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Rational design and discovery of novel oxalate-like derivatives as aphid-repellent candidates based on odorant-binding protein 3
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1301, 页码: 11
作者:
Zhu, Ziwei
;
Li, Jianing
;
Liu, Chong
;
Li, Huilin
;
Lu, Xingxing
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/04/09
Odorant-binding protein
Oxalate-like derivatives
Rational design
Repellent activity
Behavioural control agents
Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15
作者:
Zhu, Cheng-Liang
;
Luo, Xiaomin
;
Tian, Tian
;
Rao, Zijian
;
Wang, Hanlin
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/08/16
AKT
Protein kinase B
PROTAC
Chemical degrader
Rational design
AlphaFold2 versus experimental structures: evaluation on G protein-coupled receptors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 7
作者:
He, Xin-heng
;
You, Chong-zhao
;
Jiang, Hua-liang
;
Jiang, Yi
;
Xu, H. Eric
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/08/16
G protein-coupled receptors
AlphaFold2
protein structure prediction
drug design
structural biology
Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists
期刊论文
OAI收割
PHARMACEUTICALS, 2022, 卷号: 15
作者:
Sun, Lei
;
Zheng, Zhi-Ming
;
Shao, Chang-Sheng
;
Zhang, Zhi-Yong
;
Li, Ming-Wei
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/12/22
glucagon-like peptide-1
GLP-1 receptor agonist
functional protein design
molecular dynamics simulation
long-acting antihyperglycemic
Rational Design of a Miniature Photocatalytic CO2-Reducing Enzyme
期刊论文
OAI收割
ACS CATALYSIS, 2021, 卷号: 11
作者:
Kang, Fuying
;
Yu, Lu
;
Xia, Yan
;
Yu, Minling
;
Xia, Lin
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/08/31
photosystem I
rational design
photosensitizer protein
iron-sulfur (Fe4S4) cluster
photocatalytic
CO2 reductase
Drug design targeting active posttranslational modification protein isoforms
期刊论文
OAI收割
MEDICINAL RESEARCH REVIEWS, 2021, 卷号: 41, 期号: 3, 页码: 1701-1750
作者:
Meng, Fanwang
;
Liang, Zhongjie
;
Zhao, Kehao
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/03/22
Allosteric Inhibitor
Covalent Inhibitor
Posttranslational Modifications
Precision Medicine
Protac Protein Degradation
Protein‐
Protein Interactions
Ptm Protein Isoforms
Rational Drug Design
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:
Liu,Jiangxin
;
Wu,Xing-De
;
Li,Wenyan
;
Yuan,Zaifeng
;
Yang,Kun
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/04/02
Pseudolaric acid A
Hsp90 inhibitor
Apoptosis
NMR
Structure-activity relationship
Photoaffinity-based probe
Protein-ligand interaction
MOLECULAR CHAPERONE
PROTEIN
TARGET
CANCER
KINASE
NMR
IDENTIFICATION
SELECTIVITY
BINDING
DESIGN
RaacLogo: a new sequence logo generator by using reduced amino acid clusters
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 3
作者:
Zheng, Lei
;
Liu, Dongyang
;
Yang, Wuritu
;
Yang, Lei
;
Zuo, Yongchun
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/02/24
sequence logo
reduced amino acid alphabets
protein design
web server
Peptides Co-Assembling into Hydrangea-Like Microstructures
期刊论文
OAI收割
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2020, 卷号: 20, 期号: 5, 页码: 3239-3245
作者:
Guo, Z
;
Shen, ZW
;
Wang, YJ
;
Tan, TY
;
Zhang, Y
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/09/06
PROTEIN SECONDARY STRUCTURE
NEURODEGENERATIVE DISEASES
AMYLOID HYPOTHESIS
ALZHEIMERS-DISEASE
DESIGN
FIBERS
SPECTROSCOPY
AGGREGATION
FIBRILS
INSULIN
A minimalist peptide ligand for IgG by minimizing the binding domain of protein A
期刊论文
OAI收割
BIOCHEMICAL ENGINEERING JOURNAL, 2019, 卷号: 151, 页码: 8
作者:
Wang, Weiying
;
Hao, Dongxia
;
Ge, Jia
;
Zhao, Lan
;
Huang, Yongdong
  |  
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2020/05/06
Affinity Purification Chromatography
Minimalist Peptide
Protein a
Igg
Rational Design