机构

• 上海药物研究所 [8]

采集方式

• OAI收割 [8]

内容类型

• 期刊论文 [8]

发表日期

• 2022 [1]
• 2021 [1]
• 2019 [1]
• 2018 [2]
• 2017 [2]
• 2014 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共8条，第1-8条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 13 作者:  Luo, Menglan;  Wu, Qian;  Yang, Yueyue;  Sun, Lin;  Huan, Xiajuan   |  收藏  |  浏览/下载：55/0  |  提交时间：2022/08/30 BET inhibitor  BRD4  Bivalent inhibitor  Anticancer   Discovery of a series of 1H-pyrrolo[2,3-b]pyridine compounds as potent TNIK inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 33, 页码: 127749 作者:  Yang, Bowen;  Wu, Qian;  Huan, Xiajuan;  Wang, Yingqing;  Sun, Yin   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/03/21 TNIK inhibitor  1H-pyrrolo[2,3-b]pyridine  IL-2 secretion inhibitory   Metal-free quinolylation of the primary amino groups of amino acid derivatives and peptides with dihydrooxazolo[3,2-a]quinoliniums 期刊论文  OAI收割 GREEN CHEMISTRY, 2019, 卷号: 21, 期号: 15, 页码: 4231-4237 作者:  Liu, Peng;  Li, Bo;  Xi, Mengyu;  Chen, Zhaoqiang;  Sun, Haiguo   |  收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01 Three New Cytotoxic Monoterpenoid Bisindole Alkaloids from Tabernaemontana bufalina 期刊论文  OAI收割 PLANTA MEDICA, 2018, 卷号: 84, 期号: 15, 页码: 1127-1133 作者:  Zhou, Si-Yuan;  Zhou, Ting-Lan;  Qiu, Guofu;  Huan, Xiajuan;  Miao, Ze-Hong   |  收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Tabernaemontana bufalina  Apocynaceae  monoterpenoid indole alkaloids  cytotoxicity   Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 389-403 作者:  Chen, Xuxing;  Huan, Xiajuan;  Liu, Qiufeng;  Wang, Yuqin;  He, Qian   |  收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 PARP1/2 inhibitor  Benzimidazole  4,5,6,7-Tetrahydrothienopyridine  Co-crystal structure  Isothermal Titration Calorimetry   Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531 作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang   |  收藏  |  浏览/下载：41/0  |  提交时间：2019/01/08 Antitumor drug  BRCA1/2  PARP inhibitors  Molecular docking   discoveryofpotent24difluorolinkerpolyadpribosepolymerase1inhibitorswithenhancedwatersolubilityandinvivoanticancerefficacy 期刊论文  OAI收割 actapharmacologicasinica, 2017, 卷号: 38, 期号: 11, 页码: 1521 作者:  Chen Wenhua;  Song Shanshan;  Ql Minghui;  Huan Xiajuan;  Wang Yingqing   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 PARP INHIBITORS  MEDICINAL CHEMISTRY  DRUG DISCOVERY  CANCER  THERAPY  DESIGN  FLUORINE  SUCCESS  PREDICT  METRICS  PARP-1 inhibitor  olaparib  breast cancer  BRCA-deficient tumors   Synthesis of isoquinolinone-based tricycles as novel poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 12, 页码: 2669-2673 作者:  Chen, Jianyang;  Peng, Haixia;  He, Jinxue;  Huan, Xiajuan;  Miao, Zehong   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 Isoquinolinone-based tricycles  PARP-1 inhibitors  Antitumor