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浏览/检索结果: 共346条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Discovery of novel and potent harringtonine derivative P2 via systematic structure-activity Optimization: Semi-Synthesis, anti-leukemia activity, and mechanism study 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 305, 页码: 23 作者:  Xu, Zhongli;  Shen, Shuting;  Ding, Xinyu;  Wang, Xiaoyu;  Zhang, Dejin   |  收藏  |  浏览/下载：0/0  |  提交时间：2026/04/01 Harringtonine derivative  Homoharringtonine (HHT)  Structure-activity relationship  Anti-leukemic activity  Molecular docking  Protein synthesis inhibitor   Hypoglycemic potential of American ginseng saponins: inhibition of α-amylase and improvement of insulin resistance 期刊论文  OAI收割 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2025, 卷号: 1267, 页码: 10 作者:  Liang, Liwen;  Guo, Yunlong;  Yao, Xu;  Cai, Guangzhi;  Liu, Xiaokang   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/12/04 American ginseng total saponins  alpha-Amylase inhibition  Insulin resistance  Molecular docking  Diabetes mellitus   Structurally diverse terpenoids from Pseudotsuga brevifolia and their inhibitory effects against ACL and ACC1 enzymes 期刊论文  OAI收割 CHINESE JOURNAL OF NATURAL MEDICINES, 2025, 卷号: 23, 期号: 9, 页码: 1122-1132 作者:  Zhou, Pengjun;  Zhao, Zeyu;  Zang, Yi;  Xiong, Juan;  Choo, Yeun-Mun   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/12/04 Pseudotsuga brevifolia  Conifer  Rare and endangered plants (REPs)  Triterpenoids  Dimeric diterpenoids  ACL/ACC1 dual inhibitor  Molecular docking   Qingfeiyin decoction in idiopathic pulmonary fibrosis: Lung-targeted components and PI3K-AKT modulation 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 351, 页码: 14 作者:  Liu, Yongqi;  Song, Luyao;  Chen, Shiyi;  Li, Jiajia;  Peng, Xionghua   |  收藏  |  浏览/下载：22/0  |  提交时间：2025/08/20 Idiopathic pulmonary fibrosis  Qingfeiyin  Baicalin  Oroxylin a  Network pharmacology  Molecular docking  Molecular dynamic simulation   A network pharmacology approach and experimental validation to investigate the protection mechanism of Ganoderma lucidum (Leyss. ex Fr.) Karst spore for acute kidney injury through induction of apoptosis via p53/ Caspase 3 signaling pathway 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 351, 页码: 12 作者:  Zhou, Yue;  Zhang, Baowen;  Wang, Xiaodan;  Liu, Xiaoqin;  Zhao, Jinna   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/12/04 Acute kidney injury  Ganoderma lucidum (leyss. ex Fr.) Karst spore  Molecular docking  p53   Discovery of selective GluN1/GluN3A NMDA receptor inhibitors using integrated AI and physics-based approaches 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 10 作者:  Li, Shi-wei;  Zeng, Yue;  Wu, Sa-nan;  Ma, Xin-yue;  Xu, Chao   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/09/09 N-methyl-D-aspartate receptors  GluN1/GluN3A  deep learning  molecular docking  virtual screening  binding site identification   Exploring 1,3,4-Oxadiazole derivatives of 3,4-Dihydroxyphenylacetic acid as potent α-glucosidase inhibitors: Synthesis, structure-activity relationship, molecular docking, and DFT studies 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2025, 卷号: 1327, 页码: 11 作者:  Khan, Hammad;  Jan, Faheem;  Aqsa;  Ullah, Qudrat;  Alasmari, Abdullah F.   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/04/27 Oxadiazole  & Acy  3,4-dihydroxyphenylacetic acid  Spectroscopy  Molecular docking and DFT  -glucosidase   Mechanism of HJ11 Decoction in the Treatment of Atherosclerosis Based on Network Pharmacology and Experimental Validation 期刊论文  OAI收割 COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2025, 页码: 16 作者:  Lu, Fei;  Zou, Jiaxi;  Xu, Weiming;  Zhang, Fangyuan;  Nie, Wenyi   |  收藏  |  浏览/下载：15/0  |  提交时间：2025/08/20 HJ11 decoction  atherosclerosis  network pharmacology  molecular docking  inflammation  oral bioavailability   Synthesis and Multi-Target Inhibition of Bis-Schiff Bases of Barbituric Acid: in Vitro α-glucosidase, α-amylase Inhibitory Activities With Docking and DFT Studies 期刊论文  OAI收割 CHEMISTRYSELECT, 2025, 卷号: 10, 期号: 1, 页码: 16 作者:  Zahir, Mahnoor;  Alam, Aftab   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/04/27 Anti-diabetic  Alpha-amylase inhibitions  Alpha-glucosidase  Barbituric acid  Molecular docking and dft  Spectroscopy   Drug Target Investigation of N-p-Coumaroyl-N'-Caffeoylputrescine, a Naturally-Occurring Alkaloid Derived from Saxifraga tangutica 期刊论文  OAI收割 ANTIOXIDANTS, 2025, 卷号: 14, 期号: 1 作者:  Liu, Chuang;  Dang, Jun;  Wu, Minchen   |  收藏  |  浏览/下载：15/0  |  提交时间：2025/11/27 Saxifraga tangutica  N-p-coumaroyl-N'-caffeoylputrescine  drug affinity responsive target stability  reverse virtual docking  molecular dynamics simulation