机构

• 上海药物研究所 [46]
• 西北高原生物研究所 [2]
• 水生生物研究所 [2]
• 合肥物质科学研究院 [2]
• 昆明动物研究所 [2]
• 大连化学物理研究所 [1]
• 更多

采集方式

• OAI收割 [56]

内容类型

• 期刊论文 [53]
• 会议论文 [3]

发表日期

• 2024 [2]
• 2022 [3]
• 2021 [6]
• 2020 [2]
• 2018 [5]
• 2017 [4]
• 更多

学科主题

• Biochemist... [1]
• Biophysics [1]
• Cell Biolo... [1]
• 生物科学 [1]

筛选

浏览/检索结果: 共56条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12 作者:  He, Xin-heng;  Li, Jun-rui;  Shen, Shi-yi;  Xu, H. Eric   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/01/14 AlphaFold  structure-based drug design  artificial intelligence  GPCR  structural biology   Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 41, 页码: 11 作者:  Wang, Yujue;  Xu, Youwei;  Wang, Yue;  Zhang, Jie;  Chen, Lan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/12/11 GPCR  somatostatin receptors  ligand selectivity  neuroendocrine tumor  |cryo-EM   Recent progress in assays for GPCR drug discovery 期刊论文  OAI收割 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022, 卷号: 323, 期号: 2, 页码: C583-C594 作者:  Guo, Shimeng;  Zhao, Tingting;  Yun, Ying;  Xie, Xin   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/04/10 biased signaling  GPCR  high -throughput screening assays  humanized mouse model  protein  protein interaction   Solubilization, purification, and ligand binding characterization of G protein-coupled receptor SMO in native membrane bilayer using styrene maleic acid copolymer 期刊论文  OAI收割 PEERJ, 2022, 卷号: 10 作者:  Zhu, Lina;  Zhao, Hongxin;  Wang, Yizhuo;  Yu, Chuandi;  Liu, Juanjuan   |  收藏  |  浏览/下载：41/0  |  提交时间：2022/12/23 GPCR  Dissociation constant  Detergents  Styrene maleic acid copolymer nanodiscs  Smoothened receptors  NMR   Modulating effects of RAMPs on signaling profiles of the glucagon receptor family 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 2, 页码: 637-650 作者:  Shao, Lijun;  Chen, Yan;  Zhang, Shikai;  Zhang, Zhihui;  Cao, Yongbing   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/06/15 G protein-coupled receptor  Glucagon receptor family  Receptor activity-modulating protein  Signaling  Allosteric modulation  GPCR-RAMP interaction  Receptor pharmacology  Ligand selectivity   GLP-1 mimetics as a potential therapy for nonalcoholic steatohepatitis 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Chen, Yan;  Xu, Ying-na;  Ye, Chen-yu;  Feng, Wen-bo;  Zhou, Qing-tong   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/06/15 NAFLD  NASH  GLP-1R  GLP-1 mimetics  dual agonists  triple agonists  GPCR   GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Zhang, Qing;  Chen, Lin-hai;  Yang, Hui;  Fang, You-chen;  Wang, Si-wei   |  收藏  |  浏览/下载：66/0  |  提交时间：2022/01/18 GPR84  medium chain fatty acid receptor  GPCR  inflammatory bowel diseases  ulcerative colitis  NLRP3 inflammasome  macrophages   Constitutive signal bias mediated by the human GHRHR splice variant 1 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10 作者:  Cong, Zhaotong;  Zhou, Fulai;  Zhang, Chao;  Zou, Xinyu;  Zhang, Huibing   |  收藏  |  浏览/下载：71/0  |  提交时间：2021/12/01 class B1 GPCR  receptor bias  cancer  cell proliferation   Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16 作者:  Yuliantie, Elita;  van der Velden, Wijnand J. C.;  Labroska, Viktorija;  Dai, Antao;  Zhao, Fenghui   |  收藏  |  浏览/下载：100/0  |  提交时间：2021/11/04 Glucose-dependent insulinotropic polypeptide receptor  G protein-coupled receptor  GPCR structure-function relationship  ERK  cAMP  Arrestin   Different conformational responses of the beta(2)-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline 期刊论文  OAI收割 NATIONAL SCIENCE REVIEW, 2021, 卷号: 8 作者:  Yang, Fan;  Ling, Shenglong;  Zhou, Yingxin;  Zhang, Yanan;  Lv, Pei   |  收藏  |  浏览/下载：42/0  |  提交时间：2021/11/01 cryo-EM structure  G protein-coupled receptor (GPCR)  partial and full agonists  conformational change  desensitization