机构

• 上海药物研究所 [4]
• 生态环境研究中心 [2]
• 大连化学物理研究所 [1]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2025 [1]
• 2019 [1]
• 2018 [1]
• 2016 [1]
• 2014 [1]
• 2012 [2]
• 更多

学科主题

• 物理化学 [1]

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21 作者:  Sui, Qibang;  Zhou, Yuanyang;  Li, Manjia;  Wang, Dan;  Cui, Rongrong   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/12/25 Synthetic lethal  MSI tumors  WRN inhibitors  Triazolo-pyrimidine derivatives   Design, synthesis, and biological evaluation of thieno[3,2-d]pyrimidine derivatives as potential simplified phosphatidylinositol 3-kinase alpha inhibitors 期刊论文  OAI收割 CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 94, 期号: 6, 页码: 2013-2022 作者:  Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Wang, Yi;  Song, Kun   |  收藏  |  浏览/下载：46/0  |  提交时间：2020/07/01 PI3K alpha inhibitors  proliferation inhibition  thieno[3  2-d]pyrimidine derivatives   Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 298-306 作者:  Yan, Qi;  Chen, Yuzhe;  Tang, Baiyou;  Xiao, Qiang;  Qu, Rong   |  收藏  |  浏览/下载：84/0  |  提交时间：2019/01/08 EGFR inhibitors  Pyrimidine derivatives  Mutant selective inhibitors  AZD9291  T790M   Discovery of 5-(methylthio)pyrimidine derivatives as L858R/T790M mutant selective epidermal growth factor receptor (EGFR) inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 12, 页码: 2673-2680 作者:  Xiao, Qiang;  Qu, Rong;  Gao, Dingding;  Yan, Qi;  Tong, Linjiang   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 5-(Methylthio)pyrimidine derivatives  Mutant selective inhibitors  Epidermal growth factor inhibitor  NSCLC  Structure-based drug design   Insight into the binding mode and the structural features of the pyrimidine derivatives as human A(2A) adenosine receptor antagonists 期刊论文  OAI收割 biosystems, 2014, 卷号: 115, 期号: 1, 页码: 13-22 作者:  Zhang, Lihui;  Liu, Tianjun;  Wang, Xia;  Wang, Jinan;  Li, Guohui 收藏  |  浏览/下载：30/0  |  提交时间：2015/11/16 Pyrimidine derivatives  Human A(2A) adenosine receptor  Molecular docking  Molecular dynamics  Thermodynamic analysis  3D-QSAR   Synthesis and Antifungal Activities of New Type beta-Methoxyacrylate-Based Strobilurin Analogues 期刊论文  OAI收割 CHINESE JOURNAL OF CHEMISTRY, 2012, 卷号: 30, 期号: 7, 页码: 1517－1524 Zhang Xiang; Liu Huijun; Gao Yongxin; Wang Huili; Guo Baoyuan; Li Jianzhong 收藏  |  浏览/下载：18/0  |  提交时间：2014/11/05 synthesis  strobilurin derivatives  antifungal activities  substituted pyrimidine  SAR   Design, Synthesis and Antifungal Activities of Novel Strobilurin Derivatives Containing Pyrimidine Moieties 期刊论文  OAI收割 Chemistry, 2012, 卷号: 33, 期号: 8, 页码: 2627-2634 Zhang, Xiang; Gao, Yong-Xin; Liu, Hui-Jun; Guo, Bao-Yuan; Wang, Hui-Li 收藏  |  浏览/下载：18/0  |  提交时间：2014/11/28 Synthesis  Strobilurin derivatives  Antifungal activities  Pyrimidine