机构

• 上海药物研究所 [25]
• 长春应用化学研究所 [17]
• 力学研究所 [15]
• 生态环境研究中心 [7]
• 福建物质结构研究所 [6]
• 中国科学院大学 [6]
• 更多

采集方式

• OAI收割 [100]
• iSwitch采集 [7]

内容类型

• 期刊论文 [101]
• 学位论文 [3]
• 会议论文 [2]
• CNKI期刊论文 [1]

发表日期

• 2024 [2]
• 2023 [4]
• 2022 [3]
• 2021 [3]
• 2020 [2]
• 2019 [3]
• 更多

学科主题

• Biochemist... [7]
• Chemistry [3]
• Biochemist... [2]
• Biotechnol... [2]
• Pharmacolo... [2]
• Biophysics [1]
• 更多

筛选

浏览/检索结果: 共107条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Interaction-Based Inductive Bias in Graph Neural Networks: Enhancing Protein-Ligand Binding Affinity Predictions From 3D Structures 期刊论文  OAI收割 IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2024, 卷号: 46, 期号: 12, 页码: 8191-8208 作者:  Yang, Ziduo;  Zhong, Weihe;  Lv, Qiujie;  Dong, Tiejun;  Chen, Guanxing   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/01/14 Proteins  Programmable logic arrays  Three-dimensional displays  Predictive models  Graph neural networks  Data models  Convolution  Protein-ligand binding affinity  graph neural networks  inductive bias  drug-target interaction  structure-based virtual screening   Development and Validation of an ADA-Tolerant Assay for Quantification of an Exatecan-Based ADC in Monkey Plasma 期刊论文  OAI收割 MOLECULES, 2024, 卷号: 29, 期号: 3, 页码: 14 作者:  Tao, Yimin;  Lu, Wei;  Gao, Jinli;  Yang, Shuangshuang;  Ruan, Chaoyi   |  收藏  |  浏览/下载：38/0  |  提交时间：2024/03/13 antibody-drug conjugate (ADC)  bioanalysis  anti-drug antibody (ADA)  ligand binding assay (LBA)  ADA-tolerant assay   Structural insights into the interaction of three Y- shaped ligands with PI3Kα 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 34, 页码: 9 作者:  Zhou, Qingtong;  Liu, Xiao;  Neri, Dario;  Li, Wenxin;  Favalli, Nicholas   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/12/08 phosphoinositide 3-kinase  drug target  ligand  binding pocket  chemical scaffold   Receptor-Ligand Binding: Effect of Mechanical Factors 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 9062 作者:  Du, Ruotian;  Li L(李龙);  Ji, Jing;  Fan, Yubo;  Li L(李龙)   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/06/15 receptor-ligand binding  tension  shear stress  stretch  compression  substrate stiffness  biomechanics  mechanotransduction   Two dimensional measurements of receptor ligand interactions 期刊论文  OAI收割 FRONTIERS IN MOLECULAR BIOSCIENCES, 2023, 卷号: 10, 页码: 1154074 作者:  Zheng SJ(郑松杰);  Zou M(邹敏);  Shao YF(邵颖峰);  Wu, Huaping;  Wu, Helong   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/04/20 receptor ligand interaction  binding kinetics  kinetic on rate  kinetic off rate  binding affinity  two dimensional measuring methods   Intercellular Receptor-ligand Binding: Effect of Protein-membrane Interaction 期刊论文  OAI收割 JOURNAL OF MOLECULAR BIOLOGY, 2023, 卷号: 435, 期号: 1, 页码: 17 作者:  Li, Long;  Ji, Jing;  Song, Fan;  Hu, Jinglei;  Song F(宋凡)   |  收藏  |  浏览/下载：56/0  |  提交时间：2023/03/08 Protein-membrane interaction  Intercellular receptor-ligand binding  Membrane fluctuations and curvature  Glycocalyx  Lipid raft   2,2 ',4,4 '-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPAR gamma Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation 期刊论文  OAI收割 CHEMICAL RESEARCH IN TOXICOLOGY, 2022, 卷号: 35, 期号: 6, 页码: 1023-1035 作者:  Ren, Qidong;  Xie, Xinni;  Zhao, Chuanfang;  Wen, Qing;  Pan, Ruiying   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/11/08 ACTIVATED-RECEPTOR-GAMMA  BROMINATED FLAME RETARDANTS  ACID-BINDING PROTEIN  GENE-EXPRESSION  LIGAND-BINDING  DIPHENYL ETHERS  INDOOR DUST  EXPOSURE  CD36  ACCUMULATION   Insights into intercellular receptor-ligand binding kinetics in cell communication 期刊论文  OAI收割 FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 卷号: 10, 页码: 953353 作者:  An, Chenyi;  Wang, Xiaohuan;  Song F(宋凡);  Hu, Jinglei;  Li L(李龙)   |  收藏  |  浏览/下载：42/0  |  提交时间：2022/10/23 cell communication  intercellular receptor-ligand binding kinetics  protein-membrane interaction  biomechanical force  bioelectric microenvironment   Development and validation of a ligand-binding assay for quantification of the F(ab')(2) antivenom of Daboia russelii siamensis in human serum and its application to a phase I clinical study 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2022, 卷号: 212, 页码: 8 作者:  Gui, Yuzhou;  Yu, Chengyin;  Zhou, Jiaye;  Xin, Liang;  Chen, Ze   |  收藏  |  浏览/下载：57/0  |  提交时间：2022/06/15 F(ab')(2) antivenom  Daboia russelii siamensis  Ligand-binding assay  Method validation  Clinical trial   CSConv2d: A 2-D Structural Convolution Neural Network with a Channel and Spatial Attention Mechanism for Protein-Ligand Binding Affinity Prediction 期刊论文  OAI收割 BIOMOLECULES, 2021, 卷号: 11, 期号: 5, 页码: 9 作者:  Wang, Xun;  Liu, Dayan;  Zhu, Jinfu;  Rodriguez-Paton, Alfonso;  Song, Tao   |  收藏  |  浏览/下载：62/0  |  提交时间：2021/12/01 protein-ligand binding affinity  2-D structural CNN  spatial attention mechanism