中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
广州生物医药与健康研... [5]
上海药物研究所 [3]
过程工程研究所 [1]
合肥物质科学研究院 [1]
采集方式
OAI收割 [10]
内容类型
期刊论文 [10]
发表日期
2023 [1]
2022 [1]
2020 [1]
2017 [1]
2010 [1]
2008 [5]
更多
学科主题
Chemistry [2]
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Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 14
作者:
Liu, Jiayuan
;
Zhang, Xianglei
;
Chen, Guofeng
;
Shao, Qiang
;
Zou, Yi
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2024/01/16
Phosphodiesterase-4 (PDE4)
PDE5
Inhibitor
Drug repurposing
Crystal structure
Structure -guided optimization
Structure-based design of a novel inhibitor of the ZIKA virus NS2B/ NS3 protease
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 7
作者:
Xiong, Yanchao
;
Cheng, Fei
;
Zhang, Junyi
;
Su, Haixia
;
Hu, Hangchen
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/11/11
Zika virus
Fragment -based hit screening
Protein -inhibitor interactions
NS2B
NS3 protease
Crystal structure
Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4090-4106
作者:
Su, Haixia
;
Zou, Yi
;
Chen, Guofeng
;
Dou, Huixia
;
Xie, Hang
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Development of a wideband amplifier for cryogenic scanning tunneling microscopy
期刊论文
OAI收割
REVIEW OF SCIENTIFIC INSTRUMENTS, 2017, 卷号: 88, 期号: 6, 页码: 1-3
作者:
Zhang, Chao
;
Jeon, Hoyeon
;
Oh, Myungchul
;
Lee, Minjun
;
Kim, Sungmin
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2018/06/04
The MicroArray Quality Control (MAQC)-IIII study of common practices for the development and validation of microarray-based predictive models
期刊论文
OAI收割
NATURE BIOTECHNOLOGY, 2010, 卷号: 28, 期号: 8, 页码: 827-U109
作者:
Shi, Leming
;
Campbell, Gregory
;
Jones, Wendell D.
;
Campagne, Fabien
;
Wen, Zhining
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2013/11/15
GENE-EXPRESSION DATA
CONTROL MAQC PROJECT
MULTIPLE-MYELOMA
BREAST-CANCER
PUBLISHED MICROARRAY
FOLLICULAR LYMPHOMA
RISK-STRATIFICATION
DNA MICROARRAYS
CLASSIFICATION
PERFORMANCE
An efficient method for the synthesis of disubstituted thioureas via the reaction of N,N '-di-Boc-substituted thiourea with alkyl and aryl amines under mild conditions
期刊论文
OAI收割
TETRAHEDRON LETTERS, 2008, 卷号: 49, 期号: 22, 页码: 3687-3690
作者:
Yi, Minjun
;
Yin, Biaolin
;
Liu, Zhaogui
;
Zhang, Jiancun
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2018/12/13
An efficient method for the synthesis of disubstituted thioureas via the reaction of N,N '-di-Boc-substituted thiourea with alkyl and aryl amines under mild conditions
期刊论文
OAI收割
TETRAHEDRON LETTERS, 2008, 卷号: 49, 期号: 22, 页码: 3687-3690
Yin, Biaolin
;
Liu, Zhaogui
;
Yi, Minjun
;
Zhang, Jiancun
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2016/12/16
An efficient method for the synthesis of disubstituted thioureas via the reaction of N,N '-di-Boc-substituted thiourea with alkyl and aryl amines under mild conditions
期刊论文
OAI收割
TETRAHEDRON LETTERS, 2008, 卷号: 49, 期号: 22, 页码: 3687-3690
作者:
Yin, Biaolin
;
Liu, Zhaogui
;
Yi, Minjun
;
Zhang, Jiancun
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2018/12/13
An efficient method for the synthesis of disubstituted thioureas via the reaction of N,N '-di-Boc-substituted thiourea with alkyl and aryl amines under mild conditions
期刊论文
OAI收割
TETRAHEDRON LETTERS, 2008, 卷号: 49, 期号: 22, 页码: 3687-3690
作者:
Liu, Zhaogui
;
Zhang, Jiancun
;
Yi, Minjun
;
Yin, Biaolin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2018/12/21
An efficient method for the synthesis of disubstituted thioureas via the reaction of N,N '-di-Boc-substituted thiourea with alkyl and aryl amines under mild conditions
期刊论文
OAI收割
TETRAHEDRON LETTERS, 2008, 卷号: 49, 期号: 22, 页码: 3687-3690
作者:
Zhang, Jiancun
;
Yin, Biaolin
;
Yi, Minjun
;
Liu, Zhaogui
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2018/12/13