机构

• 上海药物研究所 [12]
• 昆明植物研究所 [4]
• 合肥物质科学研究院 [4]
• 上海生物化学与细胞生... [2]
• 计算技术研究所 [1]
• 水生生物研究所 [1]
• 更多

采集方式

• OAI收割 [26]
• iSwitch采集 [1]

内容类型

• 期刊论文 [27]

发表日期

• 2025 [2]
• 2023 [4]
• 2021 [3]
• 2020 [5]
• 2018 [4]
• 2017 [1]
• 更多

学科主题

• Biochemist... [2]
• Genetics &... [2]
• Medicine, ... [2]
• Biochemist... [1]
• Biotechnol... [1]
• Immunology [1]
• 更多

筛选

浏览/检索结果: 共27条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response 期刊论文  OAI收割 EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19 作者:  Yao, Mingyue;  Yan, Wenzhong;  Wang, Yafang;  Zhao, Yu;  Xu, Xiaowei   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/04/01 Acute myeloid leukemia  HDAC inhibitor  FLT3-ITD mutation  DNA damage response  Synergistic effect  Drug resistance   Concurrent inhibition of p300/CBP and FLT3 enhances cytotoxicity and overcomes resistance in acute myeloid leukemia 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 14 作者:  Chen, Yu-jun;  Zhao, Yu;  Yao, Ming-yue;  Wang, Ya-fang;  Ma, Ming   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/04/01 acute myeloid leukemia  FLT3  p300/CBP  quizartinib resistance  combination strategy   Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18 作者:  Zhang, Jingyu;  Duan, Haiting;  Gui, Renzhao;  Wu, Mingfei;  Shen, Liteng   |  收藏  |  浏览/下载：132/0  |  提交时间：2023/12/19 Acute myeloid leukemia  Bromodomain-containing protein 9  Proteolysis-targeting chimera  Orally bioavailable  Docking   Chloroquine enhances the efficacy of chemotherapy drugs against acute myeloid leukemia by inactivating the autophagy pathway 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 11 作者:  Wang, Han-lin;  Li, Jia-nan;  Kan, Wei-juan;  Xu, Gao-ya;  Luo, Guang-hao   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/10/17 acute myeloid leukemia  cytarabine  daunorubicin  idarubicin  drug resistant  multi-omics  autophagy  chloroquine phosphate   Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 14 作者:  Guo, Siqi;  Jia, Tongguan;  Xu, Xiaoming;  Yang, Feng;  Xiao, Senhao   |  收藏  |  浏览/下载：33/0  |  提交时间：2023/04/10 ENL Inhibitor  YEATS domain  Histone lysine acetylation  Benzimidazole derivatives  Acute myeloid leukemia   Design, synthesis, and evaluation of pyrido.[3,4-b]pyrazin-2(1H)-one derivatives as potent FLT3 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 79, 页码: 117155 作者:  Sun, Mei;  Wang, Chang;  Wang, Peipei;  Ye, Qingqing;  Zhou, Yubo   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/04/09 FLT3  FLT3-D835Y  Acute myeloid leukemia  Structure -activity relationships   Discover Novel Covalent Inhibitors Targeting FLT3 through Hybrid Virtual Screening Strategy 期刊论文  OAI收割 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2021, 卷号: 44, 期号: 12, 页码: 1872-1877 作者:  Hu, Shengquan;  Liu, Jing;  Chen, Sikang;  Gao, Jian;  Zhou, Yubo   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/06/15 acute myeloid leukemia  FMS-like tyrosine kinase 3  CovDock  hybrid virtual screening  autodock   Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13 作者:  Chen, Yun;  Bai, Gang;  Li, Yan;  Ning, Yi;  Cao, Sufen   |  收藏  |  浏览/下载：68/0  |  提交时间：2021/12/01 FLT3  FLT3-ITD  Acute myeloid leukemia  Structure-activity relationships  Pyrazolo[1, 5-a]pyrimidine   Traditional Chinese medicine compound, Bu Sheng Hui Yang Fang, promotes the proliferation of lymphocytes in the immunosuppressed mice potentially by upregulating IL-4 signaling 期刊论文  OAI收割 BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 134, 页码: 111107 作者:  Wang,Yajie;  Tan,Jiabin;  Hu,Peng;  Pei,Qiang;  Wen,Yan   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/04/02 Bu Shen Hui Yang Fang (BSHY)  Immunoenhancement  Lymphocytes  Proliferation  Cytokine  IL-4  ACUTE MYELOID-LEUKEMIA  IMMUNE-SYSTEM  CANCER  CELLS  IMMUNOSURVEILLANCE  EXPRESSION   Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7 作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan   |  收藏  |  浏览/下载：32/0  |  提交时间：2021/05/24 Drug design  CBP  Bromodomain  Inhibitor  Acute myeloid leukemia