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上海药物研究所 [8]
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Advances in biosynthesis of peptide drugs: Technology and industrialization
期刊论文
OAI收割
BIOTECHNOLOGY JOURNAL, 2023, 页码: 13
作者:
Wang, Jing
;
Chen, Long
;
Qin, Song
;
Xie, Mingyuan
;
Luo, Shi-Zhong
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/01/26
biosynthesis technology
industrialization
peptide drugs
peptide synthesis
Advances in biosynthesis of peptide drugs: Technology and industrialization
期刊论文
OAI收割
BIOTECHNOLOGY JOURNAL, 2023, 页码: 13
作者:
Wang, Jing
;
Chen, Long
;
Qin, Song
;
Xie, Mingyuan
;
Luo, Shi-Zhong
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/11/02
biosynthesis technology
industrialization
peptide drugs
peptide synthesis
Substitution of D-Arginine at Position 11 of & alpha;-RgIA Potently Inhibits & alpha;7 Nicotinic Acetylcholine Receptor
期刊论文
OAI收割
MARINE DRUGS, 2023, 卷号: 21, 期号: 6, 页码: 13
作者:
Wu, Yong
;
Zhang, Junjie
;
Ren, Jie
;
Zhu, Xiaopeng
;
Li, Rui
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2023/10/17
conotoxin
peptide synthesis
CD structure
electrophysiology
nicotinic acetylcholine receptors
Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 17
作者:
Lin, Lin
;
Lin, Guangyao
;
Zhou, Qingtong
;
Bathgate, Ross A. D.
;
Gong, Grace Qun
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/08/17
Synthesis
Structure-activity relationship
Relaxin family peptide receptor 4
Selective agonist
Molecular docking
Chemical protein synthesis-assisted high-throughput screening strategies for D-peptides in drug discovery
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31
作者:
Li, Ying
;
Cao, Xiuxiu
;
Tian, Changlin
;
Zheng, Ji-Shen
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/12/07
Chemical protein synthesis
Mirror-image proteins
Mirror-image phage display
Mirror-image one-bead one-compound (OBOC)
D-Peptide drug
Machine-Driven Chemoenzymatic Synthesis of Glycopeptide
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 6
作者:
Zhang, Jiabin
;
Liu, Ding
;
Saikam, Varma
;
Gadi, Madhusudhan R.
;
Gibbons, Christopher
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/12/24
automation
chemoenzymatic synthesis
machine-driven
peptide synthesizer
silica resin
Total synthesis of snake toxin α-bungarotoxin and its analogues by hydrazide-based native chemical ligation
期刊论文
OAI收割
Chinese Chemical Letters, 2018, 卷号: 29
-
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/10/26
Chemical synthesis
Native chemical ligation
Peptide hydrazide
Nicotinic acetylcholine receptors
Chemical synthesis and structural analysis of guanylate cyclase C agonist linaclotide
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2018, 卷号: 29
-
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收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/10/26
IRRITABLE-BOWEL-SYNDROME
RACEMIC PROTEIN CRYSTALLOGRAPHY
X-RAY STRUCTURES
GASTROINTESTINAL-TRACT
PREVALENCE
LIGATION
PATTERNS
IMPACT
Linaclotide
Guanylyl cyclase
Protein chemical synthesis
Fmoc solid phase peptide synthesis
Racemic crystallization
Diaminodiacid Bridges to Improve Folding and Tune the Bioactivity of Disulfide-Rich Peptides
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 卷号: 54, 期号: 48, 页码: 14276-14281
作者:
Guo, Ye
;
Sun, De-Meng
;
Wang, Feng-Liang
;
He, Yao
;
Liu, Lei
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2017/10/26
Disulfide-rich Peptide
Peptide Therapeutics
Peptide Synthesis
Protein Engineering
Protein Folding
Preparation of PEGA grafted poly(chloromethylstyrene-co-ethylene glycol dimethacrylate) monolith for high-efficiency solid phase peptide synthesis under continuous flow techniques
期刊论文
OAI收割
POLYMER, 2015, 卷号: 61, 期号: MAR, 页码: 115-122
作者:
Zhang, Rongyue
;
Li, Qiang
;
Huang, Yongdong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2015/05/12
Monolith
Solid phase peptide synthesis
Continuous flow technique