中国科学院机构知识库网格
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Exploring Origin-Dependent Susceptibility of Smooth Muscle Cells to Aortic Diseases Through Intersectional Genetics
期刊论文
OAI收割
CIRCULATION, 2025, 卷号: 151, 期号: 17, 页码: 1248-1267
作者:
Han, Ximeng
;
Li, Yi
;
Wang, Enci
;
Zhu, Huan
;
Huang, Xiuzhen
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/06/23
aortic diseases
developmental origin
lineage tracing
smooth muscle cell
TGF-beta
Broadband γ-Ray Spectrum of Supernova Remnant Cassiopeia A
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 982, 期号: 1
作者:
Cao, Zhen
;
Aharonian, F.
;
Bai, Y. X.
;
Bao, Y. W.
;
Bastieri, D.
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/05/05
Constraining the Cosmic-Ray Energy Based on Observations of Nearby Galaxy Clusters by LHAASO
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 982, 期号: 1
作者:
Cao, Zhen
;
Aharonian, F.
;
Bai, Y. X.
;
Bao, Y. W.
;
Bastieri, D.
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/05/05
AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
He, Xin-heng
;
Li, Jun-rui
;
Shen, Shi-yi
;
Xu, H. Eric
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/01/14
AlphaFold
structure-based drug design
artificial intelligence
GPCR
structural biology
Synergism of salvianolic acid B and ginsenoside Rg1 magnifies the therapeutic potency against ischemic stroke
期刊论文
OAI收割
NEUROREPORT, 2024, 卷号: 35, 期号: 16, 页码: 1041-1051
作者:
Shen, Haishang
;
Zhang, Yuhan
;
Shao, Yanan
;
Chen, Siqi
;
Yin, Ping
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/11/26
Bliss independence statistical model
ginsenoside Rg1
glycerophospholipid metabolism
ischemic stroke
salvianolic acid B
synergistic effect
Design, Synthesis, and Biological Evaluation of HDAC Inhibitors Containing Natural Product-Inspired
N
-Linked 2-Acetylpyrrole Cap
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 19, 页码: 26
作者:
Zhang, Han
;
Shen, Qianqian
;
Hu, Zhu
;
Wu, Pei-Qian
;
Chen, Yi
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/11/26
HDAC inhibitors
anti-cancer activity
natural products
pyrrole derivatives
molecular docking
molecular dynamics simulation
AI-driven antibody design with generative diffusion models: current insights and future directions
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
He, Xin-heng
;
Li, Jun-rui
;
Xu, James
;
Shan, Hong
;
Shen, Shi-yi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/11/05
antibodies
generative model
diffusion
de novo antibody design
CDR optimization
model evaluation
Redefinition of the Global Stratotype Section and Point (GSSP) and new Standard Auxiliary Boundary Stratotype (SABS) for the base of Wuchiapingian Stage (Lopingian Series, Permian) in South China
期刊论文
OAI收割
EPISODES, 2024, 卷号: 47, 期号: 1, 页码: 147-177
作者:
Shen, Shu-zhong
;
Yuan, Dong-xun
;
Zhang, Yi-chun
;
Henderson, Charles M.
;
Zheng, Quan-feng
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/10/10
Redefinition of the Global Stratotype Section and Point (GSSP) and new Standard Auxiliary Boundary Stratotype (SABS) for the base of Wuchiapingian Stage (Lopingian Series, Permian) in South China
期刊论文
OAI收割
EPISODES, 2024, 卷号: 47, 期号: 1, 页码: 147-177
作者:
Shen, Shu-zhong
;
Yuan, Dong-xun
;
Zhang, Yi-chun
;
Henderson, Charles M.
;
Zheng, Quan-feng
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/03/28
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects