中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [16]
地理科学与资源研究所 [3]
力学研究所 [1]
西北高原生物研究所 [1]
自动化研究所 [1]
新疆天文台 [1]
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采集方式
OAI收割 [24]
内容类型
期刊论文 [24]
发表日期
2023 [24]
学科主题
Engineerin... [1]
Environmen... [1]
Science & ... [1]
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浏览/检索结果:
共24条,第1-10条
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发表日期:2023
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Discovery of Dual Function Agents That Exhibit Anticancer Activity via Catastrophic Nicotinamide Adenine Dinucleotide Depletion
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16694-16703
作者:
Fu, Yixian
;
Huang, Yahui
;
Zhou, Chenchen
;
Li, Xinge
;
Dong, Guoqiang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Stretchable Electronic Facial Masks for Skin Electroporation
期刊论文
OAI收割
ADVANCED FUNCTIONAL MATERIALS, 2023, 页码: 14
作者:
Xu XK(徐新凯)
;
Guo L(郭亮)
;
Liu, Hao
;
Zhou ZX(周赞鑫)
;
Li, Shuang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/01
conductive ink
conductive silicone
skin electroporation
stretchable electronics
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:
Wang, Pingyuan
;
Zhu, Wen-Ting
;
Wang, Yajing
;
Song, Shan-Shan
;
Xi, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2023/10/17
PARP1 inhibitor
Synthetic lethality
Drug resistance
Anticancer
Structure -activity relationship
Design and synthesis of 1H-pyrazolo[3,4-
d
]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18
作者:
Zhang, Junjie
;
Li, Yan
;
Tang, Haotian
;
Zhou, Qianqian
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Cancer immunotherapy
HPK1
Structure -based design
HPK1 inhibitor
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors
ProxyMix: Proxy-based Mixup training with label refinery for source-free domain adaptation
期刊论文
OAI收割
NEURAL NETWORKS, 2023, 卷号: 167, 页码: 92-103
作者:
Ding, Yuhe
;
Sheng, Lijun
;
Liang, Jian
;
Zheng, Aihua
;
He, Ran
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/11/16
Source-free unsupervised domain
adaptation
Pseudo labeling
Vegetation structural shift tells environmental changes on the Tibetan Plateau over 40 years
期刊论文
OAI收割
SCIENCE BULLETIN, 2023, 卷号: 68, 期号: 17, 页码: 1928-1937
作者:
Wang, Yanfen
;
Xue, Kai
;
Hu, Ronghai
;
Ding, Boyang
;
Zeng, Hong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/30
Vegetation structural shift
Climate change
The Tibetan Plateau
Vegetation map
Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16
作者:
Chen, Yun
;
Ning, Yi
;
Chen, Zhiwei
;
Xue, Yaping
;
Wu, Qingyun
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Apoptosis
Diffuse large B-Cell lymphoma
Interleukin-1 receptor associated kinase 4
Structure-based drug design
2
3-Dihydrobenzofuran