中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
上海营养与健康研究所 [3]
生物物理研究所 [1]
昆明植物研究所 [1]
中国科学院大学 [1]
昆明动物研究所 [1]
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OAI收割 [12]
iSwitch采集 [1]
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期刊论文 [13]
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2020 [1]
2019 [3]
2018 [3]
2017 [2]
2015 [1]
2013 [1]
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学科主题
Cell Biolo... [2]
Geriatrics... [1]
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AMPK在肿瘤发生发展中的研究现状
期刊论文
OAI收割
中国生物化学与分子生物学报, 2020, 卷号: 36, 期号: 10, 页码: 1165
作者:
董莹
;
臧奕
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/24
AMP-activated protein kinase(AMPK)
metformin
tumorigenesis
energy metabolism
单磷酸腺苷激活的蛋白质激酶
二甲双胍
肿瘤发生
能量代谢
The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:
Wang, Fang
;
Yang, Xiaoyan
;
Lu, Yanting
;
Li, Zhenghui
;
Xu, Yuhui
  |  
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2019/09/10
glucose metabolism
liver kinase B1 (LKB1)
AMP-activated kinase (AMPK)
glucose transporter type 4 (GLUT4)
fungi
Basidiomycete
diabetes
energy sensing
glucose homeostasis
sesquiterpene
Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 3, 页码: 953-967
作者:
Yan, Yan
;
Zhou, X. Edward
;
Novick, Scott J.
;
Shaw, Simon J.
;
Li, Yingwu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
AMP-activated kinase (AMPK)
AMP
hydrogen exchange mass spectrometry
X-ray crystallography
phosphorylation
activation loop phosphorylation
ADaM site
CBS3
R734
R739
metabolic disorder
energy sensor
A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling
期刊论文
OAI收割
CELL STEM CELL, 2019, 卷号: 25, 期号: 1, 页码: 54-+
作者:
Li, Weiping
;
He, Qiang
;
Hu, Chaobo
;
Zhu, Linying
;
Ma, Xiaolong
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/12/09
Berberine
Nonalcoholic fatty liver disease
NAFLD
Stearyl-coenzyme A desaturase 1
SCD1
Sterol regulatory element-binding protein-1c
SREBP-1c
AMP-activated protein kinase
AMPK
Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK)
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 44, 页码: 16994-17007
作者:
Gu, Xin
;
Bridges, Michael D.
;
Yan, Yan
;
de Waal, Parker W.
;
Zhou, X. Edward
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2019/01/08
AMP-activated kinase (AMPK)
biophysics
diabetes
metabolic regulation
cancer
ADaM site
DEER
Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1622-1632
作者:
Zhang, Mei
;
Xie, Zhi-fu
;
Zhang, Run-tao
;
Chen, Da-kai
;
Gu, Min
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/01/08
non-alcoholic fatty liver disease
AMP-activated protein kinase
AMPK activator
homogeneous time-resolved fluorescence
metabolic disorders
ob/ob mice
Age at menarche and age at natural menopause in East Asian women: a genome-wide association study (vol 38, pg 513, 2016)
期刊论文
OAI收割
GEROSCIENCE, 2018, 卷号: 40, 期号: 1, 页码: 71-72
作者:
Shi, Jiajun
;
Zhang, Ben
;
Long, Jirong
;
Wen, Wanqing
;
Cai, Qiuyin
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/12/09
Berberine
Nonalcoholic fatty liver disease
NAFLD
Stearyl-coenzyme A desaturase 1
SCD1
Sterol regulatory element-binding protein-1c
SREBP-1c
AMP-activated protein kinase
AMPK
Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 期号: 30, 页码: 12653-12666
作者:
Gu, Xin
;
Yan, Yan
;
Novick, Scott J.
;
Kovach, Amanda
;
Goswami, Devrishi
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
AMP
AMP-activated kinase (AMPK)
ATP
energy metabolism
protein kinase
CBS
HDX-MS
NADPH
Calcineurin Antagonizes AMPK to Regulate Lipolysis in Caenorhabditis elegans
期刊论文
OAI收割
Molecules, 2017, 卷号: 22, 期号: X, 页码: e1062
作者:
Liang B*
;
Diao ZQ
;
Xie CS
;
Wang YL
;
liangb@mail.kiz.ac.cn
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2017/07/07
Calcineurin
Tacrolimus
Amp-activated Protein Kinase (Ampk)
Triglyceride Lipase Atgl
Lipolysis
Recent research progress in small molecule AMPK direct activators
期刊论文
OAI收割
Journal of China Pharmaceutical University, 2015, 卷号: 46, 期号: 4, 页码: 406-415
作者:
Wei Qiangqiang
;
Duan Wenhu
;
Zhou Jinpei
;
Zhang Huibin
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
AMP-activated protein kinase
AMPK direct activators
structure-activity relationship
type 2 diabetes
new target
advances