中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
过程工程研究所 [2]
合肥物质科学研究院 [2]
半导体研究所 [1]
采集方式
OAI收割 [11]
内容类型
期刊论文 [11]
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2022 [1]
2021 [2]
2020 [1]
2019 [1]
2018 [2]
2017 [2]
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The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 229, 页码: 22
作者:
Li, Xiaokang
;
Li, Jinwen
;
Huang, Yunyuan
;
Gong, Qi
;
Fu, Yan
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/06/15
Alzheimer's disease
Depression
Comorbidity
Multi-target-directed ligands
Supramolecular nanozymes based on peptide self-assembly for biomimetic catalysis
期刊论文
OAI收割
NANO TODAY, 2021, 卷号: 41, 页码: 19
作者:
Han, Jingjing
;
Gong, Haoning
;
Ren, Xiaokang
;
Yan, Xuehai
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/06/15
Peptide
Cofactors
Self-assembly
Supramolecular Nanozymes
Biocatalysis
Wavelength-Tunable OTDR for DWDM-PON Based on Optimized Wavelet Denoising
期刊论文
OAI收割
IEEE PHOTONICS TECHNOLOGY LETTERS, 2021, 卷号: 33, 期号: 24, 页码: 1347-1350
作者:
Gong, Ping
;
Jiang, Xiaokang
;
Zhou, Jian
;
Xie, Liang
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/03/23
Repurposing antimycotic ciclopirox olamine as a promising anti-ischemic stroke agent
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 3, 页码: 434-446
作者:
Feng, Hongxuan
;
Hu, Linghao
;
Zhu, Hongwen
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Blood-brain barrier
Brain ischemia
Cell cycle
Inflammation
Neuroprotection
Effects of Impurities on CaSO4 Crystallization in the Ca(H2PO4)(2)-H2SO4-H3PO4-H2O System
期刊论文
OAI收割
ACS OMEGA, 2019, 卷号: 4, 期号: 7, 页码: 12702-12710
作者:
Mu, Xinru
;
Zhu, Ganyu
;
Li, Xu
;
Li, Shaopeng
;
Gong, Xiaokang
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/10/18
Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 12, 页码: 3117-3125
作者:
Liu, Wenwen
;
Wang, Huan
;
Li, Xiaokang
;
Xu, Yixiang
;
Zhang, Jian
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Depression
Cognitive impairment
Multitarget-directed ligand
5-HT1A agonist
5-HT reuptake inhibition
ChE inhibition
Novel Tadalafil Derivatives Ameliorates Scopolamine-Induced Cognitive Impairment in Mice via Inhibition of Acetyicholinesterase (AChE) and Phosphodiesterase 5 (PDE5)
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 7, 页码: 1625-1636
作者:
Ni, Wei
;
Wang, Huan
;
Li, Xiaokang
;
Zheng, Xinyu
;
Wang, Manjiong
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
Multifunctional agents
AChE inhibitors
PDE5 inhibitors
Alzheimer's disease
Novel Vilazodone Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 12, 页码: 2708-2721
作者:
Li, Xiaokang
;
Wang, Huan
;
Xu, Yixiang
;
Liu, Wenwen
;
Gong, Qi
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Alzheimer's disease
depression
multitarget-directed ligand
ChE inhibition
5-HT1A agonist
5-HT reuptake inhibition
Distinguishing faceted oxide nanocrystals with O-17 solid-state NMR spectroscopy
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2017, 卷号: 8, 期号: 无, 页码: 1-6
作者:
Li, Yuhong
;
Wu, Xin-Ping
;
Jiang, Ningxin
;
Lin, Ming
;
Shen, Li
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2017/12/26
Levo-tetrahydropalmatine, a natural, mixed dopamine receptor antagonist, inhibits methamphetamine self-administration and methamphetamine-induced reinstatement
期刊论文
OAI收割
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2016, 卷号: 144, 页码: 67-72
作者:
Gong, Xiaokang
;
Yue, Kai
;
Ma, Baomiao
;
Xing, Junqiao
;
Gan, Yongping
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2019/01/08
Levo-tetrahydropalmatine
Methamphetamine
Dopamine
Antagonist
Self-administration
Reinstatement