机构

• 上海药物研究所 [4]

采集方式

• OAI收割 [4]

内容类型

• 期刊论文 [4]

发表日期

• 2025 [1]
• 2024 [1]
• 2023 [1]
• 2011 [1]

学科主题

筛选

浏览/检索结果: 共4条，第1-4条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 One stone two birds: Introducing piperazine into a series of nucleoside derivatives as potent and selective PRMT5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 18 作者:  Li, Huaxuan;  Yang, Hong;  Liu, Li;  Zheng, Jiahong;  Shi, Qiongyu   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/12/11 Protein arginine methyltransferase 5  Nucleoside derivatives  Piperazine  Metabolic stability  Symmetric dimethylarginines   Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 19 作者:  Chen, Yuting;  Wang, Zekun;  Zhang, Junjie;  Shi, Qiongyu;  Yang, Hong   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/05/07 PRMT5  Nucleoside derivatives  Methyltransferases  Structure -activity relationship   Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20 作者:  Chen, Yuting;  Shi, Qiongyu;  Yang, Hong;  Li, Jiayi;  Zhou, Kaixin   |  收藏  |  浏览/下载：33/0  |  提交时间：2023/04/10 Epigenetic  PRMT5 inhibitor  Nucleoside derivatives  Structure-activity Relationship Prodrug   designsynthesisandinvitroevaluationofmono222trifluoroethylestersmonolaminoacidesterprodrugsofacyclicnucleosidephosphonatesasantihbvagents 期刊论文  OAI收割 chinesechemicalletters, 2011, 卷号: 22, 期号: 12, 页码: 1387 作者:  Fu Xiaozhong;  Ou Yu;  Xin Jan;  Yang Yushe   |  收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01 CHRONIC HEPATITIS-B  INTRACELLULAR DELIVERY  DERIVATIVES  MCC-478  VIRUS  PMEA  Acyclic nucleoside phosphonates  L-Amino acid  Prodrug