机构

• 近代物理研究所 [3]
• 上海药物研究所 [2]
• 昆明植物研究所 [2]
• 成都生物研究所 [1]
• 水生生物研究所 [1]
• 海洋研究所 [1]
• 更多

采集方式

• OAI收割 [11]

内容类型

• 期刊论文 [11]

发表日期

• 2018 [1]
• 2016 [1]
• 2013 [1]
• 2012 [2]
• 2011 [1]
• 2010 [1]
• 更多

学科主题

• Biochemist... [1]
• Developmen... [1]
• Oncology; ... [1]

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文  OAI收割 CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621 作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang   |  收藏  |  浏览/下载：129/0  |  提交时间：2018/07/16 Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC   FS-108,an Hsp90 inhibitor,impairs survival and motility of oncogene addicted cancer cells 期刊论文  OAI收割 Chinese Pharmacological Bulletin, 2016, 卷号: 32, 期号: 10, 页码: 1357-1363 作者:  Ping Fangfang;  Wang Yueqin;  Zhang Minmin;  Shi Feng;  Chen Danqi   |  收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Hsp90  caspase-3  Hsp90  EBC-1 and A375 cells  G_2/M arrest  apoptosis  Caspase-3  migration   Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割 PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299 作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua 收藏  |  浏览/下载：47/0  |  提交时间：2015/05/14 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.   miR-3928 activates ATR pathway by targeting Dicer 期刊论文  OAI收割 RNA BIOLOGY, 2012, 卷号: 9, 页码: 1247-1254 作者:  Wu, Xin;  Yao, Bin;  Ye, Caiyong;  Hu, Wentao;  Chang, Lei   |  收藏  |  浏览/下载：20/0  |  提交时间：2018/07/04 Microrna  Dicer  Dna Damage  G1 Arrest  Ionizing Radiation   Monocytic Differentiation of K562 Cells Induced by Proanthocyanidins from Grape Seeds 期刊论文  OAI收割 ARCHIVES OF PHARMACAL RESEARCH, 2012, 卷号: 35, 页码: 129-135 作者:  Wang, Min;  Wang, Li;  Pan, Xiao-Jing;  Zhang, Hong   |  收藏  |  浏览/下载：23/0  |  提交时间：2018/07/05 Grape Seeds Procyanidins  Monocytic Differentiation  Intracellular Reactive Oxygen Species  K562 Cells  G1 Arrest   Cell cycle suspension A novel process lurking in G(2) arrest 期刊论文  OAI收割 CELL CYCLE, 2011, 卷号: 10, 页码: 1468-1476 作者:  Furusawa, Yoshiya;  Zhou, Guangming;  He, Jinpeng;  Li, Junhong;  Ye, Caiyong   |  收藏  |  浏览/下载：32/0  |  提交时间：2018/05/31 cell cycle  radiation  suspension  G(2) arrest  cyclin B1   Direct effects of fascaplysin on human umbilical vein endothelial cells attributing the anti-angiogenesis activity 期刊论文  OAI收割 BIOMEDICINE & PHARMACOTHERAPY, 2010, 卷号: 64, 期号: 8, 页码: 527-533 作者:  Zheng, Y. L.;  Lu, X. L.;  Lin, J.;  Chen, H. M.;  Yan, X. J. 收藏  |  浏览/下载：37/0  |  提交时间：2015/07/20 Fascaplysin  Anti-angiogenesis  HUVEC  G1 cell cycle arrest  Apoptosis   C1q-like inhibits p53-mediated apoptosis and controls normal hernatopoiesis during zebrafish embryogenesis 期刊论文  OAI收割 DEVELOPMENTAL BIOLOGY, 2008, 卷号: 319, 期号: 2, 页码: 273-284 作者:  Mei, Jie;  Zhang, Qi-Ya;  Li, Zhi;  Lin, Shuo;  Gui, Jian-Fang 收藏  |  浏览/下载：90/3  |  提交时间：2010/10/13 C1q-like factor  p53  caspase 3/9  brain  zebrafish  apoptosis  G2/M phase arrest  hematopoiesis   Induction of G1 arrest and differentiation in MDA-MB-231 breast cancer cell by boehmeriasin A, a novel compound from plant 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2006, 卷号: 16, 期号: 1, 页码: 165_170 Yan, J; Luo, D; Luo, Y; Gao, X; Zhang, G 收藏  |  浏览/下载：22/0  |  提交时间：2011/07/08 boehmeriasin A  breast cancer cell  differentiation  G1 arrest   The Emergent Role of p38 MAPKs in the Regulation of Cell Cycle 期刊论文  OAI收割 Progress in Physiological Sciences, 2004, 卷号: 35, 期号: 4, 页码: 315-320 作者:  Chen Yi;  Miao Zehong;  Ding Jian   |  收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 p38 MAPKs  p38 MAPKs  Cell cycle arrest  G1/S checkpoint  G2/M checkpoint