中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
机构
采集方式
内容类型
发表日期
学科主题
筛选

浏览/检索结果: 共211条，第1-10条 帮助

条数/页： 排序方式：
DockingGA: enhancing targeted molecule generation using transformer neural network and genetic algorithm with docking simulation 期刊论文  OAI收割
BRIEFINGS IN FUNCTIONAL GENOMICS, 2024, 页码: 12
作者:  Gao, Changnan;  Bao, Wenjie;  Wang, Shuang;  Zheng, Jianyang;  Wang, Lulu
  |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/20
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:  Sun, Yaoliang;  Chen, Zhiwen;  Liu, Guobin;  Chen, Xiaoai;  Shi, Zihan
  |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/25
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:  Zhang, Hongjin;  Lin, Guohao;  Jia, Suyun;  Zhang, Ying;  Wu, Jianbo
  |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan
  |  收藏  |  浏览/下载：18/0  |  提交时间：2024/03/25
Sequence-based drug design as a concept in computational drug design 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21
作者:  Chen, Lifan;  Fan, Zisheng;  Chang, Jie;  Yang, Ruirui;  Hou, Hui
  |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17
A comprehensive analysis of the Bencao (herbal) small RNA Atlas reveals novel RNA therapeutics for treating human diseases 期刊论文  OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 19
作者:  Cao, Yinghao;  Lin, Yexuan;  Sun, Na;  Du, Xinyi;  Dong, Yixin
  |  收藏  |  浏览/下载：25/0  |  提交时间：2023/10/17
Optimization of carbazole carboxamide RORγt agonists: Challenges in improving the metabolic stability and maintaining the agonistic activity 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 251, 页码: 115213
作者:  Sun, Nannan;  Yu, Mingcheng;  Jiang, Zhengyuan;  Yang, Feng;  Lu, Lixue
  |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27
Design, Synthesis, and Evaluation of (R)-8-((Tetrahydrofuran-2-yl)methyl)pyrido[2,3-d]pyrimidin-7-ones as Novel Selective ACK1 Inhibitors to Combat Acquired Resistance to the Third-Generation EGFR Inhibitor 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 17
作者:  Li, Qian;  Zhang, Tao;  Song, Peiran;  Tong, Linjiang;  Feng, Fang
  |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17
Structural Optimization of Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3226-3249
作者:  Li, Chunpu;  Dai, Yang;  Kong, Xiangtai;  Wang, Bao;  Peng, Xia
  |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27
Experimental and kinetic study of high pressure pyrolysis of n dodecane 期刊论文  OAI收割
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS, 2023, 卷号: 170, 页码: 105908
作者:  Li, Yikai;  Zhang, Jiahe;  Li YJ(李昱君);  Zhang DW(张大尉);  Cui NF(崔乃夫)
  |  收藏  |  浏览/下载：13/0  |  提交时间：2023/04/20