中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Design, synthesis and structure-activity relationship studies of novel macrocyclic 2,4-diaminopyrimidines as HPK1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 12
作者:
Wu, Feifei
;
Sun, Jiaqi
;
Xu, Mingyang
;
Li, Huiyu
;
Wei, Jiarui
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Macrocycle
Kinase
Inhibitors
HPK1
Cancer immunotherapy
Solid-state screening and dry powder inhaler development of ziyuglycoside II sodium salt for enhanced bioavailability
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2025, 卷号: 681, 页码: 11
作者:
Zhang, Hanwen
;
Wang, Siwen
;
Slimani, Sara
;
Lv, Yuting
;
Nie, Qin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
Bioavailability
Dry powder inhaler
Saponin
Solid-state screening
Ziyuglycoside II sodium salt
Identification of candidate genes and SNPs associated with growth traits by genome-wide association study (GWAS) in sea cucumber
(Apostichopus
japonicus)
期刊论文
OAI收割
AQUACULTURE, 2025, 卷号: 605, 页码: 10
作者:
Cui, Wei
;
Su, Fang
;
Liu, Shilin
;
Zhang, Libin
;
Yang, Hongsheng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/07/11
Sea cucumber ( Apostichopus japonicus )
Growth traits
GWAS
Genomic selection
Tracheal Targeted Nanogrid Delivery Systems of Dexamethasone Visualized by Single-Particle Tracing and Multiscale Pathological Mapping
期刊论文
OAI收割
ACS NANO, 2025, 卷号: 19, 期号: 25, 页码: 23414-23430
作者:
Cao, Zeying
;
Zhou, Shilin
;
Zhao, Yanli
;
Wu, Qian
;
Huang, Chenxi
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
three-dimensional pathology
nanogrid
ROS-scavenging
tracheal targeted
bronchitis
nano-bio-interactions
Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d] pyrimidines as potent HPK1 kinase inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 119, 页码: 13
作者:
Wu, Feifei
;
Li, Huiyu
;
Li, Weiqiang
;
Zhang, Laishun
;
An, Qi
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/04/01
Optimization
Hematopoietic progenitor kinase 1
Inhibitor
Cancer immunotherapy
Discovery of an Efficacious RET PROTAC Degrader with Enhanced Antiproliferative Activity against Resistant Cancer Cells Harboring RET Solvent-Front Mutations
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 68, 期号: 1, 页码: 753-775
作者:
Zhang, Qian
;
He, Yingqi
;
Rao, Danni
;
He, Rui
;
Yu, Lei
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/02/28
Population genomic analysis reveals a polygenic sex determination system in
Apostichopus japonicus
期刊论文
OAI收割
ISCIENCE, 2024, 卷号: 27, 期号: 10, 页码: 16
作者:
Jiang, Chunxi
;
Liu, Shilin
;
Yang, Yujia
;
Cui, Wei
;
Xu, Shuai
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/12/20
Importance of the ECM-receptor interaction for adaptive response to hypoxia based on integrated transcription and translation analysis
期刊论文
OAI收割
MOLECULAR ECOLOGY, 2024, 页码: 19
作者:
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/06/04
Apostichopus japonicus
ribosome profiling
RNA-seq
transcriptional regulation
translational efficiency
translational regulation
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent
A radiomics and genomics-derived model for predicting metastasis and prognosis in colorectal cancer
期刊论文
OAI收割
CARCINOGENESIS, 2024, 页码: 11
作者:
Li, Xue
;
Wu, Meng
;
Wu, Min
;
Liu, Jie
;
Song, Li
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2024/03/26