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Terpenoids from Nardostachys jatamansi and Their Cytotoxic Activity against Human Pancreatic Cancer Cell Lines 期刊论文  OAI收割
Phytochemistry, 2022, 期号: 200, 页码: 113228
作者:  
Li-Mei Ma;  Kai Wang;  Xian-Hua Meng;  Yi-Dan Zheng;  Cheng-Bo Wang
  |  收藏  |  浏览/下载:41/0  |  提交时间:2022/11/30
Interrogating the variation of element masses and distribution patterns in single cells using ICP-MS with a high efficiency cell introduction system 期刊论文  OAI收割
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2017, 卷号: 409, 期号: 5, 页码: 1415-1423
作者:  
Wang, M;  Wang HL(王海龙);  Wang M(王萌);  Wang B(汪冰);  Zheng LN(郑令娜)
  |  收藏  |  浏览/下载:27/0  |  提交时间:2019/08/27
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  
Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
收藏  |  浏览/下载:47/0  |  提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.  
Stem cell properties and neural differentiation of sheep amniotic epithelial cells 期刊论文  OAI收割
NEURAL REGENERATION RESEARCH, 2013, 卷号: 8, 期号: 13, 页码: 1210-1219
作者:  
Zhu Xuemin;  Wang Xiumei;  Cao Guifang;  Liu Fengjun;  Yang Yinfeng
  |  收藏  |  浏览/下载:33/0  |  提交时间:2021/02/02
Stem cell properties and neural differentiation of sheep amniotic epithelial cells 期刊论文  OAI收割
NEURAL REGENERATION RESEARCH, 2013, 卷号: 8, 期号: 13, 页码: 1210-1219
作者:  
Zhu Xuemin;  Wang Xiumei;  Cao Guifang;  Liu Fengjun;  Yang Yinfeng
  |  收藏  |  浏览/下载:26/0  |  提交时间:2021/02/02
Chemical Constituents from the Aerial Parts of Isodon coetsa and their Cytotoxicity 期刊论文  OAI收割
ARCHIVES OF PHARMACAL RESEARCH, 2011, 卷号: 34, 期号: 12, 页码: 2007-2014
作者:  
Zhao, Wei;  Pu, Jian Xin;  Du, Xue;  Wu, Ying Li;  Zhao, Yong
收藏  |  浏览/下载:32/0  |  提交时间:2012/04/10
Radiosensitivity of hepatoma cell lines and human normal liver cell lines exposed in vitro to carbon ions and argon ions at the HIRFL 期刊论文  OAI收割
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, 2009, 卷号: 267, 期号: 10, 页码: 1837-1840
作者:  
Jing, Xigang;  Li, Wenjian;  Wang, Zhuanzi;  Wei, Wei;  Guo, Chuanling
  |  收藏  |  浏览/下载:31/0  |  提交时间:2010/10/29
Effect of 80.55 MeV/u(12)C(6+) ions on radiosensitivity and cell cycle of human hepatoma cell lines 期刊论文  OAI收割
PLASMA SCIENCE & TECHNOLOGY, 2008, 卷号: 10, 期号: 2, 页码: 245-249
作者:  
WEI Wei;  LI Wenjian;  GUO Chuanling;  JING Xigang;  JIN Xiaodong
  |  收藏  |  浏览/下载:32/0  |  提交时间:2010/10/29
Ethyl acetate extracted from Shiitake Mushroom induced apoptosis in a breast cancer cell line-MCF-7 期刊论文  OAI收割
Chinese Pharmacological Bulletin, 2006, 卷号: 22, 期号: 8, 页码: 1001-1004
作者:  
LI Qinglin;  LUO Hongfeng;  FANG Nianbai
  |  收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Effects of Huangqi (Hex) on inducing cell differentiation and cell death in K562 and HEL cells 期刊论文  OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2004, 卷号: 36, 期号: 3, 页码: 211-217
作者:  
Cheng, XD;  Hou, CH;  Zhang, XJ;  Xie, HY;  Zhou, WY
收藏  |  浏览/下载:27/0  |  提交时间:2015/07/22