中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [15]
金属研究所 [3]
长春光学精密机械与物... [3]
光电技术研究所 [3]
自动化研究所 [3]
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OAI收割 [41]
内容类型
期刊论文 [38]
学位论文 [3]
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2024 [1]
2023 [1]
2022 [4]
2021 [3]
2020 [4]
2019 [6]
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Biochemist... [1]
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Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:
Qin, Ying
;
Li, Dekang
;
Qi, Chunting
;
Xiang, Huaijiang
;
Meng, Huyan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/03/06
RIPK1
Necroptosis
Type-II kinase inhibitors
Rational design
Lead optimization
Structure-activity relationship
Anti-inflammation
Preclinical drug discovery
Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 14
作者:
Liu, Jiayuan
;
Zhang, Xianglei
;
Chen, Guofeng
;
Shao, Qiang
;
Zou, Yi
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/01/16
Phosphodiesterase-4 (PDE4)
PDE5
Inhibitor
Drug repurposing
Crystal structure
Structure -guided optimization
A Self-Attention-Based Deep Reinforcement Learning Approach for AGV Dispatching Systems
期刊论文
OAI收割
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS, 2022, 页码: 12
作者:
Wei, Qinglai
;
Yan, Yutian
;
Zhang, Jie
;
Xiao, Jun
;
Wang, Cong
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2023/01/09
Automated guided vehicle (AGV) dispatching
deep learning
reinforcement learning (RL)
self-attention
Land use optimization in Ningbo City with a coupled GA and PLUS model
期刊论文
OAI收割
JOURNAL OF CLEANER PRODUCTION, 2022, 卷号: 375, 页码: 13
作者:
Li, Xiang
;
Fu, Jingying
;
Jiang, Dong
;
Lin, Gang
;
Cao, Chenglong
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/11/09
SDGs
Production -living -ecological land
Function identification
Overall optimization
GA -PLUS model
Evolution of Controllers Under a Generalized Structure Encoding/Decoding Scheme With Application to Magnetic Levitation System
期刊论文
OAI收割
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS, 2022, 卷号: 69, 期号: 9, 页码: 9655-9666
作者:
Xin, Bin
;
Wang, Yipeng
;
Xue, Wenchao
;
Cai, Tao
;
Fan, Zhun
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/06/21
Optimization
Design methodology
Control systems
Tuning
Magnetic levitation
Signal processing
Periodic structures
Automatic design of controllers
disturbance-rejection
intelligent optimization algorithms
magnetic levitation system (MLS)
mixed-variable optimization
Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1)
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 3, 页码: 2174-2190
作者:
Liu, Liping
;
Zhu, Rui
;
Li, Jiacheng
;
Pei, Yuan
;
Wang, Shuangshuang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/08/16
The Slope-Attribute-Regularized High-Resolution Prestack Seismic Inversion
期刊论文
OAI收割
SURVEYS IN GEOPHYSICS, 2021, 页码: 47
作者:
Huang, Guangtan
;
Chen, Xiaohong
;
Li, Jingye
;
Saad, Omar M.
;
Fomel, Sergey
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/05/25
Seismic slope
Prestack AVA inversion
Starting model
Directional total variation
Integrating data mining and machine learning to discover high-strength ductile titanium alloys
期刊论文
OAI收割
ACTA MATERIALIA, 2021, 卷号: 202, 页码: 211-221
作者:
Zou, Chengxiong
;
Li, Jinshan
;
Wang, William Yi
;
Zhang, Ying
;
Lin, Deye
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/03/15
High-throughput calculation
Machine learning
Electron work function
Similar atomic environment
Bonding charge density
Saliency detection with bilateral absorbing markov chain guided by depth information
期刊论文
OAI收割
Sensors (Switzerland), 2021, 卷号: 21, 期号: 3, 页码: 1-23
作者:
J. Wu
;
G. Han
;
P. Liu
;
H. Yang
;
H. Luo and Q. Li
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2022/06/13
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:
Bi, Xiaoyang
;
Chen, Yu
;
Sun, Zhongya
;
Lu, Wenchao
;
Xu, Pan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Drug design
CBP
Bromodomain
Inhibitor
Acute myeloid leukemia