机构

• 金属研究所 [2]
• 长春光学精密机械与物... [2]
• 上海药物研究所 [2]
• 海洋研究所 [2]
• 生态环境研究中心 [2]
• 合肥物质科学研究院 [2]
• 更多

采集方式

• OAI收割 [18]
• iSwitch采集 [1]

内容类型

• 期刊论文 [19]

发表日期

• 2019 [2]
• 2018 [1]
• 2017 [1]
• 2015 [1]
• 2013 [2]
• 2012 [1]
• 更多

学科主题

• Biochemist... [1]
• Cell Biolo... [1]
• Endocrinol... [1]
• Multidisci... [1]
• Oncology [1]
• Urology & ... [1]
• 更多

筛选

浏览/检索结果: 共19条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Aryl-phosphorus-containing flame retardants induce oxidative stress, the p53-dependent DNA damage response and mitochondrial impairment in A549 cells 期刊论文  OAI收割 ENVIRONMENTAL POLLUTION, 2019, 卷号: 250, 页码: 58-67 作者:  Yuan, Shengwu;  Han, Yingnan;  Ma, Mei;  Rao, Kaifeng;  Wang, Zijian   |  收藏  |  浏览/下载：23/0  |  提交时间：2020/10/21 Phosphorus-containing flame retardants  Reactive oxygen species  Mitochondrial damage  p53 transfection  Gene expression   Rotundic acid induces Cas3-MCF-7 cell apoptosis through the p53 pathway 期刊论文  OAI收割 Oncology Letters, 2019, 卷号: 17, 期号: 1, 页码: 630-637 作者:  M.L.Nan;  X.Wang;  H.J.Li;  D.H.Yu;  W.Y.Sun   |  收藏  |  浏览/下载：28/0  |  提交时间：2020/08/24 rotundic acid,apoptosis,p53,MCF-7 cells,breast-cancer cells,triterpene acids,caspase 3,expression,reconstitution,proteins,protects,trial,Oncology   Rotundic acid enhances the impact of radiological toxicity on MCF-7 cells through the ATM p53 pathway 期刊论文  OAI收割 International Journal of Oncology, 2018, 卷号: 53, 期号: 5, 页码: 2269-2277 作者:  Wang, Z. F.;  Sun, W. Y.;  Yu, D. H.;  Zhao, Y.;  Xu, H. M.   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/09/17 rotundic acid  radiation  apoptosis  ataxia-telangiectasia mutated  tumor protein p53  breast-cancer  ionizing-radiation  triterpene acids  trial  radiotherapy  expression  therapy  risk  atm  trastuzumab  Oncology   Benzo[a]pyrene induced p53-mediated cell cycle arrest, DNA repair, and apoptosis pathways in Chinese rare minnow (Gobiocypris rarus) 期刊论文  OAI收割 ENVIRONMENTAL TOXICOLOGY, 2017, 卷号: 32, 期号: 3, 页码: 979-988 作者:     |  收藏  |  浏览/下载：19/0  |  提交时间：2018/07/29 Benzo[a]Pyrene  Rare Minnow (Gobiocypris Rarus)  P53 Network Genes  Gene Expression  Histopathology   An Old Story Retold: Loss of G1 Control Defines A Distinct Genomic Subtype of Esophageal Squamous Cell Carcinoma 期刊论文  OAI收割 GENOMICS PROTEOMICS & BIOINFORMATICS, 2015, 卷号: 13 -   |  收藏  |  浏览/下载：15/0  |  提交时间：2020/10/26 RECURRENT SOMATIC MUTATIONS  ONCOGENE-INDUCED SENESCENCE  YES-ASSOCIATED PROTEIN  COPY-NUMBER ALTERATION  DNA-DAMAGE RESPONSE  GENE-EXPRESSION  WIDE ANALYSIS  CANCER  INSTABILITY  P53   Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割 PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299 作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua 收藏  |  浏览/下载：42/0  |  提交时间：2015/05/14 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.   Silibinin Triggers Apoptosis and Cell-Cycle Arrest of SGC7901 Cells 期刊论文  OAI收割 phytotherapy research, 2013, 卷号: 27, 期号: 3, 页码: 397-403 Zhang YX; Li QS; Ge YK; Chen YP; Chen J; Dong Y; Shi W 收藏  |  浏览/下载：17/0  |  提交时间：2014/04/16 DOWN-REGULATING SURVIVIN  SILYBUM-MARIANUM  CANCER CELLS  L GAERTN  CARCINOMA  SILYMARIN  P53  INHIBITION  EXPRESSION  PATHWAY   The Potential Roles of a Laminin Receptor in Adhesion and Apoptosis of Cells of the Marine Bivalve Meretrix meretrix 期刊论文  OAI收割 PLOS ONE, 2012, 卷号: 7, 期号: 10, 页码: e47104 作者:  You, Yanan;  Huan, Pin;  Wang, Xiaomei;  Liu, Baozhong 收藏  |  浏览/下载：25/0  |  提交时间：2013/09/24 TUMOR-CELLS  P53 EXPRESSION  PRECURSOR  PROTEIN  CARCINOMA  PEPTIDES  MATRIX  GROWTH  BCL-2  PCR   Small Interfering RNA for Effective Cancer Therapies 期刊论文  OAI收割 mini-reviews in medicinal chemistry, 2011, 卷号: 11, 期号: 2, 页码: 114-124 Wang X; Chen Y; Ren J; Qu X 收藏  |  浏览/下载：28/0  |  提交时间：2012/06/11 HUMAN BREAST-CANCER  TELOMERASE REVERSE-TRANSCRIPTASE  NASOPHARYNGEAL CARCINOMA-CELLS  HUMAN HEPATOCELLULAR-CARCINOMA  ABL GENE-EXPRESSION  IN-VIVO DELIVERY  POLO-LIKE KINASE  WILD-TYPE P53  DOWN-REGULATION  COLORECTAL-CARCINOMA   lithiumanantipsychoticdruggreatlyenhancesthegenerationofinducedpluripotentstemcells 期刊论文  OAI收割 cellresearch, 2011, 卷号: 21, 期号: 10, 页码: 1424 作者:  Wang Quan;  Xu Xinxiu;  Li Jun;  Liu Jing;  Gu Haifeng   |  收藏  |  浏览/下载：10/0  |  提交时间：2020/07/01 MOUSE FIBROBLASTS  SOMATIC-CELLS  EXPRESSION  COMPLEX  NANOG  OCT4  INHIBITOR  PATHWAY  LINES  P53  lithium  induced pluripotent stem cells  iPS  GSK3 beta  Nanog  LSD1  histone demethylase