中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d] pyrimidines as potent HPK1 kinase inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 119, 页码: 13
作者:
Wu, Feifei
;
Li, Huiyu
;
Li, Weiqiang
;
Zhang, Laishun
;
An, Qi
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/04/01
Optimization
Hematopoietic progenitor kinase 1
Inhibitor
Cancer immunotherapy
Discovery of an Efficacious RET PROTAC Degrader with Enhanced Antiproliferative Activity against Resistant Cancer Cells Harboring RET Solvent-Front Mutations
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 68, 期号: 1, 页码: 753-775
作者:
Zhang, Qian
;
He, Yingqi
;
Rao, Danni
;
He, Rui
;
Yu, Lei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/02/28
Population genomic analysis reveals a polygenic sex determination system in
Apostichopus japonicus
期刊论文
OAI收割
ISCIENCE, 2024, 卷号: 27, 期号: 10, 页码: 16
作者:
Jiang, Chunxi
;
Liu, Shilin
;
Yang, Yujia
;
Cui, Wei
;
Xu, Shuai
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/12/20
Importance of the ECM-receptor interaction for adaptive response to hypoxia based on integrated transcription and translation analysis
期刊论文
OAI收割
MOLECULAR ECOLOGY, 2024, 页码: 19
作者:
Huo, Da
;
Liu, Shilin
;
Zhang, Libin
;
Yang, Hongsheng
;
Sun, Lina
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/06/04
Apostichopus japonicus
ribosome profiling
RNA-seq
transcriptional regulation
translational efficiency
translational regulation
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent
A radiomics and genomics-derived model for predicting metastasis and prognosis in colorectal cancer
期刊论文
OAI收割
CARCINOGENESIS, 2024, 页码: 11
作者:
Li, Xue
;
Wu, Meng
;
Wu, Min
;
Liu, Jie
;
Song, Li
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/03/26
Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 3
作者:
Yu, Lei
;
Zhao, Pengcheng
;
Sun, Yaoliang
;
Zheng, Zening
;
Du, Wenhao
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/01/26
Metabolomic insights into neurological effects of BDE-47 exposure in the sea cucumber Apostichopus japonicus
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 卷号: 266, 页码: 11
作者:
Ding, Kui
;
Xu, Qinzeng
;
Zhang, Xuelei
;
Liu, Shilin
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/04/07
Apostichopus japonicus
BDE-47
Nervous system
UPLC-Triple-TOF-MS
Metabolite
Neurotoxicity
Metabolic profiling of
Apostichopus japonicus
body wall exposed to a typical type of PBDEs: potential health risks and impact on sea cucumber health
期刊论文
OAI收割
FRONTIERS IN MARINE SCIENCE, 2023, 卷号: 10, 页码: 15
作者:
Ding, Kui
;
Zhuo, Pengji
;
Ge, Meiling
;
Liao, Xiaomei
;
Mo, Jing
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/11/30
sea cucumber
BDE-47
body wall
metabolite
metabolic pathway
Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:
Rao, Danni
;
Yang, Tao
;
Feng, Huixu
;
An, Qi
;
Zhang, Shaofeng
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17