中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
国家天文台 [28]
上海药物研究所 [27]
苏州纳米技术与纳米... [21]
广州能源研究所 [10]
自动化研究所 [7]
高能物理研究所 [4]
更多
采集方式
OAI收割 [110]
内容类型
期刊论文 [95]
会议论文 [14]
专利 [1]
发表日期
2024 [7]
2023 [5]
2022 [5]
2021 [4]
2020 [7]
2019 [6]
更多
学科主题
Instrument... [3]
天文学 [3]
Chemistry [1]
Multidisci... [1]
Optics [1]
Physics [1]
更多
筛选
浏览/检索结果:
共110条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Identification and biological evaluation of fused tetrahydroisoquinoline derivatives as Wnt/β-catenin signaling inhibitors to suppress colorectal cancer
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 276, 页码: 16
作者:
Zhou, Jianhui
;
Xu, Beibei
;
Shen, Qianwen
;
Zhang, Zhenwei
;
Hu, Yuting
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/09/26
Key & Oslash
Colorectal cancer
Wnt/ beta-catenin
Hsp90
Tetrahydroisoquinoline
rds
Discovery of Novel Nonpeptidic and Noncovalent Small Molecule 3CL
pro
Inhibitors as anti-SARS-CoV-2 Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12760-12783
作者:
Jiang, Zhidong
;
Feng, Bo
;
Chen, Lu
;
Nie, Tianqing
;
Chen, Shizhao
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/09/26
Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 3286-3290
作者:
Zheng, Miao
;
Feng, Bo
;
Zhang, Yumin
;
Liu, Xin
;
Zhao, Na
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/08/22
Non-covalent PLpro inhibitors
Antiviral activity
Structural-based drug design
Imidazo[4,5-b]pyridine scaffold
Discovery and Optimization of Tetrahydroisoquinoline Derivatives To Enhance Lysosome Biogenesis as Preclinical Candidates for the Treatment of Alzheimer's Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 11, 页码: 8836-8861
作者:
Zhou, Jianhui
;
Wang, Ning
;
Wang, Mengxue
;
Hu, Yuting
;
Zhang, Zhenwei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/07/12
Rh(III)-Catalyzed C-H Activation/Annulation for the Construction of Quinolizinones and Indolizines
期刊论文
OAI收割
ORGANIC LETTERS, 2024, 卷号: 26, 期号: 21, 页码: 4451-4456
作者:
Hou, Xinjiao
;
Wang, Run
;
Fang, Feifei
;
Qu, Zhiyan
;
Zhou, Jianhui
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/06/27
Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:
Li, Yuan
;
Xu, Tingting
;
Zhao, Yue
;
Zhang, Hui
;
Liu, Zesheng
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/05/07
Electrochemical oxidative cyclization of
N
-allylamides for the synthesis of CF
3
-containing benzoxazines and oxazolines
期刊论文
OAI收割
RSC ADVANCES, 2024, 卷号: 14, 期号: 1, 页码: 154-159
作者:
Li, Yutian
;
Wang, Li
;
Zhou, Shengbin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/02/19
Substrate- and Catalyst-Controlled C-H Bond Activation/Annulation for Construction of Pyrido[2,3,4-
de
]quinazolinones and Indolo[1,2-
c
]quinazolinones
期刊论文
OAI收割
ADVANCED SYNTHESIS & CATALYSIS, 2023, 页码: 8
作者:
Hou, Xinjiao
;
Wang, Run
;
Zhou, Jianhui
;
Li, Yuan
;
Li, Jiyuan
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/01/16
C-H bond activation
Fused heterocycles
Rh(III) catalysis
Ru(II) catalysis
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide
Copper-Catalyzed Synthesis of alpha-Keto Amides from Sulfoxonium Ylides
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2023, 页码: 11
作者:
Wang, Xinghua
;
Li, Yazhou
;
Zhao, Naixuan
;
Liu, Hong
;
Zhou, Yu
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17