机构

• 上海药物研究所 [49]
• 大连化学物理研究所 [2]
• 昆明植物研究所 [1]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [53]

内容类型

• 期刊论文 [53]

发表日期

• 2024 [1]
• 2023 [2]
• 2022 [5]
• 2021 [10]
• 2020 [6]
• 2019 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共53条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with Gs proteins 期刊论文  OAI收割 CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 13 作者:  Cong, Zhaotong;  Zhao, Fenghui;  Li, Yang;  Luo, Gan;  Mai, Yiting   |  收藏  |  浏览/下载：21/0  |  提交时间：2024/03/13 Conserved class B GPCR activation by a biased intracellular agonist 期刊论文  OAI收割 NATURE, 2023, 页码: 25 作者:  Zhao, Li-Hua;  He, Qian;  Yuan, Qingning;  Gu, Yimin;  He, Xinheng   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23 作者:  Chen, Lili;  Yun, Ying;  Guo, Shimeng;  Wang, Xiaoyan;  Xiong, Muya   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Structure insights into selective coupling of G protein subtypes by a class B G protein-coupled receptor 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 13 作者:  Zhao, Li-Hua;  Lin, Jingyu;  Ji, Su-Yu;  Zhou, X. Edward;  Mao, Chunyou   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/04/10 Hepatic thyroid hormone signalling modulates glucose homeostasis through the regulation of GLP-1 production via bile acid-mediated FXR antagonism 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16 作者:  Yan, Ying;  Niu, Zhoumin;  Sun, Chao;  Li, Peng;  Shen, Siyi   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/12/13 Effects of site-directed mutagenesis of GLP-1 and glucagon receptors on signal transduction activated by dual and triple agonists 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13 作者:  Darbalaei, Sanaz;  Chang, Ru-lue;  Zhou, Qing-tong;  Chen, Yan;  Dai, An-tao   |  收藏  |  浏览/下载：20/0  |  提交时间：2022/09/30 glucagon-like peptide-1 receptor  glucagon receptor  dual and triple agonist  cAMP  pERK1/2  unimolecular polypharmacology   Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists 期刊论文  OAI收割 PHARMACEUTICALS, 2022, 卷号: 15 作者:  Sun, Lei;  Zheng, Zhi-Ming;  Shao, Chang-Sheng;  Zhang, Zhi-Yong;  Li, Ming-Wei   |  收藏  |  浏览/下载：16/0  |  提交时间：2022/12/22 glucagon-like peptide-1  GLP-1 receptor agonist  functional protein design  molecular dynamics simulation  long-acting antihyperglycemic   Structural basis of peptidomimetic agonism revealed by small-molecule GLP-1R agonists Boc5 and WB4-24 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 20, 页码: 10 作者:  Cong, Zhaotong;  Zhou, Qingtong;  Li, Yang;  Chen, Li-Nan;  Zhang, Zi-Chen   |  收藏  |  浏览/下载：29/0  |  提交时间：2022/09/30 glucagon-like peptide-1 receptor  type 2 diabetes mellitus  cryoelectron microscopy  peptidomimetic agonism   GLP-1 mimetics as a potential therapy for nonalcoholic steatohepatitis 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Chen, Yan;  Xu, Ying-na;  Ye, Chen-yu;  Feng, Wen-bo;  Zhou, Qing-tong   |  收藏  |  浏览/下载：17/0  |  提交时间：2022/06/15 NAFLD  NASH  GLP-1R  GLP-1 mimetics  dual agonists  triple agonists  GPCR   Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16 作者:  Yuliantie, Elita;  van der Velden, Wijnand J. C.;  Labroska, Viktorija;  Dai, Antao;  Zhao, Fenghui   |  收藏  |  浏览/下载：94/0  |  提交时间：2021/11/04 Glucose-dependent insulinotropic polypeptide receptor  G protein-coupled receptor  GPCR structure-function relationship  ERK  cAMP  Arrestin