中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Discovery of pyrrolo[2,3-d]pyrimidine derivatives as novel FLT3/ IRAK4 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 23
作者:
Yuan, Haibin
;
Gao, Yue
;
Wang, Peipei
;
Dong, Xiaowu
;
Li, Jia
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
AML
FLT3/IRAK4 inhibitor
Pyrrolo [2,3-d] pyrimidine
Acquired resistance
Adaptive resistance
Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Arabinogalactan-like polysaccharide isolated from the flowers of
Dendrobium
officinale
regulates the gut microbes and promotes vitamin K1, vitamin A, and vitamin B6 products
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2025, 卷号: 366, 页码: 13
作者:
Jin, Can
;
Li, Meixia
;
Duo, Lana
;
Chen, Huixian
;
Guo, Xiaozhen
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Dendrobium officinale
Polysaccharide
Arabinogalactan
Bacteroides spp.
Vitamin
Design, synthesis and structure-activity relationship studies of novel macrocyclic 2,4-diaminopyrimidines as HPK1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 12
作者:
Wu, Feifei
;
Sun, Jiaqi
;
Xu, Mingyang
;
Li, Huiyu
;
Wei, Jiarui
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Macrocycle
Kinase
Inhibitors
HPK1
Cancer immunotherapy
Human gut
Bifidobacterium longum
subsp.
suillum
is enriched in vitro by a pectic polysaccharide isolated from the flowers of
Lilium lancifolium
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2025, 卷号: 364, 页码: 14
作者:
Li, Meixia
;
Liu, Renjie
;
Wang, Tao
;
Duo, Lana
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Polysaccharides
Lilium lancifolium
Human gut microbiota
Bifidobacterium longum subsp. suillum
Discovery of potent anti-idiopathic pulmonary fibrosis (IPF) agents based on an o-aminopyridinyl alkynyl scaffold
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 15
作者:
Wang, Yang
;
Fan, Wenhui
;
Guo, Yihao
;
Sun, Li
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/08/20
IPF
EMT
Key kinases
Inhibitors
Pantelignans A-F, benzofuran sesquineolignan racemates from the roots and rhizomes of
Pandanus
tectorius:
isolation, chiral resolution, and configurational assignment
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2025, 卷号: 1338, 页码: 8
作者:
Huang, Yuepei
;
Chen, Jieting
;
Liu, Zhilong
;
Peng, Lihua
;
Qiao, Weilin
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2025/06/23
Pandanus tectorius
Benzofuran sesquineolignans
Enantiomers
ECD calculations
Targeted characterisation of bioactive prenylated flavonoids from
Ficus
carica
L. fruits
期刊论文
OAI收割
FOOD CHEMISTRY, 2025, 卷号: 483, 页码: 11
作者:
Yuan, Yue
;
Li, Zuopeng
;
Aisa, Haji Akber
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/06/23
Figs
Targeted isolation
Prenylated flavonoids
Antioxidant
Anti-inflammatory
Antitubercular
Recent advances in the synthesis of poly (ADP-ribose)
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 125, 页码: 13
作者:
Wu, Yidan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/06/23
ADP-ribosylation
Poly ADP-ribose
Oligosaccharides
Solid phase synthesis
Pyrophosphate
Discovery of novel imidazo[2,1-b][1,3,4]thiadiazole analogs as fluorescent SHP2 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 10
作者:
Zhang, Chun
;
Yan, Xue
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Cao, Qing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
Imidazo[2,1-b][1,3,4]thiadiazole
Inhibitory activities
Fluorescence imaging
Zebrafish
SHP2