机构

• 上海药物研究所 [17]
• 水生生物研究所 [3]
• 成都生物研究所 [2]
• 生物物理研究所 [1]
• 中国科学院大学 [1]
• 近代物理研究所 [1]
• 更多

采集方式

• OAI收割 [24]
• iSwitch采集 [1]

内容类型

• 期刊论文 [24]
• 会议论文 [1]

发表日期

• 2024 [3]
• 2023 [3]
• 2022 [1]
• 2020 [2]
• 2019 [5]
• 2018 [4]
• 更多

学科主题

• Biochemist... [1]
• Cell Biolo... [1]
• 天然产物研究 [1]

筛选

浏览/检索结果: 共25条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of PRMT3 Degrader for the Treatment of Acute Leukemia 期刊论文  OAI收割 ADVANCED SCIENCE, 2024, 页码: 8 作者:  Zou, Wanyi;  Li, Mengna;  Wan, Shili;  Ma, Jingkun;  Lian, Linan   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/09/26 acute leukemia  MDM2  oxidative phosphorylation  PRMT3  PROTAC   Excessive fatty acids activate PRMT5/MDM2/Drosha pathway to regulate miRNA biogenesis and lipid metabolism 期刊论文  OAI收割 LIVER INTERNATIONAL, 2024, 页码: 17 作者:  Hou, Aijun;  Xu, Xiaoding;  Zhang, Yu;  He, Hongxiu;  Feng, Yihan   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/05/07 Drosha degradation  lipid metabolism  miRNA biogenesis  NAFLD  PRMT5   Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 19 作者:  Chen, Yuting;  Wang, Zekun;  Zhang, Junjie;  Shi, Qiongyu;  Yang, Hong   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/05/07 PRMT5  Nucleoside derivatives  Methyltransferases  Structure -activity relationship   A patent review of PRMT5 inhibitors to treat cancer (2018-present) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2023, 页码: 28 作者:  Gao, Jing;  Yang, Jie;  Xue, Shengyu;  Ding, Hong;  Lin, Hua   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 PRMT5  inhibitor  epigenetic target  cancer treatment  combined treatment   Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20 作者:  Chen, Yuting;  Shi, Qiongyu;  Yang, Hong;  Li, Jiayi;  Zhou, Kaixin   |  收藏  |  浏览/下载：35/0  |  提交时间：2023/04/10 Epigenetic  PRMT5 inhibitor  Nucleoside derivatives  Structure-activity Relationship Prodrug   PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 1, 页码: 157-173 作者:  Sun, Mingming;  Li, Leilei;  Niu, Yujia;  Wang, Yingzhi;  Yan, Qi   |  收藏  |  浏览/下载：30/0  |  提交时间：2024/03/27 Lung cancer  Metabolic reprogramming  Post-translational modification  PRMT6  Pentose phosphate pathway flux  Glycolysis  6-Phospho-gluconate dehydrogenase  a-enolase  ENO1   Identification of PRMT5 inhibitors with novel scaffold structures through virtual screening and biological evaluations 期刊论文  OAI收割 JOURNAL OF MOLECULAR MODELING, 2022, 卷号: 28, 期号: 7, 页码: 184 作者:  Zhang, Qian;  Zhang, Lun;  Jin, Jia;  Fan, Yaohua;  Wang, Xiaoguang   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/03/21 PRMT5  Small-molecule inhibitors  Virtual screening  Molecular docking  Molecular dynamics simulations   Zebrafishprmt3negatively regulates antiviral responses 期刊论文  OAI收割 FASEB JOURNAL, 2020, 页码: 16 作者:  Zhu, Junji;  Liu, Xing;  Cai, Xiaolian;  Ouyang, Gang;  Zha, Huangyuan   |  收藏  |  浏览/下载：59/0  |  提交时间：2020/11/27 GCRV  innate immunity  prmt3  SVCV  zebrafish   Zebrafish prmt7 negatively regulates antiviral responses by suppressing the retinoic acid-inducible gene-I-like receptor signaling 期刊论文  OAI收割 FASEB JOURNAL, 2020, 卷号: 34, 期号: 1, 页码: 988-1000 作者:  Zhu, Junji;  Liu, Xing;  Cai, Xiaolian;  Ouyang, Gang;  Fan, Sijia   |  收藏  |  浏览/下载：38/0  |  提交时间：2020/05/13 GCRV  irf3  Prmt7  SVCV  zebrafish   Zebrafish prmt5 arginine methyltransferase is essential for germ cell development 期刊论文  OAI收割 DEVELOPMENT, 2019, 卷号: 146, 期号: 20, 页码: 16 作者:  Zhu, Junji;  Zhang, Dawei;  Liu, Xing;  Yu, Guangqing;  Cai, Xiaolian   |  收藏  |  浏览/下载：38/0  |  提交时间：2020/05/08 Germ cell  Prmt5  Zebrafish  Zili  Ziwi  Vasa