中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
福建物质结构研究所 [14]
上海药物研究所 [14]
长春应用化学研究所 [14]
宁波材料技术与工程研... [7]
上海应用物理研究所 [7]
合肥物质科学研究院 [4]
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OAI收割 [78]
内容类型
期刊论文 [75]
会议论文 [3]
发表日期
2025 [1]
2024 [3]
2023 [2]
2022 [3]
2021 [6]
2020 [6]
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Chemistry [2]
Materials ... [2]
Biochemist... [1]
Energy & F... [1]
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Targeting Two Odorant-Binding Proteins in Acyrthosiphon pisum: Discovery of Novel Jasmone Derivatives as Aphid Repellents
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2025, 卷号: 73, 期号: 19, 页码: 11998-12013
作者:
Zhu, Ziwei
;
Li, Huilin
;
Zhu, Wenya
;
Du, Shaoqing
;
Yang, Zhaokai
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
odorant-binding proteins
jasmone derivatives
rational design
aphid repellents
insect behaviorregulators
Enhanced molecular stability of ApxII antigen during secretion in Corynebacterium glutamicum by rational design
期刊论文
OAI收割
JOURNAL OF BIOTECHNOLOGY, 2024, 卷号: 394
作者:
Liu, Xiuxia
;
Yang, Shujie
;
Sun, Manman
;
Gao, Alex Xiong
;
Fan, Ziming
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/11/20
Truncated ApxII
Molecular stability towards proteolytic
degradation
Corynebacterium glutamicum
Rational design
Rational design and discovery of novel oxalate-like derivatives as aphid-repellent candidates based on odorant-binding protein 3
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1301, 页码: 11
作者:
Zhu, Ziwei
;
Li, Jianing
;
Liu, Chong
;
Li, Huilin
;
Lu, Xingxing
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/04/09
Odorant-binding protein
Oxalate-like derivatives
Rational design
Repellent activity
Behavioural control agents
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:
Qin, Ying
;
Li, Dekang
;
Qi, Chunting
;
Xiang, Huaijiang
;
Meng, Huyan
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/03/06
RIPK1
Necroptosis
Type-II kinase inhibitors
Rational design
Lead optimization
Structure-activity relationship
Anti-inflammation
Preclinical drug discovery
Development of PI3Kγ selective inhibitors: the strategies and application
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 10
作者:
Gu, Dong-Yan
;
Zhang, Meng-Meng
;
Li, Jia
;
Zhou, Yu-Bo
;
Sheng, Rong
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/12/08
PI3K
PI3K gamma inhibitors
isoform selectivity
drug development
rational drug design
Improved 2α-Hydroxylation Efficiency of Steroids by CYP154C2 Using Structure-Guided Rational Design
期刊论文
OAI收割
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2023, 卷号: 89, 期号: 3
作者:
Gao, Qilin
;
Ma, Bingbing
;
Wang, Qianwen
;
Zhang, Hao
;
Fushinobu, Shinya
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/03/27
P450
testosterone
androstenedione
crystal structure
rational design
The rational design of iron-sulfur cluster binding site for prolonged stability in magnetoreceptor MagR
期刊论文
OAI收割
FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 卷号: 9
作者:
Tong, Tianyang
;
Zhou, Yajie
;
Fei, Fan
;
Zhou, Xiujuan
;
Guo, Zhen
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2022/12/23
iron-sulfur cluster
magnetoreceptor
MagR
rational design
thermostability
Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15
作者:
Zhu, Cheng-Liang
;
Luo, Xiaomin
;
Tian, Tian
;
Rao, Zijian
;
Wang, Hanlin
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/08/16
AKT
Protein kinase B
PROTAC
Chemical degrader
Rational design
A Rationally Designed Building Block of the Putative Magnetoreceptor MagR
期刊论文
OAI收割
BIOELECTROMAGNETICS, 2022, 卷号: 43
作者:
Yang, Peilin
;
Cai, Tiantian
;
Zhang, Lei
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/12/23
magnetoreception
MagR
rational design
single-chain-tetramer
building block
Rational Design of a Miniature Photocatalytic CO2-Reducing Enzyme
期刊论文
OAI收割
ACS CATALYSIS, 2021, 卷号: 11
作者:
Kang, Fuying
;
Yu, Lu
;
Xia, Yan
;
Yu, Minling
;
Xia, Lin
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/08/31
photosystem I
rational design
photosensitizer protein
iron-sulfur (Fe4S4) cluster
photocatalytic
CO2 reductase