中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
昆明植物研究所 [6]
金属研究所 [2]
过程工程研究所 [2]
海洋研究所 [2]
西双版纳热带植物园 [1]
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OAI收割 [20]
内容类型
期刊论文 [20]
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2025 [1]
2023 [1]
2022 [2]
2021 [2]
2019 [1]
2018 [2]
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学科主题
Pharmacolo... [3]
Chemistry [1]
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Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors
Bioassay-guided isolation of α-Glucosidase inhibitory constituents from Hypericum sampsonii
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 6, 页码: 443-453
作者:
Tao,Linlan
;
Xu,Shuangyu
;
Zhang,Zizhen
;
Li,Yanan
;
Yang,Jue
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/07/22
Hypericum sampsonii
Chemical constituents
Structure elucidation
alpha-Glucosidase
Molecular docking
POLYCYCLIC POLYPRENYLATED ACYLPHLOROGLUCINOLS
POTENT INHIBITORS
SPECTROSCOPY
DERIVATIVES
CHEMISTRY
AMYLASE
ROOTS
Discovery of CECR2 Bromodomain Inhibitors with High Selectivities over BPTF Bromodomain
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2022, 页码: 2072-2080
作者:
Lu, Haibo
;
Zu, Shijia
;
Duan, Zhe
;
Feng, Yueyao
;
Wang, Jie
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/08/16
CECR2 bromodomain
BPTF bromodomain
Inhibitors
Structure-activity relationships
chemical probe
Chemical constituents from the flowers of Hypericum monogynum L. with COX-2 inhibitory activity
期刊论文
OAI收割
PHYTOCHEMISTRY, 2022, 卷号: 193, 页码: 112970
作者:
Li,Ya-Nan
;
Zeng,Yan-Rong
;
Yang,Jue
;
He,Wenwen
;
Chen,Junlei
  |  
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2022/04/02
Hypericum monogynum L.
Hypericaceae
Chemical constituents
Polycyclic polyprenylated acylphloroglucinols
Flavonoids
COX-2 inhibitors
Chemical Synthesis of the Nucleoside Antibiotic Capuramycin
期刊论文
OAI收割
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 2021, 期号: 26, 页码: 3681-3689
作者:
Xiao,Guozhi
;
He,Haiqing
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/04/02
Capuramycin
Chemical synthesis
Glycosyl ortho-(1-phenylvinyl)benzoates
One-pot glycosylation
Tuberculosis
DRUG-RESISTANT TUBERCULOSIS
GLUTAMIC-ACID-DERIVATIVES
MULTIDRUG-RESISTANT
PROTECTING GROUPS
IN-VITRO
GLYCOSYLATION
INHIBITORS
ALCOHOLS
ANALOGS
OXIDATION
Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998
作者:
Huang,Qian
;
Chen,Ji-Jun
;
Pan,Yang
;
He,Xiao-Feng
;
Wang,Yuan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/04/02
Paeonia delavayi
Chemical comparison
LCMS analyses
Antidiabetic effects
PTP1B/TCPTP selective inhibitors
LIQUID-CHROMATOGRAPHY
MULTIPLE CONSTITUENTS
RAPID IDENTIFICATION
GLYCOSIDES
ROOT
DERIVATIVES
TARGETS
CAPSULE
L.
Effect of Novel Pretreatment of Steam Explosion Associated with Ammonium Sulfite Process on Enzymatic Hydrolysis of Corn Straw
期刊论文
OAI收割
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2019, 卷号: 189, 期号: 2, 页码: 485-497
作者:
Zhao, Qihong
;
Wang, Lan
;
Chen, Hongzhang
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2019/11/12
Steam explosion
Ammonium sulfite
Inhibitors removal
Enzymatic hydrolysis
Chemical humic acid
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 145-157
作者:
Li, Ning
;
Wang, Li-Jun
;
Jiang, Bo
;
Li, Xiang-qian
;
Guo, Chuan-long
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/08/21
DPP-4
Inhibitors
Analogs
Physico-chemical properties
SARs
Type 2 diabetes
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 145-157
作者:
Li, Ning
;
Wang, Li-Jun
;
Jiang, Bo
;
Li, Xiang-qian
;
Guo, Chuan-long
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2018/12/21
Dpp-4
Inhibitors
Analogs
Physico-chemical Properties
Sars
Type 2 Diabetes
Feeling Nature's PAINS: Natural Products, Natural Product Drugs, and Pan Assay Interference Compounds (PAINS)
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 3, 页码: 616-628
Baell, JB
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2017/01/12
POTASSIUM CHANNEL KV1.3
CLINICAL-TRIALS
CRYSTAL-STRUCTURE
TOXICOLOGICAL EVALUATION
CHEMICAL-PROPERTIES
REACTIVE COMPOUNDS
MOLECULAR-BASIS
VITAMIN-K
DISCOVERY
INHIBITORS