中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共110条,第1-10条 帮助

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Identification and biological evaluation of fused tetrahydroisoquinoline derivatives as Wnt/β-catenin signaling inhibitors to suppress colorectal cancer 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 276, 页码: 16
作者:  
Zhou, Jianhui;  Xu, Beibei;  Shen, Qianwen;  Zhang, Zhenwei;  Hu, Yuting
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/09/26
Discovery of Novel Nonpeptidic and Noncovalent Small Molecule 3CLpro Inhibitors as anti-SARS-CoV-2 Drug Candidate 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12760-12783
作者:  
Jiang, Zhidong;  Feng, Bo;  Chen, Lu;  Nie, Tianqing;  Chen, Shizhao
  |  收藏  |  浏览/下载:15/0  |  提交时间:2024/09/26
Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 3286-3290
作者:  
Zheng, Miao;  Feng, Bo;  Zhang, Yumin;  Liu, Xin;  Zhao, Na
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/08/22
Discovery and Optimization of Tetrahydroisoquinoline Derivatives To Enhance Lysosome Biogenesis as Preclinical Candidates for the Treatment of Alzheimer's Disease 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 11, 页码: 8836-8861
作者:  
Zhou, Jianhui;  Wang, Ning;  Wang, Mengxue;  Hu, Yuting;  Zhang, Zhenwei
  |  收藏  |  浏览/下载:20/0  |  提交时间:2024/07/12
Rh(III)-Catalyzed C-H Activation/Annulation for the Construction of Quinolizinones and Indolizines 期刊论文  OAI收割
ORGANIC LETTERS, 2024, 卷号: 26, 期号: 21, 页码: 4451-4456
作者:  
Hou, Xinjiao;  Wang, Run;  Fang, Feifei;  Qu, Zhiyan;  Zhou, Jianhui
  |  收藏  |  浏览/下载:22/0  |  提交时间:2024/06/27
Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:  
Li, Yuan;  Xu, Tingting;  Zhao, Yue;  Zhang, Hui;  Liu, Zesheng
  |  收藏  |  浏览/下载:19/0  |  提交时间:2024/05/07
Electrochemical oxidative cyclization of N-allylamides for the synthesis of CF3-containing benzoxazines and oxazolines 期刊论文  OAI收割
RSC ADVANCES, 2024, 卷号: 14, 期号: 1, 页码: 154-159
作者:  
Li, Yutian;  Wang, Li;  Zhou, Shengbin
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/02/19
Substrate- and Catalyst-Controlled C-H Bond Activation/Annulation for Construction of Pyrido[2,3,4-de]quinazolinones and Indolo[1,2-c]quinazolinones 期刊论文  OAI收割
ADVANCED SYNTHESIS & CATALYSIS, 2023, 页码: 8
作者:  
Hou, Xinjiao;  Wang, Run;  Zhou, Jianhui;  Li, Yuan;  Li, Jiyuan
  |  收藏  |  浏览/下载:20/0  |  提交时间:2024/01/16
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:  
Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu
  |  收藏  |  浏览/下载:23/0  |  提交时间:2024/01/26
Copper-Catalyzed Synthesis of alpha-Keto Amides from Sulfoxonium Ylides 期刊论文  OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2023, 页码: 11
作者:  
Wang, Xinghua;  Li, Yazhou;  Zhao, Naixuan;  Liu, Hong;  Zhou, Yu
  |  收藏  |  浏览/下载:25/0  |  提交时间:2023/10/17