机构

• 上海药物研究所 [24]
• 化学研究所 [1]
• 海洋研究所 [1]
• 近代物理研究所 [1]

采集方式

• OAI收割 [27]

内容类型

• 期刊论文 [27]

发表日期

• 2024 [3]
• 2023 [2]
• 2022 [2]
• 2021 [2]
• 2020 [4]
• 2019 [3]
• 更多

学科主题

筛选

浏览/检索结果: 共27条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1318, 页码: 13 作者:  Tang, Mingze;  Zhou, Xuan;  Shen, Qianqian;  Fang, Chen;  Peng, Xia   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/08/22 Receptor -interacting protein kinase 1  Histone deacetylases  Inhibitor  Molecular dynamics (MD) simulation  ADMET analysis   Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors 期刊论文  OAI收割 ARCHIV DER PHARMAZIE, 2024, 页码: 16 作者:  An, Yuxiang;  Peng, Xia;  Wang, Tianchen;  Liu, Kaiyuan;  Feng, Dazhi   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/12/25 inhibitor  pharmacokinetic study  pyridazin-4-one  receptor-interacting protein kinase 1  selectivity   A Novel IRAK4 Inhibitor DW18134 Ameliorates Peritonitis and Inflammatory Bowel Disease 期刊论文  OAI收割 MOLECULES, 2024, 卷号: 29, 期号: 8, 页码: 17 作者:  Huang, Yuqing;  Ning, Yi;  Chen, Zhiwei;  Song, Peiran;  Tang, Haotian   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/05/31 IRAK4 inhibitor  peritonitis  inflammatory bowel disease (IBD)  macrophage   Design, synthesis, and STING-agonistic activity of benzo[b]thiophene-2-carboxamide derivatives 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2023, 页码: 10 作者:  Zhou, Rongyao;  Wang, Xiyuan;  Zhang, Deqiang;  Zhan, Zhengsheng;  Duan, Wenhu   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/12/08 STING  CDN  Benzo[b]thiophene-2-carboxamide  Cellular activity   Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16 作者:  Chen, Yun;  Ning, Yi;  Chen, Zhiwei;  Xue, Yaping;  Wu, Qingyun   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/10/17 Apoptosis  Diffuse large B-Cell lymphoma  Interleukin-1 receptor associated kinase 4  Structure-based drug design  2  3-Dihydrobenzofuran   Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation 期刊论文  OAI收割 CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 17 作者:  Xie, Zuoquan;  Wang, Zhen;  Fan, Fengying;  Zhou, Jinpei;  Hu, Zhaoxue   |  收藏  |  浏览/下载：37/0  |  提交时间：2023/04/10 Smart drug delivery systems for precise cancer therapy 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 11, 页码: 4098-4121 作者:  Wang, Xiaoyou;  Li, Chong;  Wang, Yiguang;  Chen, Huabing;  Zhang, Xinxin   |  收藏  |  浏览/下载：31/0  |  提交时间：2023/04/10 Pharmaceutics  Smart drug delivery system  Stimuli-responsive  Receptor-ligand-based delivery  Nano-drug delivery systems  Precise therapy  Toxicity  Cancer   Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13 作者:  Chen, Yun;  Bai, Gang;  Li, Yan;  Ning, Yi;  Cao, Sufen   |  收藏  |  浏览/下载：68/0  |  提交时间：2021/12/01 FLT3  FLT3-ITD  Acute myeloid leukemia  Structure-activity relationships  Pyrazolo[1, 5-a]pyrimidine   Design, Synthesis, and Biological Evaluation of IRAK4-Targeting PROTACs 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 1, 页码: 82-87 作者:  Chen, Yun   |  收藏  |  浏览/下载：62/0  |  提交时间：2021/05/24 IRAK4  PROTAC  protein degrader  scaffolding role  diffuse large B-cell lymphoma   Estimating animal population size with very high-resolution satellite imagery 期刊论文  OAI收割 CONSERVATION BIOLOGY, 2020, 页码: 9 作者:  Zhao, Peng;  Liu, Shuming;  Zhou, Yi;  Lynch, Tim;  Lu, Wenhu   |  收藏  |  浏览/下载：37/0  |  提交时间：2021/04/12 population distribution  population size  remote sensing  wildlife management