机构

• 上海药物研究所 [10]
• 植物研究所 [4]
• 上海应用物理研究所 [1]
• 工程热物理研究所 [1]

采集方式

• OAI收割 [16]

内容类型

• 期刊论文 [15]
• 会议论文 [1]

发表日期

• 2022 [1]
• 2021 [1]
• 2018 [2]
• 2017 [4]
• 2015 [2]
• 2013 [4]
• 更多

学科主题

• Plant Scie... [2]
• Biochemica... [1]
• Controls, ... [1]

筛选

浏览/检索结果: 共16条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 13 作者:  Luo, Menglan;  Wu, Qian;  Yang, Yueyue;  Sun, Lin;  Huan, Xiajuan   |  收藏  |  浏览/下载：55/0  |  提交时间：2022/08/30 BET inhibitor  BRD4  Bivalent inhibitor  Anticancer   Discovery of a series of 1H-pyrrolo[2,3-b]pyridine compounds as potent TNIK inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 33, 页码: 127749 作者:  Yang, Bowen;  Wu, Qian;  Huan, Xiajuan;  Wang, Yingqing;  Sun, Yin   |  收藏  |  浏览/下载：26/0  |  提交时间：2024/03/21 TNIK inhibitor  1H-pyrrolo[2,3-b]pyridine  IL-2 secretion inhibitory   Structure-based optimization of a series of selective BET inhibitors containing aniline or indoline groups 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 150, 页码: 156-175 作者:  Hu, Jianping;  Wang, Yingqing   |  收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08 BRD4  BI2536  Indoline  WPF binders  c-Myc  PD-L1   Structural Modification of Natural Product Tanshinone I Leading to Discovery of Novel Nitrogen-Enriched Derivatives with Enhanced Anticancer Profile and Improved Drug-like Properties 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 3, 页码: 760-776 作者:  Ding, Chunyong;  Tian, Qianting;  Li, Jie;  Jiao, Mingkun;  Song, Shanshan   |  收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531 作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang   |  收藏  |  浏览/下载：41/0  |  提交时间：2019/01/08 Antitumor drug  BRCA1/2  PARP inhibitors  Molecular docking   Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 176-195 作者:  Hu, Jianping;  Wang, Yingqing;  Li, Yanlian;  Xu, Lin;  Cao, Danyan   |  收藏  |  浏览/下载：47/0  |  提交时间：2019/01/08 BRD4 inhibitor  Kinase  BI-2536  Dihydroquinoxalin-2(1H)-one   Low, but not high, dose caffeine is a readily available probe for adenosine actions 期刊论文  OAI收割 MOLECULAR ASPECTS OF MEDICINE, 2017, 卷号: 55, 页码: 20-25 作者:  Fredholm, Bertil B.;  Yang, Jiangning;  Wang, Yingqing   |  收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 Adenosine  Caffeine  Theophylline  Heart rate  Locomotion   discoveryofpotent24difluorolinkerpolyadpribosepolymerase1inhibitorswithenhancedwatersolubilityandinvivoanticancerefficacy 期刊论文  OAI收割 actapharmacologicasinica, 2017, 卷号: 38, 期号: 11, 页码: 1521 作者:  Chen Wenhua;  Song Shanshan;  Ql Minghui;  Huan Xiajuan;  Wang Yingqing   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 PARP INHIBITORS  MEDICINAL CHEMISTRY  DRUG DISCOVERY  CANCER  THERAPY  DESIGN  FLUORINE  SUCCESS  PREDICT  METRICS  PARP-1 inhibitor  olaparib  breast cancer  BRCA-deficient tumors   Fragment-Based Drug Discovery of 2-Thiazolidinones as BRD4 Inhibitors: 2. Structure-Based Optimization 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 58, 期号: 3, 页码: 1281-1297 作者:  Zhao, Lele;  Wang, Yingqing;  Cao, Danyan;  Chen, Tiantian;  Wang, Qi   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Characterization of the cis elements in the proximal promoter regions of the anthocyanin pathway genes reveals a common regulatory logic that governs pathway regulation 期刊论文  OAI收割 JOURNAL OF EXPERIMENTAL BOTANY, 2015, 卷号: 66, 期号: 13, 页码: 3775-3789 作者:  Zhu, Zhixin;  Wang, Hailong;  Wang, Yiting;  Guan, Shan;  Wang, Fang   |  收藏  |  浏览/下载：33/0  |  提交时间：2022/09/13 Anthocyanin pathway  Arabidopsis  bHLH  cis element  Ipomoea  MBW complex  MYB  promoter activity  promoter architecture  regulatory module  trans factor  transcription initiation  WDR