中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14
作者:
Xie, Xiong
;
Lan, Qiaoshuai
;
Zhao, Jinyi
;
Zhang, Sulin
;
Liu, Lu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
CsIL-20, a tongue sole interleukin-20, negatively mediates leucocyte activity and antibacterial defense
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2024, 卷号: 145, 页码: 9
作者:
Zhao, Kun-yu
;
Huang, Hui
;
Jin, Qiu
;
Jiao, Xu-dong
;
Li, Xue-peng
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/05/07
Interleukin-20
Cynoglossus semilaevis
Expression patterns
PBLs activity
Antibacterial immunity
LncRNA pol-lnc78 as a ceRNA regulates antibacterial responses via suppression of pol-miR-n199-3p-mediated SARM down-regulation in Paralichthys olivaceus
期刊论文
OAI收割
ZOOLOGICAL RESEARCH, 2024, 卷号: 45, 期号: 1, 页码: 25-35
作者:
Ning, Xian-Hui
;
Han, Bing
;
Peng, Ye
;
Yin, Shao-Wu
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/07
LncRNA
SARM
miRNA
ceRNA
Antibacterial response
Low-Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 17
作者:
Pu, Congying
;
Li, Yize
;
Fu, Yixian
;
Yan, Yiyang
;
Tao, Siyao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/02/27
AIM2 inflammasome
chemotherapy
gut microbiome
ileal epithelial cells
immune checkpoint blockade
lactobacillus
segmented filamentous bacterium
The Toll pathway and Duox-ROS system are required for the clam antibacterial immune response in the hepatopancreas
期刊论文
OAI收割
AQUACULTURE, 2023, 卷号: 574, 页码: 10
作者:
Yu, Jiajia
;
Teng, Shuangshuang
;
Yue, Xin
;
Wang, Hongxia
;
Liu, Baozhong
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/13
Meretrix petechialis
Vibrio parahaemolyticus
Vibrio load
Toll pathway
ROS system
Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 15
作者:
Wang, Qian
;
Chen, Guofeng
;
He, Jian
;
Li, Jiameng
;
Xiong, Muya
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
SARS-CoV-2
papain-like protease
covalent inhibitor
co-crystal structure
in vitro assay
Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS-CoV-2 Papain-Like Protease
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 10
作者:
Hu, Hangchen
;
Wang, Qian
;
Su, Haixia
;
Shao, Qiang
;
Zhao, Wenfeng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
Allosteric Modulator
Cysteine 270
Drug Design
Papain-Like Protease
SARS-CoV-2
Simplified Cell Magnetic Isolation Assisted SC2 Chip to Realize "Sample in and Chemotaxis Out": Validated by Healthy and T2DM Patients' Neutrophils
期刊论文
OAI收割
MICROMACHINES, 2022, 卷号: 13
作者:
Yang, Xiao
;
Gao, Chaoru
;
Liu, Yong
;
Zhu, Ling
;
Yang, Ke
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/12/23
neutrophil
microfluidic chip
isolation
chemotaxis test
diabetes mellitus type 2 (T2DM)
Phycocyanin: Anti-inflammatory effect and mechanism
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2022, 卷号: 153, 页码: 10
作者:
Liu, Runze
;
Qin, Song
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/11/07
Phycocyanin
Phycocyanobilin
Inflammation
Signal pathway
Heme oxygenase 1
Kelch-like ECH-associated protein 1
Hemin protects against Zika virus infection by disrupting virus-endosome fusion
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2022, 卷号: 203, 页码: 11
作者:
Xu, Meng-Meng
;
Wu, Bing
;
Huang, Guan-Gen
;
Feng, Chun-Lan
;
Wang, Xiao-Han
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/08/16
Zika virus
Hemin
Antiviral
Inflammation
HO-1
Viral fusion