中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Fatty acid esters of hydroxy fatty acids: A potential treatment for obesity-related diseases
期刊论文
OAI收割
OBESITY REVIEWS, 2024, 页码: 11
作者:
Li, Lili
;
Wang, Ping
;
Jiao, Xudong
;
Qin, Song
;
Liu, Zhengyi
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
adipose tissue
diabetes
fatty acid esters of hydroxy fatty acids
inflammation
structure-activity relationship
Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 inhibitors: Research progress and prospects
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 13
作者:
Guan, Dezhong
;
Fang, Lincheng
;
Feng, Mingshun
;
Guo, Shi
;
Xie, Lingfeng
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
ENPP1 inhibitors
cGAS-STING pathway
2 ', 3 '-cGAMP
Tumor immunotherapy
Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 91, 页码: 11
作者:
Zhao, Yitian
;
Zhang, Min
;
Hou, Xudong
;
Han, Jiaxin
;
Qin, Xiaoya
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
Salicylanilide
hPL inhibitor
Structure -activity relationship
Anti -obesity
Optimization of potent, selective and orally bioavailable biphenyl scaffold as FABP4 inhibitors for anti-inflammation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 16
作者:
He, Yulong
;
Li, Shunyi
;
Zhu, Yueyue
;
Wang, Yujie
;
Chen, Yuqi
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2023/10/17
Structure-activity relationship
FABP4 inhibitor
Biphenyl scaffold
Selectivity
Oral bioavailability
Anti-inflammation
Phenotypic screening-based drug discovery of furan-2-carboxylic acid derivatives for the amelioration of type 2 diabetes mellitus (T2DM)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 246, 页码: 11
作者:
Chen, Lili
;
Huang, Suling
;
Ye, Yangliang
;
Shen, Yu
;
Xu, Tifei
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
Phenotypic screening
Gluconeogenesis
Furan-2-carboxylic acid
T2DM
Efficient Detection of Pre-Proinsulin by Double Antibody Sandwich ELISA
期刊论文
OAI收割
APPLIED SCIENCES-BASEL, 2022, 卷号: 12
作者:
Zhu, Zhu
;
Wang, Han
;
Wang, Li
;
Wei, Zhou
;
Zheng, Zhiming
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/22
recombinant human insulin
pre-proinsulin
monoclonal antibody
sandwich ELISA
Development and structure–activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
Natural Products and Bioprospecting, 2022, 卷号: 12, 期号: 1
作者:
Deng,Xu
;
Huang,Su-Ling
;
Ren,Jian
;
Pan,Zheng-Hong
;
Shen,Yu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/11/11
Metabolic syndrome
Tanshinones
Selective 11β-HSD1 inhibitors
Structure–activity relationships
Development and structure-activity relationships of tanshinones as selective 11beta-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
Natural products and bioprospecting, 2022, 卷号: 12, 期号: 1, 页码: 36
作者:
Deng, Xu
;
Huang, Su-Ling
;
Ren, Jian
;
Pan, Zheng-Hong
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/15
Metabolic syndrome
Selective 11beta-HSD1 inhibitors
Structure-activity relationships
Tanshinones
Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 14
作者:
Huang, Su-Ling
;
Xie, Wei
;
Ye, Yang-Liang
;
Liu, Jia
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/11/11
type 2 diabetes mellitus
coronarin A
glycogen synthesis
gluconeogenesis
mTORC1
IRS1
Co-activating the AMPK signaling axis by low molecular weight fucoidan LF2 and fucoxanthin improves the HFD-induced metabolic syndrome in mice
期刊论文
OAI收割
JOURNAL OF FUNCTIONAL FOODS, 2022, 卷号: 94, 页码: 9
作者:
Deng, Zhenzhen
;
Wang, Jing
;
Wu, Ning
;
Geng, Lihua
;
Zhang, Quanbin
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/08/17
Fucoxanthin
Fucoidan
Metabolic Syndrome
AMPK Signaling Axis