机构

• 上海药物研究所 [14]

采集方式

• OAI收割 [14]

内容类型

• 期刊论文 [14]

发表日期

• 2025 [3]
• 2024 [5]
• 2022 [1]
• 2021 [1]
• 2020 [2]
• 2019 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共14条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11 作者:  Guma, Samuel Desta;  Song, Kang;  Sun, Haiguo;  Yang, Lei   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/08/20 SARS-CoV-2  3CL(pro) inhibitors  Thioamide derivatives  Spiropyrrolidine derivatives  Nirmatrelvir  HCoV-OC43  Antiviral  Metabolic stability   Identification of Cannabigerol-Derived Dual CB2 Receptor Agonists and TRPM8 Antagonists with Anti-Inflammatory and Analgesic Activities 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 13, 页码: 13335-13357 作者:  Yang, Wenjiao;  Sun, Haiguo;  Ji, Jing;  Chen, Hai;  Cheng, Jiaxin   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/08/20 Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796 作者:  Hu, Liuyan;  Zhao, Zhi;  Zhang, Shujing;  Yang, Lei;  Cui, Wenjie   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/06/23 COVID-19  SARS-CoV-2  3CL protease  Peptidomimetic inhibitors  Tetrahydropyrrole spirodihydroindolone   Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 112, 页码: 5 作者:  Shen, Wen;  Chen, Xinyao;  Zhou, Liping;  Cheng, Yan;  Zhang, Yan   |  收藏  |  浏览/下载：46/0  |  提交时间：2024/10/21 COVID-19  SARS-CoV-2 3CL pro inhibitor  Drug design  Antiviral activities   Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 111, 页码: 16 作者:  Li, Xiaomei;  Zhang, Hui;  Dong, Sanfeng;  Gao, Xuejie;  Sun, Haiguo   |  收藏  |  浏览/下载：43/0  |  提交时间：2024/09/26 Multiple myeloma  1-amido-2-one-4-thio-deoxypyranose  TRIP13 inhibitor  In vivo activity   Direct esterification of amides by the dimethylsulfate-mediated activation of amide C-N bonds 期刊论文  OAI收割 COMMUNICATIONS CHEMISTRY, 2024, 卷号: 7, 期号: 1, 页码: 9 作者:  Qin, Hongjian;  Han, Zijian;  Bonku, Emmanuel Mintah;  Sun, Haiguo;  Odilov, Abdullajon   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/05/31 Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20 作者:  Yang, Wenjiao;  Gong, Xudong;  Sun, Haiguo;  Wu, Chunhui;  Suo, Jin   |  收藏  |  浏览/下载：33/0  |  提交时间：2024/03/06 CB2R agonist  5-HT1AR agonist  CB1R antagonist  Antidepressant  Anxiolytic   Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7 作者:  Dong, Sanfeng;  Hu, Ke;  Shi, Yulong;  Wang, Guanli;  Yu, Dandan   |  收藏  |  浏览/下载：38/0  |  提交时间：2024/02/19 Multiple myeloma  TRIP13 inhibitor  Cantharidin  DCZ5418  DCZ0415   Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 14 作者:  Sun, Haiguo;  Xi, Mengyu;  Jin, Qiang;  Zhu, Zhengdan;  Zhang, Yani   |  收藏  |  浏览/下载：67/0  |  提交时间：2022/09/30 Discovery of chiral N-2 '-aryletheryl-1 '-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 11 作者:  Li, Bo;  Li, Heng;  Zhu, Zhengdan;  Xiang, Caigui;  Xu, Zhijian   |  收藏  |  浏览/下载：69/0  |  提交时间：2021/11/04 Anti-inflammatory activity  TNF alpha  ER beta  IBD Arylisoquinolones