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中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [32]
海洋研究所 [8]
昆明植物研究所 [4]
上海应用物理研究所 [3]
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期刊论文 [48]
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学位论文 [2]
CNKI期刊论文 [1]
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Identification and biological evaluation of fused tetrahydroisoquinoline derivatives as Wnt/β-catenin signaling inhibitors to suppress colorectal cancer
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 276, 页码: 16
作者:
Zhou, Jianhui
;
Xu, Beibei
;
Shen, Qianwen
;
Zhang, Zhenwei
;
Hu, Yuting
|
收藏
|
浏览/下载:19/0
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提交时间:2024/09/26
Key & Oslash
Colorectal cancer
Wnt/ beta-catenin
Hsp90
Tetrahydroisoquinoline
rds
Development of HSP90 inhibitors-SN38 conjugates for cancer treatment
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 137, 页码: 11
作者:
Cao, Yuting
;
Shen, Qianqian
;
Ding, Mengyuan
;
Chen, Yi
;
Lu, Wei
|
收藏
|
浏览/下载:78/0
|
提交时间:2023/10/17
HSP90
SN38 conjugate
Drug accumulation
Cancer treatment
Dipyridamole interacts with the N-terminal domain of HSP90 and antagonizes the function of the chaperone in multiple cancer cell lines
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 207, 页码: 16
作者:
Gao, Jing
;
Zhou, Chen
;
Zhong, Yan
;
Shi, Li
;
Luo, Xuanyang
|
收藏
|
浏览/下载:33/0
|
提交时间:2023/04/10
HSP90
ATP competitive inhibitors
Tip-based affinity selection-mass spectrometry
Dipyridamole
Cell cycle regulators
7-aminocephalosporanic acid, a novel HSP90 beta inhibitor, attenuates HFD-induced hepatic steatosis
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, 卷号: 622, 页码: 184-191
作者:
Zhang, Weitao
;
Xue, Hanyue
;
Zhou, Chen
;
Zheng, Zuguo
;
Xing, Mingming
|
收藏
|
浏览/下载:51/0
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提交时间:2022/12/13
7-aminocephalosporanic acid
HSP90 beta
NAFLD
de novo lipogenesis
SPR
HSP90 N-terminal inhibitors target oncoprotein MORC2 for autophagic degradation and suppress MORC2-driven breast cancer progression
期刊论文
OAI收割
CLINICAL AND TRANSLATIONAL MEDICINE, 2022, 卷号: 12, 期号: 5, 页码: 18
作者:
Yang, Fan
;
Sun, Rui
;
Hou, Zeng
;
Zhang, Fang-Lin
;
Xiao, Yi
|
收藏
|
浏览/下载:65/0
|
提交时间:2022/06/15
breast cancer
chaperone-mediated autophagy
HSP90 inhibitor
MORC2
protein degradation
Expression Patterns of the Heat Shock Protein 90 (Hsp90) Gene Suggest Its Possible Involvement in Maintaining the Dormancy of Dinoflagellate Resting Cysts
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 20, 页码: 18
作者:
Deng, Yunyan
;
Li, Fengting
;
Hu, Zhangxi
;
Yue, Caixia
;
Tang, Ying Zhong
|
收藏
|
浏览/下载:37/0
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提交时间:2022/01/05
dinoflagellate
dormancy
environmental cDNA library
heat shock protein 90 (Hsp90)
resting cysts
Scrippsiella trochoidea
temperature stress
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:
Liu,Jiangxin
;
Wu,Xing-De
;
Li,Wenyan
;
Yuan,Zaifeng
;
Yang,Kun
|
收藏
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浏览/下载:26/0
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提交时间:2022/04/02
Pseudolaric acid A
Hsp90 inhibitor
Apoptosis
NMR
Structure-activity relationship
Photoaffinity-based probe
Protein-ligand interaction
MOLECULAR CHAPERONE
PROTEIN
TARGET
CANCER
KINASE
NMR
IDENTIFICATION
SELECTIVITY
BINDING
DESIGN
Heat shock protein 101 (HSP101) promotes flowering under nonstress conditions
期刊论文
OAI收割
PLANT PHYSIOLOGY, 2021, 卷号: 186, 期号: 1, 页码: 407-419
作者:
Qin,Feng
;
Yu,Buzhu
;
Li,Weiqi
|
收藏
|
浏览/下载:61/0
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提交时间:2022/04/02
MOLECULAR CHAPERONES
ARABIDOPSIS
EXPRESSION
TIME
HSP90
TRANSCRIPTION
TOLERANCE
REPRESSOR
THERMOTOLERANCE
OVEREXPRESSION
DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Chen, Xiang-ling
;
Liu, Peng
;
Zhu, Wei-liang
;
Lou, Li-guang
|
收藏
|
浏览/下载:36/0
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提交时间:2020/07/01
DCZ5248
Hsp90
autophagy
lysosomal function
antitumor activity
colon cancer
Ansamycin derivatives from the marine-derived Streptomyces sp. SCSGAA 0027 and their cytotoxic and antiviral activities
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 127168
作者:
Nong, Xu-Hua
;
Tu, Zheng-Chao
;
Qi, Shu-Hua
|
收藏
|
浏览/下载:49/0
|
提交时间:2020/09/22
Streptomyces sp.
Ansamycin
Herbimycin
Divergolide
Cytotoxicity
anti-HSV-1 activity
Hsp90 inhibition
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