of a Covalent Inhibitor Selectively Targeting the Autophosphorylation Site of c-Src Kinase 期刊论文  OAI收割 ACS CHEMICAL BIOLOGY, 2024, 页码: 12 作者:  Zhang, Huimin;  Xu, Dounan;  Huang, Hongchan;  Jiang, Hao;  Hu, Linghao   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4739-4756 作者:  Zhong, Ye;  Xu, Jing;  Zhou, Ruochen;  Tang, Li;  Ding, Shaoyue   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/05/07 PROTAC Prodrug-Integrated Nanosensitizer for Potentiating Radiation Therapy of Cancer 期刊论文  OAI收割 ADVANCED MATERIALS, 2024, 页码: 12 作者:  Zhang, Shunan;  Lai, Yi;  Pan, Jiaxing;  Saeed, Madiha;  Li, Shiqin   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/04/09 active tumor targeting  nanosensitizer  PROTAC prodrug  radiation therapy  tumor microenvironment   Comprehensive analysis of phenylpropanoids and butylidenephthalides in Angelica sinensis (Oliv.) Diels from different regions and processing methods by high-performance liquid chromatography combined with chemometrics 期刊论文  OAI收割 EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 2024, 页码: 16 作者:  Sun, Yan;  Zhou, Jing;  Hu, Yuxin;  Chen, Sihan;  Ni, Hui   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/02/27 Angelicae Sinensis radix  Origin  Chemometrics  Fingerprints  Single standard to determine the multi-components   Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies 期刊论文  OAI收割 CELL, 2024, 卷号: 187, 期号: 1, 页码: 49 作者:  Liu, Qian;  Zhang, Jing;  Guo, Chenchen;  Wang, Mengcheng;  Wang, Chenfei   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/02/19 A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   The claustrum-prelimbic cortex circuit through dynorphin/κ-opioid receptor signaling underlies depression-like behaviors associated with social stress etiology 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 17 作者:  Wang, Yu-Jun;  Zan, Gui-Ying;  Xu, Cenglin;  Li, Xue-Ping;  Shu, Xuelian   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/02/19 A novel branched galacturonan from Gardenia jasminoides alleviates liver fibrosis linked to TLR4/NF-kappa B signaling 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 245, 页码: 14 作者:  Ma, Xiaonan;  Zhou, Wanqi;  Nie, Yingmin;  Jing, Xiaoqi;  Li, Saijuan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Polysaccharides  Pectin  Gardenia jasminoides  Liver fibrosis  TLR4  NF-kappa B