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浏览/检索结果: 共627条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with Gs proteins 期刊论文  OAI收割 CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 13 作者:  Cong, Zhaotong;  Zhao, Fenghui;  Li, Yang;  Luo, Gan;  Mai, Yiting   |  收藏  |  浏览/下载：21/0  |  提交时间：2024/03/13 Nanobodies as negative allosteric modulators for human calcium sensing receptor 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9 作者:  Cui, Qianqian;  Wang, Lu;  Wang, Haonan;  Chen, Xiaochen;  Han, Li   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/04/09 G-protein-coupled receptor  Extracellular calcium sensing receptor  Nanobody  Cryo-electron microscope  Systemic Ca 2+homoeostasis   Recognition of methamphetamine and other amines by trace amine receptor TAAR1 期刊论文  OAI收割 NATURE, 2023, 卷号: 624, 期号: 7992, 页码: 663-+ 作者:  Liu, Heng;  Zheng, You;  Wang, Yue;  Wang, Yumeng;  He, Xinheng   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/03/25 Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study 期刊论文  OAI收割 JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12 作者:  Zhao, Tian-Tian;  Hu, Hao-Jie;  Gao, Li-Xin;  Zhou, Yu-Bo;  Zhu, Yun-Long   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Protein tyrosine phosphatases inhibitors  PTP1B inhibitors  Mechanism study  Molecular dynamics   Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2 期刊论文  OAI收割 CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 19 作者:  Zhu, Shengnan;  Yuan, Qingning;  Li, Xinzhu;  He, Xinheng;  Shen, Shiyi   |  收藏  |  浏览/下载：99/0  |  提交时间：2024/01/16 different ligands  recognition  ligand selectivity  receptor   The new direction of drug development: Degradation of undruggable targets through targeting chimera technology 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54 作者:  Liang, Xuewu;  Ren, Hairu;  Han, Fengyang;  Liang, Renwen;  Zhao, Jiayan   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/01/16 chimeric design  degradation System  PROTAC  targeted degradation technology  undruggable targets   Membrane-Mediated Cooperative Interactions of CD47 and SIRPα 期刊论文  OAI收割 MEMBRANES, 2023, 卷号: 13, 期号: 11, 页码: 13 作者:  Li L(李龙);  Gui, Chen;  Hu, Jinglei;  Rozycki, Bartosz   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/01/02 membrane adhesion  biomimetics  computer simulations  CD47  SIRP alpha   Discovery of Potent and Selective CB2 Agonists Utilizing a Function-Based Computational Screening Protocol 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2023, 卷号: 14, 期号: 21, 页码: 3941-3958 作者:  Ge, Haixia;  Ji, Beihong;  Fang, Jiahui;  Wang, Jiayang;  Li, Jing   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/11 function-based ligand design  receptor-ligandbinding profile  CB1/CB2  structure-activityrelationship   Breaking Tumor Immunosuppressive Network by Regulating Multiple Nodes with Triadic Drug Delivery Nanoparticles 期刊论文  OAI收割 ACS NANO, 2023, 卷号: 17, 期号: 18, 页码: 17826-17844 作者:  Yan, Wenlu;  Li, Yu;  Zou, Yiting;  Zhu, Runqi;  Wu, Ting   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 triple-negative breast cancer  antitumor immunity  tumor-associated macrophages  myeloid-derived suppressorcells  immune network  nanoparticle   Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 14 作者:  Li, Cuixia;  Wu, Yiran;  Wang, Wenli;  Xu, Lu;  Zhou, Yan   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17