中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果:
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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:
Zhuo, Ning
;
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Yin, Jianpeng
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/25
Type 2 Diabetes
TGR5 agonist
Betulinic acid
Gut-restricted
Gallbladder-filling effects
Kinetophores
Association between triglyceride glucose index (TyG) and psychotic symptoms in patients with first-episode drug-na?ve major depressive disorder
期刊论文
OAI收割
FRONTIERS IN PSYCHIATRY, 2024, 卷号: 15, 页码: 11
作者:
Liu, Junjun
;
Wang, Yangchun
;
Mu, Wei
;
Liu, Yang
;
Tong, Ruixiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/04/15
major depressive disorder
psychotic symptoms
triglyceride glucose index
insulin resistance
type 2 diabetes mellitus
Exploration of the potential association between GLP-1 receptor agonists and suicidal or self-injurious behaviors: a pharmacovigilance study based on the FDA Adverse Event Reporting System database
期刊论文
OAI收割
BMC MEDICINE, 2024, 卷号: 22, 期号: 1, 页码: 13
作者:
Zhou, Jianxing
;
Zheng, You
;
Xu, Baohua
;
Long, Songjun
;
Zhu, Li-e
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/25
GLP-1RAs
Suicidal or self-injurious behaviors
Pharmacovigilance
FAERS database
Type 2 diabetes
Obesity
DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser
56
to diminish pancreatic β cell function upon overnutrition
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16
作者:
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收藏
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浏览/下载:16/0
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提交时间:2024/03/13
Autoimmune diseases: targets, biology, and drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Li, Shu-jie
;
Wu, Yan-li
;
Chen, Juan-hua
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
autoimmune disease
autoantigen
immunotherapy
type 1 diabetes
insulin
drug discovery
Paired box 6 gene delivery preserves beta cells and improves islet transplantation efficacy
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 20
作者:
So, Wing Yan
;
Liao, Yilie
;
Liu, Wai Nam
;
Rutter, Guy A.
;
Han, Weiping
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/11
AAV
beta cells
diabetes
islet transplant
PAX6
Therapeutic potential of enzymatically extracted eumelanin from squid ink in type 2 diabetes mellitus ICR mice: Multifaceted intervention against hyperglycemia, oxidative stress and depression
期刊论文
OAI收割
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2023, 页码: 15
作者:
Song, Wen
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/11/30
type 2 diabetes mellitus (T2DM)
eumelanin
hypoglycemic activity
antioxidant activity
antidepressant activity
An integrative profiling of metabolome and transcriptome in the plasma and skeletal muscle following an exercise intervention in diet-induced obese mice
期刊论文
OAI收割
JOURNAL OF MOLECULAR CELL BIOLOGY, 2023, 卷号: 15, 期号: 3, 页码: 14
作者:
Han, Shuang
;
Wu, Qingqian
;
Wang, Mengying
;
Yang, Miqi
;
Sun, Chen
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
type 2 diabetes
exercise intervention
metabolomics
transcriptomics
The development and benefits of metformin in various diseases
期刊论文
OAI收割
FRONTIERS OF MEDICINE, 2023, 页码: 44
作者:
Dong, Ying
;
Qi, Yingbei
;
Jiang, Haowen
;
Mi, Tian
;
Zhang, Yunkai
  |  
收藏
  |  
浏览/下载:19/0
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提交时间:2023/10/17
metformin
metabolism
cancer
aging
neurological disorder
Luteolin Protects Pancreatic beta Cells against Apoptosis through Regulation of Autophagy and ROS Clearance
期刊论文
OAI收割
PHARMACEUTICALS, 2023, 卷号: 16, 期号: 7, 页码: 17
作者:
Han, Ming
;
Lu, Yuting
;
Tao, Yunhua
;
Zhang, Xinwen
;
Dai, Chengqiu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
luteolin
type 2 diabetes
beta cell
autophagy
reactive oxygen species