中国科学院机构知识库网格系统: 检索

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	Design, synthesis and biological evaluation of 2-aminopyrimidine derivatives as potent FLT3 inhibitors 期刊论文 OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 96, 页码: 5 作者: Lian, Xuanmin; Gao, Yue; Li, Xuemei \| 收藏 \| 浏览/下载：19/0 \| 提交时间：2023/12/11 2-aminopyrimidine FLT3 inhibitors MV4-11 FLT3 mutations
	Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities 期刊论文 OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23 作者: Li, Xuemei; Wang, Peipei; Wang, Chang; Jin, Tingting; Xu, Ran \| 收藏 \| 浏览/下载：24/0 \| 提交时间：2023/10/17
	Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia 期刊论文 OAI收割 LEUKEMIA, 2022, 页码: 11 作者: Jiang, Kailong; Li, Xuemei; Wang, Chang; Hu, Xiaobei; Wang, Peipei \| 收藏 \| 浏览/下载：29/0 \| 提交时间：2023/04/10
	Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235 作者: Qu, Bingxue; Xu, Yongjin; Lu, Yang; Zhuang, Weihao; Jin, Xinxin \| 收藏 \| 浏览/下载：43/0 \| 提交时间：2022/12/23 XPO1 Multiple myeloma MM.1S N-phenylsulfonamide Oral administration
	Identification of 2-Aminopyrimidine Derivatives as FLT3 Kinase Inhibitors with High Selectivity over c-KIT 期刊论文 OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 4, 页码: 3229-3248 作者: Tong, Lexian; Wang, Peipei; Li, Xuemei; Dong, Xiaowu; Hu, Xiaobei \| 收藏 \| 浏览/下载：28/0 \| 提交时间：2022/08/16
	Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62 作者: Tong, Lexian; Song, Pinrao; Jiang, Kailong; Xu, Lei; Jin, Tingting \| 收藏 \| 浏览/下载：28/0 \| 提交时间：2020/07/01 CHK1 kinase inhibitor Selectivity Monotherapy Hematologic malignancies