中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [501]
西北高原生物研究所 [56]
昆明植物研究所 [36]
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期刊论文 [1121]
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Distribution, sources, and eco-risk of Current-Use Pesticides (CUPs) in the coastal waters of the northern Shandong Peninsula, China
期刊论文
OAI收割
MARINE POLLUTION BULLETIN, 2024, 卷号: 201, 页码: 9
作者:
Cao, Zhijian
;
Ding, Yunhao
;
Zhang, Lihong
;
Zhang, Jian
;
Liu, Lin
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/23
Current-use pesticides (CUPs)
Shandong Peninsula coastal waters
Seasonal variations
Ecological risk
A truncated test scheme design method for success-failure in-orbit tests
期刊论文
OAI收割
Reliability Engineering and System Safety, 2024, 卷号: 243
作者:
Ding, Wenzhe
;
Bai, Xiang
;
Wang, Qingwei
;
Long, Fang
;
Li, Hailin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/12/07
IOT verification test
Sequential test
Bayesian theory
Risk calculation
Optimization
A novel strategy for treating oncogene-mutated tumors by targeting tumor microenvironment and synergistically enhancing anti-PD-1 immunotherapy
期刊论文
OAI收割
CANCER COMMUNICATIONS, 2024, 页码: 5
作者:
Liu, Yingqiang
;
Tong, Linjiang
;
Zhang, Mengge
;
Zhang, Qi
;
Liu, Qiupei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/13
Metabolic regulation of homologous recombination repair by MRE11 lactylation
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 2, 页码: 40
作者:
Chen, Yuping
;
Wu, Jinhuan
;
Zhai, Linhui
;
Zhang, Tingting
;
Yin, Hui
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
Discovery of a PROTAC degrader for METTL3-METTL14 complex
期刊论文
OAI收割
CELL CHEMICAL BIOLOGY, 2024, 卷号: 31, 期号: 1, 页码: 25
作者:
Du, Wenhao
;
Huang, Yuting
;
Chen, Xiaoai
;
Deng, Yue
;
Sun, Yaoliang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells (vol 41, pg 270, 2020)
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 2
作者:
Chen, Yue-hong
;
Lv, Hao
;
Shen, Ning
;
Wang, Xiao-min
;
Tang, Shuai
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/03/06
Low-Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 17
作者:
Pu, Congying
;
Li, Yize
;
Fu, Yixian
;
Yan, Yiyang
;
Tao, Siyao
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/02/27
AIM2 inflammasome
chemotherapy
gut microbiome
ileal epithelial cells
immune checkpoint blockade
lactobacillus
segmented filamentous bacterium
Discovery of Dual Function Agents That Exhibit Anticancer Activity via Catastrophic Nicotinamide Adenine Dinucleotide Depletion
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16694-16703
作者:
Fu, Yixian
;
Huang, Yahui
;
Zhou, Chenchen
;
Li, Xinge
;
Dong, Guoqiang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/01/26
From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably