机构

• 上海药物研究所 [17]
• 过程工程研究所 [2]
• 福建物质结构研究所 [1]
• 化学研究所 [1]
• 上海神经科学研究所 [1]
• 合肥物质科学研究院 [1]
• 更多

采集方式

• OAI收割 [24]

内容类型

• 期刊论文 [23]
• 会议论文 [1]

发表日期

• 2025 [1]
• 2023 [2]
• 2022 [1]
• 2020 [1]
• 2018 [1]
• 2015 [2]
• 更多

学科主题

• Chemistry [6]
• Pharmacolo... [6]
• Biochemist... [4]
• Biophysics [1]
• Oncology [1]

筛选

浏览/检索结果: 共24条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择作者升序作者降序发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序 Molecular basis for ligand recognition and receptor activation of the prostaglandin D2 receptor DP1 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2025, 卷号: 122, 期号: 22, 页码: 11 作者:  Xu, Jiuyin;  Wu, Yanli;  Xu, Youwei;  Li, Yang;  He, Xinheng   |  收藏  |  浏览/下载：19/0  |  提交时间：2025/08/20 prostaglandin D2 receptor 1  receptor activation  drug design   Discovery of Potent and Selective CB2 Agonists Utilizing a Function-Based Computational Screening Protocol 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2023, 卷号: 14, 期号: 21, 页码: 3941-3958 作者:  Ge, Haixia   |  收藏  |  浏览/下载：54/0  |  提交时间：2023/12/11 function-based ligand design  receptor-ligandbinding profile  CB1/CB2  structure-activityrelationship   Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16 作者:  Chen, Yun;  Ning, Yi;  Chen, Zhiwei;  Xue, Yaping;  Wu, Qingyun   |  收藏  |  浏览/下载：58/0  |  提交时间：2023/10/17 Apoptosis  Diffuse large B-Cell lymphoma  Interleukin-1 receptor associated kinase 4  Structure-based drug design  2  3-Dihydrobenzofuran   Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists 期刊论文  OAI收割 PHARMACEUTICALS, 2022, 卷号: 15 作者:  Sun, Lei;  Zheng, Zhi-Ming;  Shao, Chang-Sheng;  Zhang, Zhi-Yong;  Li, Ming-Wei   |  收藏  |  浏览/下载：40/0  |  提交时间：2022/12/22 glucagon-like peptide-1  GLP-1 receptor agonist  functional protein design  molecular dynamics simulation  long-acting antihyperglycemic   Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190, 页码: 14 作者:  Chen, Yun;  Bai, Gang;  Ning, Yi;  Cai, Shi;  Zhang, Tao   |  收藏  |  浏览/下载：74/0  |  提交时间：2020/07/01 lnterleukin-1 receptor associated kinase 4  Imidazol1,2-6]pyridazine  Diffuse large B-cell lymphoma  Drug design  Antitumor agents   Recent Trends and Applications of Molecular Modeling in GPCR-Ligand Recognition and Structure-Based Drug Design 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 7 作者:  Yuan, Xiaojing;  Xu, Yechun   |  收藏  |  浏览/下载：48/0  |  提交时间：2019/01/08 GPCR  receptor-ligand recognition  drug design  molecular modeling  molecular dynamics  docking  binding affinity  binding pathway   Bacterial chemoreceptors and chemoeffectors 期刊论文  OAI收割 CELLULAR AND MOLECULAR LIFE SCIENCES, 2015, 卷号: 72, 期号: 4, 页码: 691-708 作者:  Bi, Shuangyu;  Lai, Luhua   |  收藏  |  浏览/下载：52/0  |  提交时间：2019/04/09 Chemotactic Response  Receptor  Ligand  Molecular Mechanism  Receptor Design   Androgen receptor: structure, role in prostate cancer and drug discovery 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 1, 页码: 3-23 作者:  Tan, M. H. Eileen;  Li, Jun;  Xu, H. Eric;  Melcher, Karsten;  Yong, Eu-leong   |  收藏  |  浏览/下载：53/0  |  提交时间：2019/01/08 androgen  androgen receptor  prostate cancer  nuclear receptor  drug discovery  rational drug design  structural biology  castration resistance  antiandrogen   Design,Synthesis and Evaluation of Indolebutylamines as a Novel Class of Selective Dopamine D3 Receptor Ligands 会议论文  OAI收割 作者:  Xu LL(徐丽丽);  Du P(杜鹏);  Yu KQ(于坤千);  Zhao WL(赵伟利);  Zhen XC(镇学初)   |  收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08 Design,Synthesis and Evaluation of Indolebutylamines as a Novel Class of Selective Dopamine D3 Receptor Ligands   Gold nanoparticle-based colorimetric assay for selective detection of aluminium cation on living cellular surfaces 期刊论文  OAI收割 chemical communications, 2010, 卷号: 46, 期号: 6, 页码: 988-990 Li XK; Wang JN; Sun LL; Wang ZX 收藏  |  浏览/下载：19/0  |  提交时间：2012/06/07 AQUEOUS-MEDIA  IONS  DISEASE  SENSOR  BRAIN  MERCURY(II)  TRANSFERRIN  RECEPTOR  DESIGN  PB2+