中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [248]
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期刊论文 [1718]
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Design, synthesis and bio-evaluation of 2,5-disubstituted thiazole derivatives for potential treatment of acute myeloid leukemia through targeting CDK9
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 160, 页码: 16
作者:
Chen, Sumeng
;
Huang, Jindi
;
Zhang, Shipeng
;
Zheng, Xinni
;
Chen, Hongming
  |  
收藏
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浏览/下载:0/0
  |  
提交时间:2025/06/23
CDK9
Inhibitor
Acute myeloid leukemia
Binding mode
Cellular mechanism
SQSTM1/p62 Orchestrates Skin Aging via USP7 Degradation
期刊论文
OAI收割
AGING CELL, 2025, 页码: 16
作者:
Chen, Liu
;
Wang, Xiaoping
;
Wang, Yuchen
;
Yao, Qingxin
;
Liu, Yunyao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/23
binding interaction
skin aging
SQSTM1/p62
USP7
Targeting Two Odorant-Binding Proteins in Acyrthosiphon pisum: Discovery of Novel Jasmone Derivatives as Aphid Repellents
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2025, 卷号: 73, 期号: 19, 页码: 11998-12013
作者:
Zhu, Ziwei
;
Li, Huilin
;
Zhu, Wenya
;
Du, Shaoqing
;
Yang, Zhaokai
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
odorant-binding proteins
jasmone derivatives
rational design
aphid repellents
insect behaviorregulators
The effect of cations and metakaolin on chloride binding properties of mortars using simulated desalinated sea sand
期刊论文
OAI收割
ADVANCES IN CEMENT RESEARCH, 2025, 页码: 10
作者:
Sun, Congtao
;
Geng, Yuanjie
;
Zhang, Yuguo
;
Sun, Ming
;
Lu, Yihui
  |  
收藏
  |  
浏览/下载:0/0
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提交时间:2025/07/11
AFm phases
cations
chloride
chloride binding
C-S-H
metakaolin
simulated desalinated sea sand
Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
DeepFusion: A deep bimodal information fusion network for unraveling protein-RNA interactions using in vivo RNA structures
期刊论文
OAI收割
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2024, 卷号: 23, 页码: 617-625
作者:
Qiao, Yixuan
;
Yang, Rui
;
Liu, Yang
;
Chen, Jiaxin
;
Zhao, Lianhe
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/05/20
Information fusion
Deep learning
RNA -binding proteins
In vivo RNA structures
Motifs
Interaction-Based Inductive Bias in Graph Neural Networks: Enhancing Protein-Ligand Binding Affinity Predictions From 3D Structures
期刊论文
OAI收割
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2024, 卷号: 46, 期号: 12, 页码: 8191-8208
作者:
Yang, Ziduo
;
Zhong, Weihe
;
Lv, Qiujie
;
Dong, Tiejun
;
Chen, Guanxing
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/01/14
Proteins
Programmable logic arrays
Three-dimensional displays
Predictive models
Graph neural networks
Data models
Convolution
Protein-ligand binding affinity
graph neural networks
inductive bias
drug-target interaction
structure-based virtual screening
GPCR-BSD: a database of binding sites of human G-protein coupled receptors under diverse states
期刊论文
OAI收割
BMC BIOINFORMATICS, 2024, 卷号: 25, 期号: 1, 页码: 16
作者:
Liu, Fan
;
Zhou, Han
;
Li, Xiaonong
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/12/06
G-protein coupled receptor
State-specific structure
Binding site
Key residue
Database
Effect of chloride binding behavior of cement hydration products on chloride critical value of steel corrosion in the presence of Na+ and Ca2+
期刊论文
OAI收割
JOURNAL OF BUILDING ENGINEERING, 2024, 卷号: 94, 页码: 13
作者:
Sun, Ming
;
Sun, Congtao
;
Liu, Xiangju
;
Pan, Zihan
;
Duan, Jizhou
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/09/02
Chloride binding
Chloride critical value
Associated cation
C-S-H
AFm
IL-18 signaling is regulated by caspase 6/8 and IL-18BP in turbot (Scophthalmus maximus)
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 278, 页码: 13
作者:
Yu, Chao
;
Xu, Hang
;
Jiang, Shuai
;
Sun, Li
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/12/20
Teleost
Interleukin 18
Caspase
Interleukin 18 receptor
Interleukin 18 binding protein
Immune defense