机构

• 上海药物研究所 [8]
• 昆明植物研究所 [2]

采集方式

• OAI收割 [10]

内容类型

• 期刊论文 [10]

发表日期

• 2022 [1]
• 2021 [1]
• 2019 [1]
• 2018 [2]
• 2017 [1]
• 2015 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共10条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 HSP90 N-terminal inhibitors target oncoprotein MORC2 for autophagic degradation and suppress MORC2-driven breast cancer progression 期刊论文  OAI收割 CLINICAL AND TRANSLATIONAL MEDICINE, 2022, 卷号: 12, 期号: 5, 页码: 18 作者:  Yang, Fan;  Sun, Rui;  Hou, Zeng;  Zhang, Fang-Lin;  Xiao, Yi   |  收藏  |  浏览/下载：61/0  |  提交时间：2022/06/15 breast cancer  chaperone-mediated autophagy  HSP90 inhibitor  MORC2  protein degradation   Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963 作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/04/02 Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN   Design, Synthesis and Pharmacological Evaluation of Novel Hsp90N-terminal Inhibitors Without Induction of Heat Shock Response 期刊论文  OAI收割 CHEMISTRYOPEN, 2019, 卷号: 8, 期号: 3, 页码: 344-353 作者:  Liu, Peng;  Chen, Xiangling;  Zhu, Jianming;  Li, Bo;  Chen, Zhaoqiang   |  收藏  |  浏览/下载：53/0  |  提交时间：2020/07/01 autophagy  Hsp72  Hsp90 inhibitor  triazines  antitumor activity   Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86 作者:  Geng, Kaijun;  Liu, Hongchun;  Song, Zilan;  Zhang, Chi;  Zhang, Minmin   |  收藏  |  浏览/下载：190/0  |  提交时间：2019/01/08 Heat shock protein 90 (Hsp90)  Tyrosine kinase ALK  Dual inhibitor  Drug resistance  Antiproliferative activity   Vibsane-Type Diterpenoids from Viburnum odoratissimum and Their Cytotoxic and HSP90 Inhibitory Activities 期刊论文  OAI收割 CHEMISTRY & BIODIVERSITY, 2018, 卷号: 15, 期号: 5, 页码: 1800049 作者:  Zhu, Qin-Feng;  Qi, Yan-Yan;  Zhang, Zhi-Jun;  Fan, Min;  Bi, Ran   |  收藏  |  浏览/下载：44/0  |  提交时间：2018/07/16 Vibsane-type Diterpenoids  Viburnum Odoratissimum  Cytotoxicity  Hsp90 Inhibitor   Design, synthesis and pharmacological evaluation of 4,5-diarylisoxazols bearing amino acid residues within the 3-amido motif as potent heat shock protein 90 (Hsp90) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 125, 页码: 315-326 作者:  Zhang, Chi;  Wang, Xin;  Liu, Hongchun;  Zhang, Minmin;  Geng, Meiyu   |  收藏  |  浏览/下载：55/0  |  提交时间：2019/01/08 Diarylisoxazole  Resorcinol  Amino acid  Hsp90 inhibitor  Antiproliferative effect   Identification of epipolythiodioxopiperazines HDN-1 and chaetocin as novel inhibitor of heat shock protein 90 期刊论文  OAI收割 ONCOTARGET, 2015, 卷号: 6, 期号: 7, 页码: 5263-5274 作者:  Song, Xiaoping;  Zhao, Zhimin;  Qi, Xin;  Tang, Shuai;  Wang, Qiang   |  收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 pipolythiodioxopiperazines  HDN-1  chaetocin  inhibitor  Hsp90   Progress in the study of small molecule inhibitors of HSP90 期刊论文  OAI收割 Acta Pharmaceutica Sinica, 2015, 卷号: 50, 期号: 6, 页码: 640-649 作者:  Ren Jing;  Yan Bibo;  Shi Feng;  Xiong Bing;  Shen Jingkang   |  收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 HSP90  HSP90  client protein  tumor  inhibitor   HSP90 inhibitor AUY922 abrogates up-regulation of RTKs by mTOR inhibitor AZD8055 and potentiates its antiproliferative activity in human breast cancer 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF CANCER, 2014, 卷号: 135, 期号: 10, 页码: 2462-2474 作者:  Chen, Si-Meng;  Guo, Chen-Liang;  Shi, Jia-Jie;  Xu, Yi-Chao;  Chen, Yi   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 mTOR kinase inhibitor  HSP90 inhibitor  breast cancer  receptor tyrosine kinases  drug combination   Inhibition of hepatic stellate cell proliferation by heat shock protein 90 inhibitors in vitro 期刊论文  OAI收割 MOLECULAR AND CELLULAR BIOCHEMISTRY, 2009, 卷号: 330, 期号: 1-2, 页码: 181-185 作者:  Sun, Xu;  Zhang, Xiao-Dong;  Cheng, Gang;  Hu, You-Hong;  Wang, He-Yao   |  收藏  |  浏览/下载：70/0  |  提交时间：2019/01/08 Hepatic stellate cells  Hsp90 inhibitor  Proliferation  Cell cycle