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	Design, synthesis, and biological profiling of novel aryl-spirocyclic diamine derivatives with potential antidepressant-like properties 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 301, 页码: 23 作者: Zheng, Jiefang; Tian, Yaxin; Cheng, Jiaxin; Hu, Zhengtao; Zhang, Junchi \| 收藏 \| 浏览/下载：4/0 \| 提交时间：2025/12/04 Antidepressants Multimodal monoaminergic compounds Triple monoamine reuptake inhibitors 5-HT 3A R antagonist Aryl-spirocyclic diamine derivatives
	Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 16 作者: Zheng, Jiefang; Zhou, Liping; Gong, Xudong; Yang, Feipu; Cheng, Jiaxin \| 收藏 \| 浏览/下载：70/0 \| 提交时间：2024/08/22 Triple reuptake inhibitors 5-HT 1A R agonists Antidepressants Multimodal serotonergic compounds
	Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment 期刊论文 OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 12, 页码: 3117-3125 作者: Liu, Wenwen; Wang, Huan; Li, Xiaokang; Xu, Yixiang; Zhang, Jian \| 收藏 \| 浏览/下载：64/0 \| 提交时间：2019/01/08 Depression Cognitive impairment Multitarget-directed ligand 5-HT1A agonist 5-HT reuptake inhibition ChE inhibition
	Novel Vilazodone Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation 期刊论文 OAI收割 ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 12, 页码: 2708-2721 作者: Li, Xiaokang; Wang, Huan; Xu, Yixiang; Liu, Wenwen; Gong, Qi \| 收藏 \| 浏览/下载：62/0 \| 提交时间：2019/01/08 Alzheimer's disease depression multitarget-directed ligand ChE inhibition 5-HT1A agonist 5-HT reuptake inhibition
	Design,synthesis and bioactivity of aryl piperazine benzo[b]oxazine derivatives 期刊论文 OAI收割 Acta Pharmaceutica Sinica, 2012, 卷号: 47, 期号: 6, 页码: 755-763 作者: Zheng Yongyong; Xie Peng; Zhang Jin; Li Jianqi; Guo Lin \| 收藏 \| 浏览/下载：42/0 \| 提交时间：2019/01/08 5-HT_(1A) aryl piperazine benzo [b] oxazine derivatives pharmacophore model 5-HT reuptake 5-HT_(1A)
	Classification of 5-HT_(1A) receptor agonists and antagonists using GA-SVM method 期刊论文 OAI收割 Acta Pharmacologica Sinica, 2011, 卷号: 32, 期号: 11, 页码: 1424 作者: Zhu Xuelian; Cai Haiyan; Xu Zhijian; Wang Yong; Wang Heyao \| 收藏 \| 浏览/下载：51/0 \| 提交时间：2020/07/01 VIVO PHARMACOLOGICAL EVALUATION SEROTONIN TRANSPORTER AFFINITY IN-VITRO DUAL 5-HT1A REUPTAKE INHIBITORS LIGANDS POTENT DERIVATIVES DISCOVERY ANALOGS 5-HT1A receptor support vector machine genetic algorithm agonist antagonists
	Synthesis and biological activities of N-indolalkyl piperidine derivatives and their analogues 期刊论文 OAI收割 Chinese Journal of Medicinal Chemistry, 2009, 卷号: 19, 期号: 3, 页码: 161-169 作者: WANG Guan; ZHANG Gui-sen; GUO Lin; YU Lei-ping; LI Jian-qi \| 收藏 \| 浏览/下载：24/0 \| 提交时间：2019/01/08 N-indolalkyl piperidine derivatives synthesis 5-HT reuptake inhibitors 5-HT_(2A) recepetor non-opioid analgesic activity
	Protopine inhibits serotonin transporter and noradrenaline transporter and has the antidepressant-like effect in mice models 期刊论文 OAI收割 NEUROPHARMACOLOGY, 2006, 卷号: 50, 期号: 8, 页码: 934-940 作者: Xu, Lin-Feng; Chu, Wen-Jing; Qing, Xiao-Yun; Li, Sheng; Wang, Xue-Song \| 收藏 \| 浏览/下载：62/0 \| 提交时间：2019/01/08 Dactylicapnos scandens Hutch antidepressant 5-HT (5-hydroxytryptamine, serotonin) noradrenaline (NE) reuptake inhibitor transporter
	Protopine inhibits serotonin transporter and noradrenaline transporter and has the antidepressant-like effect in mice models 期刊论文 OAI收割 NEUROPHARMACOLOGY, 2006, 卷号: 50, 期号: 8, 页码: 934-940 作者: Xu, LF; Chu, WJ; Qing, XY; Li, S; Wang, XS 收藏 \| 浏览/下载：105/0 \| 提交时间：2015/07/22 Dactylicapnos scandens Hutch antidepressant 5-HT (5-hydroxytryptamine noradrenaline (NE) reuptake inhibitor transporter serotonin)