机构

• 上海神经科学研究所 [10]
• 上海药物研究所 [10]
• 合肥物质科学研究院 [2]
• 生物物理研究所 [1]
• 金属研究所 [1]
• 上海生物化学与细胞生... [1]
• 更多

采集方式

• OAI收割 [27]

内容类型

• 期刊论文 [27]

发表日期

• 2024 [1]
• 2018 [3]
• 2015 [2]
• 2014 [1]
• 2013 [4]
• 2012 [2]
• 更多

学科主题

• Cell Biolo... [5]
• Pharmacolo... [5]
• Neuroscien... [4]
• Oncology [4]
• Biochemist... [2]
• Chemistry [1]
• 更多

筛选

浏览/检索结果: 共27条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Structure-based development of potent and selective type-II kinase inhibitors of RIPK1 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334 作者:  Qin, Ying;  Li, Dekang;  Qi, Chunting;  Xiang, Huaijiang;  Meng, Huyan   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/03/06 RIPK1  Necroptosis  Type-II kinase inhibitors  Rational design  Lead optimization  Structure-activity relationship  Anti-inflammation  Preclinical drug discovery   Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFR alpha kinase inhibitor for PDGFR alpha driving chronic eosinophilic leukemia 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 150, 期号: 无, 页码: 366-384 作者:  Wang, Qiang;  Liu, Feiyang;  Qi, Shuang;  Qi, Ziping;  Yan, Xiao-E.   |  收藏  |  浏览/下载：75/0  |  提交时间：2019/06/10 PDGFR kinase  Type II inhibitor  Kinase inhibitor  CEL   Targeting HER2 Aberrations in Non-Small Cell Lung Cancer with Osimertinib 期刊论文  OAI收割 CLINICAL CANCER RESEARCH, 2018, 卷号: 24, 期号: 11, 页码: 2594-2604 作者:  Liu, Shengwu;  Hai, Josephine;  Wang, Xiaoen;  Quinn, Max M.   |  收藏  |  浏览/下载：94/0  |  提交时间：2019/04/28 Receptor Tyrosine Kinase  Phase-ii Trial  Bromodomain Inhibition  Combination Therapy  Acquired-resistance  Domain Mutations  Bet Bromodomains  Breast-cancer  Egfr  Mutant   SGK1-FoxO1 Signaling Pathway Mediates Th17/Treg Imbalance and Target Organ Inflammation in Angiotensin II-Induced Hypertension 期刊论文  OAI收割 FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9, 期号: -, 页码: 1581 作者:  Du, Ya-Nan;  Tang, Xiao-Feng;  Xu, Lian;  Chen, Wen-Dong;  Gao, Ping-Jin   |  收藏  |  浏览/下载：17/0  |  提交时间：2020/12/09 serum/glucocorticoid regulated kinase 1  Th17 cells  Treg cells  target organ damage  angiotensin II   Spatiotemporal dynamics of traction forces show three contraction centers in migratory neurons 期刊论文  OAI收割 JOURNAL OF CELL BIOLOGY, 2015, 卷号: 209, 期号: 5, 页码: 759-774 作者:  Jiang, J;  Zhang, ZH;  Yuan, XB;  Poo, MM 收藏  |  浏览/下载：45/0  |  提交时间：2015/12/30 FOCAL ADHESION KINASE  COLLECTIVE CELL-MIGRATION  MYOSIN-II  MEMBRANE TENSION  INTEGRIN ACTIVATION  NEUROTROPHIC FACTOR  ACTIN DYNAMICS  AXON GUIDANCE  GROWTH CONE  MICROTUBULES   Identification and characterization of chloroplast casein kinase II from Oryza sativa (rice) 期刊论文  OAI收割 JOURNAL OF EXPERIMENTAL BOTANY, 2015, 卷号: 66, 期号: 1, 页码: 175-187 作者:  Lu, Qingtao;  Ding, Shunhua;  Reiland, Sonja;  Roediger, Anja;  Roschitzki, Bernd   |  收藏  |  浏览/下载：42/0  |  提交时间：2022/09/13 Casein kinase II  chloroplast  mass spectrometry  phosphorylation  substrates  transcriptionally active chromosome   CaMKII alpha and caveolin-1 cooperate to drive ATP-induced membrane delivery of the P2X3 receptor 期刊论文  OAI收割 JOURNAL OF MOLECULAR CELL BIOLOGY, 2014, 卷号: 6, 期号: 2, 页码: 140-153 Chen, XQ; Zhu, JX; Wang, Y; Zhang, X; Bao, L 收藏  |  浏览/下载：41/0  |  提交时间：2014/07/30 PROTEIN-KINASE-II  ROOT GANGLION NEURONS  PRIMARY SENSORY NEURONS  GENE-RELATED PEPTIDE  D-ASPARTATE RECEPTOR  P2X(3) RECEPTOR  DIFFERENTIAL EXPRESSION  NR2B SUBUNIT  RAT  PHOSPHORYLATION   Naphthalimides exhibit in vitro antiproliferative and antiangiogenic activities by inhibiting both topoisomerase II (topo II) and receptor tyrosine kinases (RTKs) 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 65, 页码: 477-486 作者:  Wang, Xin;  Chen, Zhuo;  Tong, Linjiang;  Tan, Shaoying;  Zhou, Wei   |  收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 Angiogenesis  Multitarget  Naphthalimide  Topoisomerase II  Tyrosine kinase   Astragaloside II triggers T cell activation through regulation of CD45 protein tyrosine phosphatase activity 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 4, 页码: 522-530 作者:  Wan, Chun-ping;  Gao, Li-xin;  Hou, Li-fei;  Yang, Xiao-qian;  He, Pei-lan   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 immunomodulating agent  Astragalus membranaceus Bge  astragaloside II  CD45 PTPase  LCK  T cell  splenocyte  Src-family kinase  IFN-gamma  IL-2  cyclophosphamide   astragalosidetriggerstcellactivationthroughregulationofcd45proteintyrosinephosphataseactivity 期刊论文  OAI收割 actapharmacologicasinica, 2013, 卷号: 34, 期号: 4, 页码: 522 作者:  Wan Chunping;  Gao Lixin;  Hou Lifei;  Yang Xiaoqian;  He Peilan   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 immunomodulating agent  Astragalus membranaceus Bge  astragaloside II  CD45 PTPase  LCK  T cell  splenocyte  Src-family kinase  IFN-y  IL-2  cyclophosphamide