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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [425]
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期刊论文 [425]
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2024 [10]
2023 [34]
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2020 [30]
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Chemistry [5]
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共425条,第1-10条
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内容类型:期刊论文
专题:上海药物研究所
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Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:
Li, Yuan
;
Xu, Tingting
;
Zhao, Yue
;
Zhang, Hui
;
Liu, Zesheng
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/05/07
RIPK1 inhibitor ameliorates pulmonary injury by modulating the function of neutrophils and vascular endothelial cells
期刊论文
OAI收割
CELL DEATH DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 12
作者:
Yang, Tao
;
Xiang, Cai-gui
;
Wang, Xiao-han
;
Li, Qing-qing
;
Lei, Shu-yue
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Design and Synthesis of Cyclolipopeptide Mimics of Dysoxylactam A and Evaluation of the Reversing Potencies against P-Glycoprotein-Mediated Multidrug Resistance
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4560-4582
作者:
Yang, Guan-Zhou
;
Wang, Lei
;
Gao, Kun
;
Zhu, Xi
;
Lou, Li-Guang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 19
作者:
Chen, Yuting
;
Wang, Zekun
;
Zhang, Junjie
;
Shi, Qiongyu
;
Yang, Hong
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
PRMT5
Nucleoside derivatives
Methyltransferases
Structure -activity relationship
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
;
Xu, Haiyan
;
Xu, Yixiang
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/25
Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486
作者:
Chang, Qi
;
Li, Jiayi
;
Deng, Yue
;
Zhou, Ruilin
;
Wang, Bingwei
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/03/25
EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells (vol 41, pg 270, 2020)
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 2
作者:
Chen, Yue-hong
;
Lv, Hao
;
Shen, Ning
;
Wang, Xiao-min
;
Tang, Shuai
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/03/06
Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1079-1092
作者:
Qin, Shaozhao
;
Feng, Lijian
;
Zhao, Qingyi
;
Yan, Ziqin
;
Lyu, Xilin
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/27
Tumor-Associated Macrophage Targeting of Nanomedicines in Cancer Therapy
期刊论文
OAI收割
PHARMACEUTICS, 2024, 卷号: 16, 期号: 1, 页码: 28
作者:
Kang, Xuejia
;
Huang, Yongzhuo
;
Wang, Huiyuan
;
Jadhav, Sanika
;
Yue, Zongliang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/02/27
tumor-associated macrophage
suppressive immune environment
tumor proliferation and metastasis
nanomedicine
targeted delivery systems
Visualization of nasal powder distribution using biomimetic human nasal cavity model
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 392-404
作者:
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Nasal drug deposition
Nasal drug distribution
Nasal drug delivery
Biomimetic nasal model
Nasal powder
Three-dimensional reconstruction
Three-dimensional printing